Rheumatic disease is a major cause of morbidity and disability in the Western world. There have been major developments in our understanding of the causes of rheumatic disease and in their treatment during the last half-century, and there are relatively few papers which can be regarded as truly 'landmark' in their construction and subsequent findings. Part of the Landmark Papers in series, this book provides a detailed review of the seminal papers that have paved the way for breakthroughs in the clinical management of the entire spectrum of rheumatic diseases.

There have been major developments in our understanding of the causes of rheumatic disease and in their treatment during the last half-century. This book provides a detailed review of the seminal papers that have paved the way for breakthroughs in the clinical management of the entire spectrum of rheumatic disease.

ACPs journal, Annals of Internal Medicine, is one of the most prestigious journals in medicine. This new book looks at the landmark papers published in Annals, as selected by leading experts from each subspecialty of internal medicine, and how they impacted (and continue to influence) medical science.

This is a handbook of clinical rheumatology that provides practical guidelines to management and diagnosis. It is essential for all specialist registrars and SHO's but will also be of great relevance to general practitioners.

Pain Medicine, a relatively new specialty, has proven increasingly relevant to medical practitioners in every field. The specialism of pain has emerged over the past 50 years, largely due to the persistence of experts and new medical evidence that points to its necessity. Today, it is a distinct and integral part of global medical practice. Landmark Papers in Pain offers a comprehensive inventory of over 80 key studies in pain medicine from the last 100 years. Each paper is accompanied by a concise commentary on the significance of the original findings written by an expert in pain. The reviews discuss how the paper influenced the development of the speciality, and how the findings have advanced our global comprehension of pain. Together, the selected papers and reviews chart the growth of an embryonic field into the modern speciality of pain medicine. Complied by leading specialists in the field, the papers included in this book are significant for any student, researcher, clinical practitioner, or medical historian interested in pain medicine. Organised into eight distinct topics and cross-referenced by topics and author of original paper, the book is comprehensive in its coverage and easy to use. A review of the contemporary and historical research that shaped the speciality of pain, Landmark Papers in Pain is essential reading for all medical practitioners with an interest in pain medicine.

The guideline covers the management of people with rheumatoid arthritis all the way through the disease process - from early identification to sever disease.

Landmark Papers in Cardiovascular Medicine provides a thorough and wide-ranging analysis of core examples of novel research, clinical trials and seminal papers that have paved the way for breakthroughs in the management of the entire spectrum of cardiovascular disease.