This book comprises 96 peer-reviewed contributions submitted to the 10th ICAM Congress, held in Trondheim, Norway on 01-05 August 2011. Themes covered include: 1) Advanced materials, including high-performance technical ceramics and glasses, 2) Analytical techniques, instrumentation and automation, 3) Bio-mimetic mineral materials, medical mineralogy, 4) Construction materials including cement/SCMs, concrete, bricks, tiles, screeds, 5) Cultural heritage, stone artifacts and preservation, 6) Environment and energy mineralogy, including CO2 sequestration, 7) Geometallurgy and process mineralogy, and 8) Industrial minerals including gems, ore minerals, and mineral exploration.

Mexico's Spiritual Reconquest brings to life a classically misunderstood pícaro: liberal soldier turned Catholic priest and revolutionary antipope, "Patriarch" Joaquín Pérez. Historian Matthew Butler weaves Pérez's controversial life story into a larger narrative about the relationship between religion, the state, and indigeneity in twentieth-century Mexico. Mexico's Spiritual Reconquest is at once the history of an indigenous reformation and a deeply researched, beautifully written exploration of what can happen when revolutions try to assimilate powerful religious institutions and groups. The book challenges historians to reshape baseline assumptions about modern Mexico in order to see a revolutionary state that was deeply vested in religion and a Cristero War that was, in reality, a culture clash between Catholics.

The immunological synapse (IS) is a specialised cell-cell adhesion that mediates antigen acquisition and regulates the activation of lymphocytes. Initial studies of the IS showed a structure composed of stable supra-molecular activation clusters (SMAC) organised during the interaction of helper T lymphocytes with B lymphocytes, working as antigen presenting cells. A central SMAC of coalesced T cell receptors (TCRs) and a peripheral SMAC for cell-cell adhesion were observed. IS with similar structure was later described during antigen acquisition by B cells and during the interaction of NK cells with target and healthy cells. More recent research developed with microscopy systems that improve the spatial and temporal resolution has showed the complex molecular dynamics at the IS that governs lymphocyte activation. Currently, the IS is seen as a three-dimensional structure where signalling networks for lymphocyte activation and endosomal and cytoskeleton machinery are polarised. A view has emerged in which dynamic microclusters of signalling complexes are composed of molecular components attached to the plasma membrane and other components conveyed on sub-synaptic vesicles transported to the membrane by cytoskeletal fibers and motor proteins. Much information is nonetheless missing about how the dynamics of the endosomal compartment, the cytoskeleton, and signalling complexes are reciprocally regulated to achieve the function of lymphocytes. Experimental evidence also suggests that the environment surrounding lymphocytes exposed to different antigenic challenge regulates IS assembly and functional output, making an even more complex scenario still far from being completely understood. Also, although some signalling molecular components for lymphocyte activation have been identified and thoroughly studied, the function of other molecules has not been yet uncovered or deeply characterised. This research topic aims to provide the reader with the latest information about the molecular dynamics governing lymphocyte activation. These molecular dynamics dictate cell decisions. Thus, we expect that understanding them will provide new avenues for cell manipulation in therapies to treat different immune-related pathologies.

This book serves as a source of information to facilitate the reading of the literature and the planning of trials. Supplies in one place all the information on this active and complex research topic and may stimulate more research that can lead to more exchanges between the laboratory, the clinical ward and the operating room. Fills the need of surgeons to understand the molecular mechanisms in hepatology. Provides a quick and comprehensive overview.

This landmark publication distills the body of knowledge that characterizes mineral processing and extractive metallurgy as disciplinary fields. It will inspire and inform current and future generations of minerals and metallurgy professionals. Mineral processing and extractive metallurgy are atypical disciplines, requiring a combination of knowledge, experience, and art. Investing in this trove of valuable information is a must for all those involved in the industry—students, engineers, mill managers, and operators. More than 192 internationally recognized experts have contributed to the handbook’s 128 thought-provoking chapters that examine nearly every aspect of mineral processing and extractive metallurgy. This inclusive reference addresses the magnitude of traditional industry topics and also addresses the new technologies and important cultural and social issues that are important today. Contents Mineral Characterization and AnalysisManagement and ReportingComminutionClassification and WashingTransport and StoragePhysical SeparationsFlotationSolid and Liquid SeparationDisposalHydrometallurgyPyrometallurgyProcessing of Selected Metals, Minerals, and Materials

Diabetes and cardiovascular disease together account for the largest portion of health care spending compared to all other diseases in Western society. This work seeks to provide an understanding of the causes of diabetes and its cardiovascular complications. As this understanding becomes more widely appreciated, it will serve as a foundation for evidence-based care and wider acceptance of sound science. The International Conference on Diabetes and Cardiovascular Disease, held in Winnipeg, in June 1999, was organized to bring together a multi-disciplinary group of researchers dedicated to further knowledge amongst researchers, care givers, and the managers of the health system. The invited speakers submitted their works for publication, which serves as the basis for this book. Major themes include: epidemiology of diabetes mellitus, metabolic risk factors in diabetes and cardiovascular disease, hypertension in diabetes mellitus, cardiac function in diabetes, glycemic control and improved cardiovascular function, diabetes management, and endothelial function in diabetes.