Intracranial germ cell tumors are a group of uncommon neoplasms of the central nervous system. The clinical features and natural history of these lesions are quite unique and variable. While intracranial germ cell tumors have been a fascination to neurooncologists for decades, the relatively small number of patients seen in any single institution has hampered the important clinical investigation that is so needed. This text is complete with detailed information concerning the epidemiology, pathology, oncological biology, clinical findings, radiology, and treatment options including surgical strategy, radiotherapy, and chemotherapy for this heterogeneous group of neoplasms. The ongoing clinical trials concerning the optimization of therapy are efficiently summarized. An important final segment addresses the late sequelae of therapy which is of great significance since the majority suffering from these tumors are young patients. This first and only book on intracranial germ cell tumors includes excellent and comprehensive data sheets, illustrations, and radiograms. It provides a detailed and outstanding reference source for physicians taking care of patients with intracranial germ cell tumors, and will be a very welcome edition to their reference libraries.

This book provides evidence-based management in neuro-oncology covering all aspects such as pathology, radiology, surgery, radiation, and chemotherapy.The field of neuro-oncology is rapidly evolving and new evidence is coming out every day towards the optimal management of brain tumors. This necessitates a requirement of a complete guide that shall provide an evidence-based and personalized approach towards dealing with patients. This book also covers recent advances in personalized treatment formed through the relevant basis of anatomy, imaging, radiology, surgical, radiation and systemic treatment of brain and spinal tumors. In addition it also covers the , practical aspects of the planning of the Gamma knife and other radio surgical aspects. The book shall provide valuable assistance to practicing neuro-oncologists to practice better evidence-based personalized medicine.

This book is a practical, up-to-date guide to the treatment of patients with brain and spinal tumors. Leading experts in the field explain treatment techniques in detail, highlighting key considerations in the use of external beam radiation therapy, intensity-modulated radiation therapy, particle therapy, radiosurgery, and stereotactic body radiation therapy. Specific recommendations are described for different tumor types, and helpful information provided on other important issues, such as the interaction of radiotherapy and systemic therapy and the avoidance of treatment complications. With the development of modern technology, highly conformal radiotherapy techniques have become more complicated, yet also more widely employed. This book will equip readers with the knowledge required to set up practices to deliver quality brain and spinal radiation therapy appropriate to each patient. It will be of benefit to radiation oncologists, clinical oncologists, medical physicists, medical dosimetrists, radiation therapists, and senior nurses as well as medical oncologists and surgical oncologists with an interest in radiotherapy.

Germ cell tumors are relatively rare compared with other malignancies, and compilations of knowledge that encompass the entire spectrum of the disease are lacking. This textbook, written by the foremost authorities in the field, rectifies the situation by discussing in depth a broad range of topics, including biology, epidemiology, pathology, treatment, and late effects. Bearing in mind that germ cell tumors are most prevalent in the adolescent and young adult age group, causes of disease and treatment approaches in pediatric and adult patients are compared and contrasted. By spanning the entire life course, from prenatal origins of disease through to treatment in adults and late effects of treatment, the editors have produced a book that will be of interest to both pediatric and adult oncologists.

This book presents, in a stepwise and interactive fashion, approximately 75 cases that reflect the wide spectrum of pathology encountered in this region. Each case description commences with a concise clinical scenario. High-quality radiologic, laboratory, and histopathologic images depicting the differentiating features of the lesion subtype in question are then presented, and key operative and clinical management pearls are briefly reviewed. The interdisciplinary nature of this easy-to-use color atlas and textbook reflects the fact that the management of patients with sellar and parasellar lesions is itself often interdisciplinary. The format is unique in that no similar interdisciplinary book is available on lesions of this region of the brain. Atlas of Sellar and Parasellar Lesions: Clinical, Imaging, and Pathologic Correlations is of great value for practitioners and trainees in a range of medical specialties, including radiology, neurology, endocriniology, pathology, oncology, radiation oncology, and neurosurgery.

This highly illustrated book explores the pathological and radiological diagnosis of various brain tumors. Featuring nearly 500 high-quality colored images, it covers MR images, intra-operative squash cytology, histopathology and immunohistochemistry microphotographs of various brain and spine tumors, including differential diagnosis, as well as the molecular diagnosis and prognosis of each tumor. The book also presents case studies of typical and rare presentations, and introduces readers to a new procedure for intra-operative cytology: the modified fields stain, which stains the slide within 2 minutes, allowing quick, accurate reporting. This book uses concise text and a consistent point-wise format that makes reading and reviewing easy. The radiological and pathological correlates of brain and spine tumors serve as a ready-reference resource for residents, surgical and neuropathologists, neuroradiologists, neurosurgeons, neuro-oncologists and research scientists.

The pineal region is an anatomic location where various intracranial tumors, in particular germ cell tumors and pineal parenchymal tumors, occur. Interestingly, pineal germ cell tumors are detected more frequently in Asian countries, including Japan, while pineal parenchymal tumors are less frequent in Asia than in the United States and Europe. This publication takes advantage of the knowledge and experience of Japanese experts in pineal tumors, with emphasis on epidemiology and pathological diagnosis. A variety of treatment modalities including radiotherapy, radiosurgery, surgical therapy and chemotherapy are also discussed. This valuable book will enhance the knowledge on pineal tumor treatment of not only neurosurgeons and radiation oncologists but also neurologists, neuro-oncologists, pediatricians and neuropathologists interested in pineal region tumors.