Containing thousands of entries of both vernacular and scientific names of Great Plains plants, the literature that informs this exhaustive listing spans nearly 300 years. Author Elaine Nowick has drawn from sources as diverse as Linnaeus, Lewis and Clark, and local university extension publications to compile the gamut of practical, and often fanciful, common plant names used over the years. Each common name is accompanied by a definitive scientific name with references and authority information. Interspersed with scientifically-correct botanical line drawings, the entries are written in standard ICBN format, making this a useful volume for scholars as well as lay enthusiasts alike. Volume 1 presents, in alphabetical order, all the historical common names of plants recorded in Great Plains flora, herbaria, and botanical collections, together with the scientific names of species to which those common names have been applied.

The dictionary contains about 30,000 vernacular and literary English names of plants (plus a few American), both wild and cultivated, with their botanical name and a brief account of the names' meaning if known. It was conceived as part of the author's wider interest in plant and tree lore, and ethnobotanical studies. Knowledge of plant names can give insight into largely forgotten beliefs. Why for example is, or was, the common red poppy known as "Blind Man"? An old superstition has it that if the poppy were put to the eyes it would cause blindness. Such names were probably the result of some taboo against picking the plant. Similarly, other names were likely to have been applied as a result of a country mother's warning to her children against eating poisonous berries. For the warning carries more weight when the name given to the berry reinforces the warning. Many such plants or fruits may be ascribed to the devil, Devil's Berries for Deadly Nightshade is an example. Names may also be purely descriptive, and can also serve to explain the meaning of the botanical name. Beauty-Berry is an example: it is the name given to the American shrub that belongs to the genus Callicarpa, which is made up of two Greek words that mean beauty and berry. Literary, or "book" names, have also been included in this dictionary, as being a very important part of the whole. Many of them provide links in the transmission of words through the ages. Thor's Beard, for example, is a book name for "houseleek", and has never been used in the dialect. But it highlights the legend that houseleek is a lightning plant, and by reverse logic is a preserver from fire.