Dr. Richard Polin's Neonatology Questions and Controversies series highlights the most challenging aspects of neonatal care, offering trustworthy guidance on up-to-date diagnostic and treatment options in the field. In each volume, renowned experts address the clinical problems of greatest concern to today's practitioners, helping you handle difficult practice issues and provide optimal, evidence-based care to every patient. - Stay fully up to date in this fast-changing field with Infectious Disease and Pharmacology, an all-new volume in the series. - Thorough, up-to-date content on the epidemiology, clinical manifestations, treatment, and outcomes for neonatal-perinatal infections, including necrotizing enterocolitis, neonatal HSV, and congenital Zika virus infection. - The latest information on dosing of antibiotics, antivirals, and antifungals. - Current coverage of therapies for neonatal gastroesophageal reflux, seizures, neuroprotection, and neonatal abstinence syndrome, as well as pharmacokinetic and pharmacogenetic considerations in neonatal care. - Consistent chapter organization to help you find information quickly and easily. - The most authoritative advice available from world-class neonatologists who share their knowledge of new trends and developments in neonatal care. Purchase each volume individually, or get the entire 7-volume set!Gastroenterology and NutritionHematology, Immunology and GeneticsHemodynamics and CardiologyInfectious Disease and Pharmacology New Volume!Nephrology and Fluid/Electrolyte PhysiologyNeurologyThe Newborn Lung

The revised and up-to-date third edition of Drug Interactions in Infectious Diseases delivers a text that will enhance your clinical knowledge of the complex mechanisms, risks, and consequences of drug interactions associated with antimicrobials, infection, and inflammation. The third edition features five new chapters that cover material not addressed in previous editions. These new chapters describe interactions with a number of drug classes such as non-HIV antiviral, antimalarial, antiparasitic, antihelmintic, macrolide, azalide and ketolide agents. A novel chapter on probe cocktail studies has been included to highlight an important research tool for drug development. These chapters address material that cannot be retrieved easily in the medical literature. The highly acclaimed food-drug interactions as well as the study design and analysis chapters remain definitive references. The newly written drug-cytokine interaction highlights the need for our improved understanding of the complex interrelationship of acute infection, inflammation, and the risk of drug interactions. Informative tables on specific drug-drug interactions are provided throughout the chapters as a quick clinical resource. The Third Edition of Drug Interactions in Infectious Diseases is a distillation of relevant drug interactions associated with antimicrobials, infection, and inflammation. This concise review of the mechanisms and strategies to manage drug interactions should be valuable to all health care practitioners. Features • Definitive reference source of up-to-date information on antimicrobial drug interactions • Informative tables on the degree of interaction for specific antimicrobial agents • In-depth discussion of mechanisms and potential mechanistic pathways of interaction • New chapters on non-HIV antiviral, antimalarial, antiparasitic, and macrolide, azalide and ketolide agents • New chapter on probe-cocktail studies as a research tool to study drug-drug interactions • Inclusion of new antimicrobial agents and their associated drug interactions • First rate chapters on study design and analysis, and drug-food interactions • A fresh perspective on drug-cytokine interactions • Authoritative chapter on regulatory considerations of drug interactions during drug development

This book covers both the basic pharmacology and clinical pharmacotherapy of infectious diseases. All of the available pharmacotherapies used in the treatment of infectious diseases including antibiotics, antimycobacterials, antifungals, anthelminthics, antiprotozoals, antivirals, and immunizations are included in this text. Inside, you will find: -A thorough description of the mechanism of action, spectrum of coverage, common and serious adverse effects, and mechanisms of resistance to each drug group. -Clinical indications and contraindications of each drug as well as guideline-directed management of common bacterial, fungal, protozoal, helminth, and viral infections. -Tables that summarize the available formulations, brand names, and usual dosage regimens for both adult and pediatric patients, as well as dose-modifications for patients with kidney or liver disease. This book is intended for advanced undergraduate and graduate students taking courses devoted to infectious disease pharmacology ("bugs and drugs" courses), as well as medical/physician assistant students and residents that are training in infectious diseases or internal medicine.

Because of limited access to medical libraries and medical journals, the majority of clinicians may find it difficult to keep informed on the latest developments in drug manufacture and treatment of infectious diseases in immunocompromised patients. This new handbook strives to fulfill the need for information in this area of medicine. This is the first book on drug development and treatment of infectious diseases in immunocompromised hosts. It integrates both results from large-scale clinical trials and single cases as well as small groups of patients. It covers bacterial, viral, parasitic, and fungal infections, including a wide array of diseases. Infectious Diseases in Immunocompromised Hosts encompasses not only opportunistic infections associated exclusively with immunocompromised patients, but also common infections that become life-threatening for immunosuppressed individuals.

Select the most appropriate drug in any clinical situation--quickly and easily Developed for use at the point of care, Pharmacotherapy Bedside Guide helps you decide which pharmacotherapy to employ in specific clinical situations. Comprised exclusively of quick-hit tables and algorithms, this carryanywhere companion tells you what treatment the evidence suggests for each illness or disorder. It also details essential drug information, such as benefits, risks, adverse reactions, dosage, interactions with other drugs, and responses. Conveniently organized by specialty and disorder rather than drug, Pharmacotherapy Bedside Guide will prove invaluable when treating patients.

Infectious diseases are the leading cause of death globally, particularly among children and young adults. The spread of new pathogens and the threat of antimicrobial resistance pose particular challenges in combating these diseases. Major Infectious Diseases identifies feasible, cost-effective packages of interventions and strategies across delivery platforms to prevent and treat HIV/AIDS, other sexually transmitted infections, tuberculosis, malaria, adult febrile illness, viral hepatitis, and neglected tropical diseases. The volume emphasizes the need to effectively address emerging antimicrobial resistance, strengthen health systems, and increase access to care. The attainable goals are to reduce incidence, develop innovative approaches, and optimize existing tools in resource-constrained settings.