For many years "safety technology" has constituted the essential instrument for the prevention of accidents as a direct result of handling new technology. Its awareness of the interactions prevalent in natural science causes safety technology to act on the basis of actual accidents, and it Ulilizes to their fullest extent any means provided by the engineering sciences. Man proceeds in a general direction towards preselVation and improvement, thus working towards the optimization of the technical design. However. a new set of basic problems presented itself the moment new large-scale technologies were introduced into the areas of processing, energy, and traffic, thereby creating a considerable amount of ad ditional danger potential. This also signified the end of an era when safety technology could be practiced chiefly on the basis of accident statistics. For ethical reasons it became necessary that a credible prognosis as to the type and effect of accidents took the place, or at least supplemented, the hitherto practiced purely reactive methods. The realization that the available means of safety technology were no longer sufficient in a highly technologized environment spurred the demand for entirely new concepts which would eventually lead to a higher degree of safety. A decisive step had to be taken away from a purely technical approach and fOwards and all-encompassing look at accident systems, because man had become aware of the fact that accidents will always be a part of the interaction between man, technology, and environment.

Safety Science Research: Evolution, Challenges and New Directions provides a unique perspective into the latest developments of safety science by putting together, for the first time, a new generation of authors with some of the pioneers of the field. Forty years ago, research traditions were developed, including, among others, high-reliability organisations, cognitive system engineering or safety regulations. In a fast-changing world, the new generation introduces, in this book, new disciplinary insights, addresses contemporary empirical issues, develops new concepts and models while remaining critical of safety research practical ambitions. Their ideas are then reflected and discussed by some of the pioneers of safety science. Features Allows the reader to discover how contemporary safety issues are currently framed by a new generation of researchers, brought together for the first time Includes an introduction and guide to the development of safety science over the last four decades Features an extraordinary collection of expert contributors, including pioneers of safety research, reflecting the evolution of the discipline and offering insightful commentary on the current and future state of the field Serves as an invaluable reference and guide for safety professionals and students from any established disciplines such as sociology, engineering, psychology, political science or management as well as dedicated safety programmes Some figures in the eBook are in colour

The book is designed as an accessible and readable introduction to a rapidly expanding area that is in demand worldwide. A variety of professionals from different backgrounds are being tasked with managing health and safety risks in a wide variety of settings. Many lack current and up-to-date knowledge of the key developments that have taken place in Safety Science in recent decades, as well as a sense of how these developments fit in with previous approaches. This book takes readers on a ‘journey’ across three broad developments in safety science. It covers topics that focus on the individual including human error, risk and the role of cognition in human performance. It then shifts to research in safety science that uses organizations as the basic unit of analysis, questions about organizational decision making and the characteristics that dispose towards or against organizational failure and it introduces perspectives based on systems science that address issues that arise out of complexity and interdependence. Those who will purchase this book are students taking courses in human factors, ergonomics, applied psychology, occupational health and safety management. Professionals working in safety management in any field from agriculture, construction, shipping, aviation, power generation, oil exploration, manufacturing to healthcare will find this book useful, as well as general readers interested in why systems fail.

This book takes a systems-thinking approach to allow readers to understand how Workplace safety and health (WSH) is an integral part of any organisation. The different chapters are strung together by an overarching model of incident causation, and underpinning models are presented to allow a strong conceptual foundation. Practical WSH knowledge also discussed in relevant chapters to ensure that beginners have an introduction to the fundamentals of WSH hazards and controls.The second edition presents additional systems thinking concepts and archetypes not covered previously, the safe design process in Australia, thoughts on learning disabilities and safety culture, and additional case studies. Besides the strong emphasis on conceptual framework, readers will also be exposed to the details of a WSH management system and practical WSH processes, hazards and controls. A series of online quizzes are available to readers to help them to reinforce the concepts of each chapter.Undergraduates and post-graduates will benefit from the systematic introduction to the foundations of WSH management. Practitioners will strengthen their conceptual understanding and widen their perspective by re-visiting the foundations of WSH management through a systems-thinking lens.

Includes Case Studies from a Range of Event Sites Introduction to Crowd Science examines the growing rate of crowd-related accidents and incidents around the world. Using tools, methods, and worked examples gleaned from over 20 years of experience, this text provides an understanding of crowd safety. It establishes how crowd accidents and incidents (specifically mass fatalities in crowded spaces) can occur. The author explores the underlying causes and implements techniques for crowd risk analysis and crowd safety engineering that can help minimize and even eliminate occurrences altogether. Understand Overall Crowd Dynamics and Levels of Complex Structure The book outlines a simple modeling approach to crowd risk analysis and crowds safety in places of public assembly. With consideration for major events, and large-scale urban environments, the material focuses on the practical elements of developing the crowd risk analysis and crowd safety aspects of an event plan. It outlines a range of modeling techniques, including line diagrams that represent crowd flow, calculations of the speed at which a space can fill, and the time it takes for that space to reach critical and crush density. It also determines what to consider during the event planning and approval (licensing/permitting) phases of the event process. Introduction to Crowd Science addresses key questions and presents a systematic approach to managing crowd risks in complex sites. It provides an understanding of the complexity of a site, that helps youplan for crowds in public places.

In recent years, the costs of new drug development have skyrocketed. The average cost of developing a new approved drug is now estimated to be $1.3 billion (DiMasi and Grabowski, 2007). At the same time, each year fewer new molecular entities (NMEs) are approved. DiMasi and Grabowski report that only 21.5 percent of the candidate drugs that enter phase I clinical testing actually make it to market. In 2007, just 17 novel drugs and 2 novel biologics were approved. In addition to the slowing rate of drug development and approval, recent years have seen a number of drugs withdrawn from the market for safety reasons. According to the Government Accountability Office (GAO), 10 drugs were withdrawn because of safety concerns between 2000 and March 2006 (GAO, 2006). Finding ways to select successful drug candidates earlier in development could save millions or even billions of dollars, reduce the costs of drugs on the market, and increase the number of new drugs with improved safety profiles that are available to patients. Emerging scientific knowledge and technologies hold the potential to enhance correct decision making for the advancement of candidate drugs. Identification of safety problems is a key reason that new drug development is stalled. Traditional methods for assessing a drug's safety prior to approval are limited in their ability to detect rare safety problems. Prior to receiving U.S. Food and Drug Administration (FDA) approval, a drug will have been tested in hundreds to thousands of patients. Generally, drugs cannot confidently be linked to safety problems until they have been tested in tens of thousands to hundreds of thousands of people. With current methods, it is unlikely that rare safety problems will be identified prior to approval. Emerging Safety Science: Workshop Summary summarizes the events and presentations of the workshop.

Food safety is a multi-faceted subject, using microbiology, chemistry, standards and regulations, and risk management to address issues involving bacterial pathogens, chemical contaminants, natural toxicants, additive safety, allergens, and more. This revised edition has been updated with the latest information on food safety. It addresses all the topics pertinent to a full understanding of keeping the food we eat safe. Each chapter of Food Safety: The Science of Keeping Food Safe, Second Edition proceeds from introductory concepts and builds towards a sophisticated treatment of the topic, allowing the reader to take what knowledge is required for understanding food safety at a wide range of levels. Illustrated with photographs and examples throughout, this new edition also boasts 4 new chapters covering radioactivity in food; food terrorism; food authenticity; and food supplements. • This second edition has been revised and updated throughout to include the latest topics in this fast-moving field • Includes 4 brand new chapters on radioactivity in food, food terrorism, food authenticity, and food supplements • The most readable and user-friendly food safety book for students, scientists, regulators, and general readers Food Safety is the ideal starting point for students and non-specialists seeking to learn about food safety issues, and an enjoyable and stylish read for those who already have an academic or professional background in the area.