This book presents the work of researchers in the Esprit Fully Integrated Data Environments (FIDE) projects which had the goal of substantially improving the quality of complex application systems while massively reducing the cost of building and maintaining them. It reports on the design and development of new integrated environments to support the construction and operation of persistent application systems, and on the principles employed to design, test, and implement such systems.

Phytochemistry, Computational Tools and Databases in Drug Discovery presents the state-of-the-art in computational methods and techniques for drug discovery studies from medicinal plants. Various tools and databases for virtual screening and characterization of plant bioactive compounds and their subsequent predictions on biological targets for the discovery of new drugs against specific diseases are presented, along with computational tools for the prediction of the toxic effects of phytochemicals on living systems. The book also provides in-depth insight on the applications of these computational tools as well as the databases that describe the interactions of phytochemicals with diseases along with predictions for druggable bioactive compounds. Useful for drug developers, medicinal chemists, toxicologists, phytochemists, plant biochemists and analytical chemists, this book clearly presents the various computational techniques, tools and databases for phytochemical research. - Provides the various databases, methods and procedures for computational drug discovery in plants - Includes insights into the predictors for properties of phytochemicals against different diseases - Discusses the applications of computational tools and their databases

This volume constitutes the proceedings of the 12th British National Conference on Databases (BNCOD-12), held at Surrey, Guildford in July 1994. The BNCOD conferences are thought as a platform for exchange between theoreticians and practitioners, where researchers from academia and industry meet professionals interested in advanced database applications. The 13 refereed papers presented in the proceedings were selected from 47 submissions; they are organized in chapters on temporal databases, formal approaches, parallel databases, object-oriented databases, and distributed databases. In addition there are two invited presentations: "Managing open systems now that the "Glashouse" has gone" by R. Baker and "Knowledge reuse through networks of large KBs" by P.M.D. Gray.