Alphaherpesviruses

Alphaherpesviruses
Title Alphaherpesviruses PDF eBook
Author Sandra Knowles Weller
Publisher Caister Academic Press Limited
Pages 0
Release 2011
Genre Science
ISBN 9781904455769

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Alphaherpesviruses are a fascinating group of DNA viruses that includes important human pathogens such as herpes simplex virus type 1 (HSV-1), HSV-2, and varicella-zoster virus (VZV): the causative agents of cold sores, genital ulcerous disease, and chickenpox/shingles, respectively. A key attribute of these viruses is their ability to establish lifelong latent infection in the peripheral nervous system of the host. Such persistence requires subversion of the host's immune system and intrinsic antiviral defense mechanisms. Understanding the mechanisms of the immune evasion and what triggers viral reactivation is a major challenge for today's researchers. This has prompted enormous research efforts into understanding the molecular and cellular biology of these viruses. This up-to-date and comprehensive volume aims to distill the most important research in this area providing a timely overview of the field. Topics covered include: transcriptional regulation, DNA replication, translational control, virus entry and capsid assembly, the role of microRNAs in infection and oncolytic vectors for cancer therapy. In addition there is coverage of virus-host interactions, including apoptosis, subversion of host protein quality control and DNA damage response pathways, autophagy, establishment and reactivation from latency, interferon responses, immunity and vaccine development. Essential reading for everyone working with alphaherpesviruses and of interest to all virologists working on latent infections.

Tile & Till

Tile & Till
Title Tile & Till PDF eBook
Author
Publisher
Pages 536
Release 1915
Genre Pharmacy
ISBN

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Type & Typo

Type & Typo
Title Type & Typo PDF eBook
Author
Publisher Omair Nazir
Pages 18
Release
Genre
ISBN

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Antifascisms

Antifascisms
Title Antifascisms PDF eBook
Author David Ward
Publisher Fairleigh Dickinson Univ Press
Pages 260
Release 1996
Genre History
ISBN 9780838636763

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This book is an in-depth analysis of three of the most crucial years in twentieth-century Italian history, the years 1943-46. After more than two decades of a Fascist regime and a disastrous war experience during which Italy changed sides, these years saw the laying of the political and cultural foundations for what has since become known as Italy's First Republic. Drawing on texts from the literature, film, journalism, and political debate of the period, Antifascisms offers a thorough survey of the personalities and positions that informed the decisions taken in this crucial phase of modern Italian history.

Fletcherism, what it is

Fletcherism, what it is
Title Fletcherism, what it is PDF eBook
Author Horace Fletcher
Publisher
Pages 260
Release 1913
Genre Mastication
ISBN

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Bacchantes

Bacchantes
Title Bacchantes PDF eBook
Author Euripides
Publisher
Pages 144
Release 1899
Genre
ISBN

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Yvain

Yvain
Title Yvain PDF eBook
Author Chretien de Troyes
Publisher Yale University Press
Pages 242
Release 1987-09-10
Genre Poetry
ISBN 0300187580

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The twelfth-century French poet Chrétien de Troyes is a major figure in European literature. His courtly romances fathered the Arthurian tradition and influenced countless other poets in England as well as on the continent. Yet because of the difficulty of capturing his swift-moving style in translation, English-speaking audiences are largely unfamiliar with the pleasures of reading his poems. Now, for the first time, an experienced translator of medieval verse who is himself a poet provides a translation of Chrétien’s major poem, Yvain, in verse that fully and satisfyingly captures the movement, the sense, and the spirit of the Old French original. Yvain is a courtly romance with a moral tenor; it is ironic and sometimes bawdy; the poetry is crisp and vivid. In addition, the psychological and the socio-historical perceptions of the poem are of profound literary and historical importance, for it evokes the emotions and the values of a flourishing, vibrant medieval past.