This is an official publication of the Indian Academy of Pediatrics. Several luminaries in the field of Pediatric Nephrology, from home and abroad, have contributed their might in bringing out this book. The book has been designed with a practical approach to renal problems in children, faced by treating clinicians in their routine pediatric practice. The book has been kept concise with simple language, making it more reader friendly. The book has 29 chapters, dealing with basic renal functions, common renal conditions in day to day pediatric practice and some of the more complex renal problems in children. Drug dosing guidelines for commonly used drugs in renal failure and a few useful appendices are also incorporated. The two color format will be pleasing to the eye and will facilitate easy reading by highlighting boxes, tables and key messages. The book is ideally suited to the needs of pediatricians, pediatric nephrologists, post graduate students, nephrologists and urologists interested in pediatric aspects of the discipline. Book jacket.

This new edition presents the latest developments in paediatric nephrology. Divided into fourteen sections, the book begins with an introduction to the basics of nephrology and the physiology of fluids, electrolytes and minerals, followed by renal evaluation and clinical syndromes. The following sections provide detailed coverage of the diagnosis and management of different renal disorders that may be encountered in children, including chronic kidney disease and acute kidney injury. Three chapters are dedicated to neonatal nephrology and the final section covers topics such as urinary tract infection, rickets and infectious diseases and the kidney. The second edition has been fully updated and features nearly 400 images, illustrations and tables to enhance learning. The extensive author team includes contributors from Connecticut, North Carolina, Missouri and Great Ormond Street Hospital, London. Key points Fully revised, new edition presenting latest developments in paediatric nephrology Fourteen sections cover diagnosis and treatment of numerous kidney disorders Includes section on neonatal nephrology Previous edition published in 2004

1. Critical Care Scenario in India 2. Recognition and Stabilization of the Critically Ill Child 3. Resuscitation 4. Fluid and Electrolytes in the Critically Ill Child 5. Oxygen Therapy in the Emergency Room and PICU 6. Lung Mechanics with Ventilation: Physiology and Monitoring 7. Basics of Mechanical Ventilation 8. Noninvasive Ventilation 9. Respiratory Monitoring in Pediatric Intensive Care Unit 10. Acute Respiratory Distress Syndrome 11. Hemodynamic Monitoring 12. Acute Heart Failure 13. Cardiac Arrhythmias 14. Vasoactive Agents 15. Hypertensive Crises 17. Approach to a Comatose Child 18. Head Injury in Children 19. Status Epilepticus 20. End of Life Care in the Pediatric Intensive Care Unit 21. Diabetic Ketoacidosis in Children 22. Basics of RRT in ICU 23. Gastrointestinal Tract Bleed 24. Acute Liver Failure 25. Pre- and Post-operative Management of a Liver Transplant Patient 26. Nutrition in Critically Ill Children 27. Dengue in Pediatric Intensive Care Unit 28. Management of a Child with Polytrauma 29. Drowning 30. Pediatric Emergency Care: Poisoning and Toxidromes 31. Envenomation (Snake Envenomation and Scorpion Sting) 32. Oncological Emergencies 33. Blood Components in Intensive Care Practice 34. Ventilator Associated Pneumonia and Hospital Acquired Pneumonia 35. Catheter-Related Blood Stream Infection 36. Catheter Associated Urinary Tract Infection 37. Antimicrobial Stewardship in PICU 38. Pain and Sedation 39. Nursing Issues in the PICU 40. Extracorporeal Membrane Oxygenation Index

SECTION I: BASICS OF MICROBIOLOGY AND PHARMACOLOGY 1. Rational Antimicrobial Therapy: Need of the Hour 2. Basics of Microbiologic Diagnosis 3. Antimicrobial Resistance: Current Scenario 4. Pharmacokinetics and Pharmacodynamics of Antimicrobials 5. Penicillins and Monobactams 6. Cephalosporins 7. Carbapenems 8. Beta-lactam and Beta-lactamase Inhibitor Combinations 9. Aminoglycosides 10. Macrolides and Azalides 11. Quinolones 12. Glycopeptides, Lipopeptides, Oxazolidinones, and Glycolipopeptides 13. Polymyxins, Newer Tetracyclines and Fosfomycin 14. Miscellaneous Antibacterial Drugs SECTION II: ANTIMICROBIAL THERAPY OF INFECTIONS 15. General Principles of Antimicrobial Therapy 16. Practicing Rational Antimicrobial Therapy 17. Antimicrobial Therapy in Acute Gastroenteritis 18. Antimicrobial Therapy in Intra-abdominal Infections 19. Antimicrobial Therapy in Upper Respiratory Tract Infections 20. Antimicrobial Therapy in Lower Respiratory Tract Infections 21. Antitubercular Therapy 22. Antimicrobial Therapy in Enteric Fever 23. Antimicrobial Therapy in Urinary Tract Infections 24. Antimicrobial Therapy in Skin and Soft Tissue Infections 25. Antimicrobial Therapy in Skeletal Infections 26. Antimicrobial Therapy in Central Nervous System Infections 27. Antimicrobial Therapy in Infective Endocarditis 28. Antimicrobial Therapy in Neonatal Sepsis 29. Antimicrobial Therapy in Septic Shock 30. Antimicrobial Therapy of Healthcare-associated Infections 31. Antimicrobial Therapy in Febrile Neutropenia 32. Antimicrobial Prophylaxis 33. Antimalarial Therapy 34. Antiretroviral Therapy 35. Anthelminthic Therapy 36. Antiviral Therapy 37. Antifungal Therapy 38. Antimicrobial Therapy of Assorted Infections SECTION III: CASE SCENARIOS OF ANTIMICROBIAL THERAPY 39. Rational Antimicrobial Therapy--Illustrative Cases SECTION IV: READY RECKONER FOR ANTIMICROBIAL DRUGS 40. Antimicrobial Formulary Index

This second edition brings paediatricians and trainees fully up to date with the latest developments in the rapidly changing field of paediatric cardiology. Beginning with clinical assessment and diagnostic tools such as chest X-Ray and ECG, the following chapters discuss different disorders and diseases encountered in children, from hypertension and arrhythmias, to rheumatic fever, myocardial disease and Kawasaki disease. The final section provides dosages for numerous drugs. The new edition has been fully updated and includes more than 200 images, illustrations and tables to enhance learning. Each chapter includes an extensive reference section or suggested reading for further information. Key points New edition presenting latest developments in paediatric cardiology Covers diagnostic tools, and numerous diseases and disorders Final section presents detailed drug dosage information Previous edition published in 2008