Science, as Andrew Goliszek proves in this compendious, chilling, and eye-opening book, has always had its dark side. Behind the bright promise of life-saving vaccines and life-enhancing technologies lies the true cost of the efforts to develop them. Knowledge has a price; often that price has been human suffering. The ethical limits governing use of the human body in experimentation have been breached, redefined, and breached again---from the moment the first plague-ridden corpse was heaved over the fortifications of a besieged medieval city to the use of cutting-edge gene therapy today. Those limits are in constant need of redefinition, for the goals and the techniques have become both more refined and more secretive. The German and Japanese human experiments of the 1930s and 1940s horrified the world when they came to light. These barbaric exercises in pseudoscience grew out of assumptions of racial superiority. The subjects were deemed subhuman; ordinary guidelines could therefore be suspended. What has happened in the decades since World War II has differed only in degree. Explicitly or implicitly, any organization or government that undertakes or sponsors scientific research applies some measure of human worth. Experimentation rests upon an equation that balances suffering against gain, the good of the collective against the rights of the individual, and the risk of unknown consequences against the rewards of scientific discovery. Everything depends upon who makes that equation. The sobering and gripping accumulation of evidence in this book proves exactly what has been justified in the name of science. The science of "eugenics" justified enforced sterilization. The need to gain an upper hand in the Cold War justified CIA experiments involving mind control and drugs. The desperate race to control nuclear proliferation was used to justify radiation experiments whose effects are still being felt today. Chemical warfare, gene therapy, molecular medicine: These subjects dominate headlines and even direct our government's foreign policy, yet the whole truth about the experimentation behind them has never been made public. Though not a cheering book, In the Name of Science is a crucially important one, and it deserves a wide audience. A biologist by training, Goliszek presents each topic clearly and explains fully its significance and implications. Connecting the history of scientific experimentation through time with the topics that are likely to dominate the future, he has performed an invaluable service. No other book on the market provides the research included here, or presents it with such persuasive force.

Fair, witty appraisal of cranks, quacks, and quackeries of science and pseudoscience: hollow earth, Velikovsky, orgone energy, Dianetics, flying saucers, Bridey Murphy, food and medical fads, and much more.

Few arguments in biomedical experimentation have stirred such heated debate in recent years as those raised by animal research. In this comprehensive analysis of the social, political, and ethical conflicts surrounding the use of animals in scientific experiments, Barbara Orlans judges both ends of the spectrum in this debate -- unconditional approval or rejection of animal experimentation -- to be untenable. Instead of arguing for either view, she thoughtfully explores the ground between the extremes, and convincingly makes the case for public policy reforms that serve to improve the welfare of laboratory animals without jeopardizing scientific endeavor. This book presents controversial issues in a balanced manner based on careful historical analysis and original research. Different mechanisms of oversight for animal experiments are compared and those that have worked well are identified. This compelling work will be of interest to biomedical scientists, ethicists, animal welfare advocates and other readers concerned with this critical issue.

From a New York Times bestselling author comes the gripping, untold history of science's darkest secrets, "a fascinating book [that] deserves a wide audience" (Publishers Weekly, starred review). Science is a force for good in the world—at least usually. But sometimes, when obsession gets the better of scientists, they twist a noble pursuit into something sinister. Under this spell, knowledge isn’t everything, it’s the only thing—no matter the cost. Bestselling author Sam Kean tells the true story of what happens when unfettered ambition pushes otherwise rational men and women to cross the line in the name of science, trampling ethical boundaries and often committing crimes in the process. The Icepick Surgeon masterfully guides the reader across two thousand years of history, beginning with Cleopatra’s dark deeds in ancient Egypt. The book reveals the origins of much of modern science in the transatlantic slave trade of the 1700s, as well as Thomas Edison’s mercenary support of the electric chair and the warped logic of the spies who infiltrated the Manhattan Project. But the sins of science aren’t all safely buried in the past. Many of them, Kean reminds us, still affect us today. We can draw direct lines from the medical abuses of Tuskegee and Nazi Germany to current vaccine hesitancy, and connect icepick lobotomies from the 1950s to the contemporary failings of mental-health care. Kean even takes us into the future, when advanced computers and genetic engineering could unleash whole new ways to do one another wrong. Unflinching, and exhilarating to the last page, The Icepick Surgeon fuses the drama of scientific discovery with the illicit thrill of a true-crime tale. With his trademark wit and precision, Kean shows that, while science has done more good than harm in the world, rogue scientists do exist, and when we sacrifice morals for progress, we often end up with neither.

*Shortlisted for the 2019 Royal Society Insight Investment Science Book Prize* One of the most fascinating scientific detective stories of the last fifty years, an exciting quest for a new form of matter. “A riveting tale of derring-do” (Nature), this book reads like James Gleick’s Chaos combined with an Indiana Jones adventure. When leading Princeton physicist Paul Steinhardt began working in the 1980s, scientists thought they knew all the conceivable forms of matter. The Second Kind of Impossible is the story of Steinhardt’s thirty-five-year-long quest to challenge conventional wisdom. It begins with a curious geometric pattern that inspires two theoretical physicists to propose a radically new type of matter—one that raises the possibility of new materials with never before seen properties, but that violates laws set in stone for centuries. Steinhardt dubs this new form of matter “quasicrystal.” The rest of the scientific community calls it simply impossible. The Second Kind of Impossible captures Steinhardt’s scientific odyssey as it unfolds over decades, first to prove viability, and then to pursue his wildest conjecture—that nature made quasicrystals long before humans discovered them. Along the way, his team encounters clandestine collectors, corrupt scientists, secret diaries, international smugglers, and KGB agents. Their quest culminates in a daring expedition to a distant corner of the Earth, in pursuit of tiny fragments of a meteorite forged at the birth of the solar system. Steinhardt’s discoveries chart a new direction in science. They not only change our ideas about patterns and matter, but also reveal new truths about the processes that shaped our solar system. The underlying science is important, simple, and beautiful—and Steinhardt’s firsthand account is “packed with discovery, disappointment, exhilaration, and persistence...This book is a front-row seat to history as it is made” (Nature).

We are accustomed to thinking of science and its findings as universal. After all, one atom of carbon plus two of oxygen yields carbon dioxide in Amazonia as well as in Alaska; a scientist in Bombay can use the same materials and techniques to challenge the work of a scientist in New York; and of course the laws of gravity apply worldwide. Why, then, should the spaces where science is done matter at all? David N. Livingstone here puts that question to the test with his fascinating study of how science bears the marks of its place of production. Putting Science in Its Place establishes the fundamental importance of geography in both the generation and the consumption of scientific knowledge, using historical examples of the many places where science has been practiced. Livingstone first turns his attention to some of the specific sites where science has been made—the laboratory, museum, and botanical garden, to name some of the more conventional locales, but also places like the coffeehouse and cathedral, ship's deck and asylum, even the human body itself. In each case, he reveals just how the space of inquiry has conditioned the investigations carried out there. He then describes how, on a regional scale, provincial cultures have shaped scientific endeavor and how, in turn, scientific practices have been instrumental in forming local identities. Widening his inquiry, Livingstone points gently to the fundamental instability of scientific meaning, based on case studies of how scientific theories have been received in different locales. Putting Science in Its Place powerfully concludes by examining the remarkable mobility of science and the seemingly effortless way it moves around the globe. From the reception of Darwin in the land of the Maori to the giraffe that walked from Marseilles to Paris, Livingstone shows that place does matter, even in the world of science.