Considers the theatrical fortunes of Richard II from its politically controversial beginnings on the Elizabethan and Restoration stage, to its various later interpretations responding to 19th- and 20th-century tastes and attitudes. A wide range of performances is documented and discussed. These illustrate the ways in which different theatres and companies have staged the play by cutting, restructuring or adding to Shakepeare's script to highlight spectacle, the personality of the King, the nature of authority and the place of Richard in the overall sweep of English history.

Presents a biography of Karol Wojtyla, including his boyhood in Poland, his steps to the papacy, and his twenty-five years as Pope John Paul II.

The collection of thirteen codices found in upper Egypt near Nag Hammadi in 1946 is one of the major archaeological discoveries of our time. Apparently the library of a Gnostic community in late antiquity, the codices are a repository of important spiritual materials from throughout the ancient world. Hence a thorough analysis of this new material is indispensable for any proper understanding of the history of religions in this period. The rich documentation which the codices add to early Coptic text material promises to raise to a new precision the historical analysis of that language.|This edition presents collotype reproductions in natural size of all folios of the thirteen codices as well as reproductions of the covers and photographs previously taken of fragments that are now lost.

In The Problem of the Idea of Culture in John Paul II: Exposing the Disruptive Agency of the Philosophy of Karol Wojtyła, John Corrigan provides a new lens with which to view and understand the philosophy of Karol Wojtyła/John Paul II. He exposes Wojtyła as a major player in contemporary philosophical debates. The work reformulates the “problem of experience” in light of the questions surrounding our idea of culture. Corrigan argues that for Wojtyła the drama of the “problem of experience” manifests in the apparently divergent accounts of the meaning of human experience as presented by the philosophies of being and of consciousness. Solving this conundrum results in an idea of the person capable of explaining human experience in relation to human culture,unfolding the experiences of self-knowledge, conscience, and the ontic-causal relationship of the person to human culture. The first part of the book concerns formal considerations regarding the constitutive aspects of Wojtyła’s approach, while the second part deals with pragmatic considerations drawn from his comments on culture.

Reliably optimizing a new treatment in humans is a critical first step in clinical evaluation since choosing a suboptimal dose or schedule may lead to failure in later trials. At the same time, if promising preclinical results do not translate into a real treatment advance, it is important to determine this quickly and terminate the clinical evaluation process to avoid wasting resources. Bayesian Designs for Phase I–II Clinical Trials describes how phase I–II designs can serve as a bridge or protective barrier between preclinical studies and large confirmatory clinical trials. It illustrates many of the severe drawbacks with conventional methods used for early-phase clinical trials and presents numerous Bayesian designs for human clinical trials of new experimental treatment regimes. Written by research leaders from the University of Texas MD Anderson Cancer Center, this book shows how Bayesian designs for early-phase clinical trials can explore, refine, and optimize new experimental treatments. It emphasizes the importance of basing decisions on both efficacy and toxicity.

This report aims to provide an in-depth analysis of teachers’ and school leaders’ perceptions of the value of their profession, their work-related well-being and stress, and their satisfaction with their working conditions. It also offers a description of teachers’ and school leaders’ contractual arrangements, opportunities to engage in professional tasks such as collaborative teamwork, autonomous decision making, and leadership practices.

Volume II of this two-volume text and reference work concentrates on the applications of probability theory to statistics, e.g., the art of calculating densities of complicated transformations of random vectors, exponential models, consistency of maximum estimators, and asymptotic normality of maximum estimators. It also discusses topics of a pure probabilistic nature, such as stochastic processes, regular conditional probabilities, strong Markov chains, random walks, and optimal stopping strategies in random games. Unusual topics include the transformation theory of densities using Hausdorff measures, the consistency theory using the upper definition function, and the asymptotic normality of maximum estimators using twice stochastic differentiability. With an emphasis on applications to statistics, this is a continuation of the first volume, though it may be used independently of that book. Assuming a knowledge of linear algebra and analysis, as well as a course in modern probability, Volume II looks at statistics from a probabilistic point of view, touching only slightly on the practical computation aspects.