Heritable human genome editing - making changes to the genetic material of eggs, sperm, or any cells that lead to their development, including the cells of early embryos, and establishing a pregnancy - raises not only scientific and medical considerations but also a host of ethical, moral, and societal issues. Human embryos whose genomes have been edited should not be used to create a pregnancy until it is established that precise genomic changes can be made reliably and without introducing undesired changes - criteria that have not yet been met, says Heritable Human Genome Editing. From an international commission of the U.S. National Academy of Medicine, U.S. National Academy of Sciences, and the U.K.'s Royal Society, the report considers potential benefits, harms, and uncertainties associated with genome editing technologies and defines a translational pathway from rigorous preclinical research to initial clinical uses, should a country decide to permit such uses. The report specifies stringent preclinical and clinical requirements for establishing safety and efficacy, and for undertaking long-term monitoring of outcomes. Extensive national and international dialogue is needed before any country decides whether to permit clinical use of this technology, according to the report, which identifies essential elements of national and international scientific governance and oversight.

Thrust back into society after her divorce, Sophia's family issues rise to the surface once more. Unbeknown to Sophia, she is the cause of much unrest in London's criminal underworld. Capturing the interest of mob boss, Markus Falzon, Sophia becomes smitten by his dark and brooding ways. Soon, she will come to realise her true inheritance and her place in London's unlawful society, but a devastating price must be paid...

In this book the bestselling author and psychoanalyst Massimo Recalcati offers a fundamental re-examination of what ‘being a mother’ means today, in a world where new social and sexual freedoms mean that motherhood is no longer the sole destiny of women. Questioning the belief that a mother’s love is natural and unconditional, he paints a more complex and troubling picture of the mother–child relationship, observing that mothers may even resent their children as a result of unresolved conflicts between different dimensions of love. The mother’s hands not only nurture but can also potentially harm. Recalcati argues that it is precisely in these competing demands that motherhood fulfils its function: only if the mother is ‘not-all-mother’ can a child experience the absence that enables it to access the symbolic and cultural world. Recalcati cuts through conventional wisdom to offer a fresh perspective on the changing nature of motherhood today. An international bestseller, this book will appeal to a wide general readership, as well as to students and scholars of gender studies, psychoanalysis and related disciplines.

In contrast to the way inheritance is understood in scientific discourse and culture more broadly, inheritance in psychoanalysis is a paradox. Although it's impossible, strictly speaking, for the unconscious to be inherited, this volume demonstrates how the concept of inheritance can occasion a rich reassessment and reinvention of psychoanalytic theory and practice. The collection enacts a critical traversal of inheritance for psychoanalysis: from the most basic assumptions of natural or biological inheritance, such as innateness, heredity, evolution, and ontogenesis, to analysis of the ways cultural traditions can be challenged and transformed, and finally to the reinvention of psychoanalytic practice, in which the ethics of inheritance is fully realized as the individual's responsibility to transform the social bond. Featuring strong interdisciplinary analysis rooted in both psychoanalysis and philosophy, this volume further engages science, politics, and cultural studies, and addresses contemporary political challenges such as autism and transgenderism.

She’s suddenly inherited billions—and a captivating business rival! Catch the thrilling conclusion to USA TODAY bestselling author Rachel Bailey’s Marriages and Mergers series! Australian born-and-bred teacher Mae Dunstan just inherited billions. Now she’s in the United States to claim what’s hers. CEO Sebastian Newport wants to buy her out of the company that started a feud between their families. But Mae isn’t ready to trust the charismatic single father. His solution? Spend one week together. All bets are off when sparks in the boardroom lead to passion in the bedroom. Amid divided loyalties, open questions and a legacy about to come full circle, Mae’s affair with Sebastian could jeopardize more than the bottom line… Harlequin Desire transports you to the luxurious worlds of American tycoons, ranchers and family dynasties. Get ready for bold encounters and sizzling chemistry. You’ll be swept away by this bold, sizzling romance, part of the Marriages and Mergers series: Book 1: Overnight Inheritance