The book gives a review of the state-of-the-art of recent investigations of the adipositas diabetes syndrome of sand rats kept under laboratory conditions and given various diet regimes. Measurements of specific activities and flux rates in carbohydrate and fat metabolism determined by different analytical methods in vitro and in vivo provide insights into the pathophysiology and pathobiochemistry of different forms of the diabetic syndrome which cannot be obtained in humans.

Diabetes mellitus is a very common disease which affects approximately 150,000,000 worldwide. With its prevalence rising rapidly, diabetes continues to mystify and fascinate both practitioners and investigators by its elusive causes and multitude of This textbook is written for endocrinologists, specialists in other disciplines who treat diabetic patients, primary care physicians, housestaff and medical students. It covers, in a concise and clear manner, all aspects of the disease, from its pathogenesis on the molecular and cellular levels to its most modern therapy.

Proceedings of the First International Meeting of the Pancreatic Islet Study Group held in the Alicante, Spain, November 25-28 1994