The opioid crisis in the United States has come about because of excessive use of these drugs for both legal and illicit purposes and unprecedented levels of consequent opioid use disorder (OUD). More than 2 million people in the United States are estimated to have OUD, which is caused by prolonged use of prescription opioids, heroin, or other illicit opioids. OUD is a life-threatening condition associated with a 20-fold greater risk of early death due to overdose, infectious diseases, trauma, and suicide. Mortality related to OUD continues to escalate as this public health crisis gathers momentum across the country, with opioid overdoses killing more than 47,000 people in 2017 in the United States. Efforts to date have made no real headway in stemming this crisis, in large part because tools that already existâ€"like evidence-based medicationsâ€"are not being deployed to maximum impact. To support the dissemination of accurate patient-focused information about treatments for addiction, and to help provide scientific solutions to the current opioid crisis, this report studies the evidence base on medication assisted treatment (MAT) for OUD. It examines available evidence on the range of parameters and circumstances in which MAT can be effectively delivered and identifies additional research needed.

Drug overdose, driven largely by overdose related to the use of opioids, is now the leading cause of unintentional injury death in the United States. The ongoing opioid crisis lies at the intersection of two public health challenges: reducing the burden of suffering from pain and containing the rising toll of the harms that can arise from the use of opioid medications. Chronic pain and opioid use disorder both represent complex human conditions affecting millions of Americans and causing untold disability and loss of function. In the context of the growing opioid problem, the U.S. Food and Drug Administration (FDA) launched an Opioids Action Plan in early 2016. As part of this plan, the FDA asked the National Academies of Sciences, Engineering, and Medicine to convene a committee to update the state of the science on pain research, care, and education and to identify actions the FDA and others can take to respond to the opioid epidemic, with a particular focus on informing FDA's development of a formal method for incorporating individual and societal considerations into its risk-benefit framework for opioid approval and monitoring.

Illicit drugs, despite the “war” waged by the United States government, remain a tremendous drain on the American economy and continue to take their toll on the lives of countless Americans. A comprehensive text with an instructor's manual, Drug Abuse and Social Policy in America analyzes why current US policy on the use of licit and illicit mood-altering drugs has failed. This groundbreaking book addresses differences between decriminalization, legalization, and “zero tolerance”--areas and philosophies that are poorly understood--and suggests a multipronged approach to diminish inappropriate drug use. Physicians, health care providers, teachers, law enforcement officers, policymakers, social service providers, and students of public policy and health will gain a better understanding of substance abuse as a societal problem, rather than an individual problem, and see that the billions of dollars spent on law enforcement would be better spent on education, prevention, treatment, and providing alternatives to drug use.Currently the leading risk factor associated with the transmission of HIV, illicit drugs continue to destroy the fabric of life in many inner-city communities. Yet, drugs are a problem for Americans from every corner of society, from suburban teenagers to pro athletes to homeless people. Author Barry Stimmel demonstrates in Drug Abuse and Social Policy in America that the drug problem is not being addressed adequately because of a lack of commitment from the majority of Americans and government leaders. The issues Drug Abuse and Social Policy in America asks readers to confront include: Why do we provide insufficient treatment facilities and incarcerate users, yet wonder why more prison space is needed? Why do we readily agree to build more prisons rather than community centers that provide alternatives for youths? Why are we concerned with teenage smoking and drinking, yet allow advertising of these substances? Why do we advocate rehabilitation, but not hire people in recovery? Why do we ask pregnant women with drug problems to seek help, then try to take custody of their children rather than provide social support while they receive treatment?Drug Abuse and Social Policy in America challenges academics, practitioners, and future social service providers and policymakers to rethink their entire conception of the problem of substance abuse in America with a cutting question: “Have we made any substantial progress in diminishing the sue of nicotine, the excessive consumption of alcohol, or the inappropriate use of prescription drugs, all of which are responsible for more illnesses and societal costs than all illicit drugs combined?” Identifying this as the place where all efforts to curb drug use must start, Drug Abuse and Social Policy in America offers readers many ways that individuals, communities, organizations, and society can take action and be more effective in convincing both those who consume drugs and those who profit from their sale that their actions are inappropriate and unacceptable.