Since the subject of high dilution effects is still a subject for debate, this volume provides evidence in support of effects from control clinical studies, clinical records from veteran physicians, controlled experiments on animals and plants, and in vitro tests without any organisms (Chapter II). An overview of the methods for preparing drugs at ultra high dilution is also provided as well as the basic principles of homeopathy, which has been alleviating human suffering through the use of these drugs for several hundred years (Chapter I). Chapter III provides physical basis of high dilutions as evidence from the NMR, IR, UV and fluorescence spectra of those drugs. Since water is used as the diluents media, the structure and dynamics of water polymers in relation to high dilution are discussed in order to facilitate easy comprehension of this physical aspect, the basic principles of spectroscopy are also described. Chapter IV focuses on the mechanism of action of potentized drugs in the living system, discussing the structure of the cell, the plasma membrane, the integral proteins on the membrane, the interaction between these proteins and high dilutions and the manifestations of the therapeutic effects of high dilutions. Some aspects, peculiar to homeopathy, such as the chief miasm psora, and the literalities and time modalities of symptoms and drug action are interpreted from a scientific perspective. Chapter IV ends with a brief discussion on water structures and the origin of life to show the natural evolution of high dilution effects. The book not only helps in understanding the physical basis of high dilutions and their mechanism of action in organisms but provides many new avenues of investigation into this interdisciplinary field of science.

While evidence for the biological effects of high dilutions (above Avogadro’s number) has been extensively documented since the 1980s, it seems to remain invisible to part of the global scientific community. This book provides investigators and other interested readers with direct access to the latest research, conducted between 2009 and 2019, by members of the Groupe International de Recherche sur l’Infinitésimal, the first international scientific society devoted to scientific studies of high dilutions. As shown here, the state of the art in high dilution research allows answering with a sound, evidence-based “no” to the question “Is homeopathy really that implausible?” Therefore this book is an essential contribution to the ongoing debate on complementary and alternative medicine, much-needed by practitioners, patients, and governments in the formulation of healthcare policies.

Polymer Science and Innovative Applications: Materials, Techniques, and Future Developments introduces the science of innovative polymers and composites, their analysis via experimental techniques and simulation, and their utilization in a variety of application areas. This approach helps to unlock the potential of new materials for product design and other uses. The book also examines the role that these applications play in the human world, from pollution and health impacts, to their potential to make a positive contribution in areas including environmental remediation, medicine and healthcare, and renewable energy. Advantages, disadvantages, possibilities, and challenges relating to the utilization of polymers in human society are included. - Presents the latest advanced applications of polymers and their composites and identifies key areas for future development - Introduces the simulation methods and experimental techniques involved in the modification of polymer properties, supported by clear and detailed images and diagrams - Supports an interdisciplinary approach, enabling readers across different fields to harness the power of new materials for innovative applications

The SAGE Encyclopedia of Pharmacology and Society explores the social and policy sides of the pharmaceutical industry and its pervasive influence in society. While many technical STM works explore the chemistry and biology of pharmacology and an equally large number of clinically oriented works focus on use of illegal drugs, substance abuse, and treatment, there is virtually nothing on the immensely huge business (“Big Pharma”) of creating, selling, consuming, and regulating legal drugs. With this new Encyclopedia, the topic of socioeconomic, business and consumer, and legal and ethical issues of the pharmaceutical industry in contemporary society around the world are addressed. Key Features: 800 signed articles, authored by prominent scholars, are arranged A-to-Z and published in a choice of electronic or print formats Although arranged A-to-Z, a Reader's Guide in the front matter groups articles by thematic areas Front matter also includes a Chronology highlighting significant developments in this field All articles conclude with Further Readings and Cross References to related articles Back matter includes an annotated Resource Guide to further research, a Glossary, Appendices (e.g., statistics on the amount and types of drugs prescribed, etc.), and a detailed Index The Index, Reader’s Guide, and Cross References combine for search-and-browse capabilities in the electronic edition The SAGE Encyclopedia of Pharmacology and Society is an authoritative and rigorous source addressing the pharmacology industry and how it influences society, making it a must-have reference for all academic libraries as a source for both students and researchers to utilize.

Mercury is widespread in our environment. Methylmercury, an organic form of mercury, can accumulate in the aquatic food chain and lead to high concentrations in predatory fish. When consumed by humans, contaminated fish represent a public health risk. Toxic Effects of Mercury intends to facilitate among its readers the understanding of the importance of mercury pollution in the environment and the health consequences associated with exposure to this metal. The knowledge on methylmercury (MeHg) toxicity collected over the years is undoubtedly robust creating an impression all that is to be learnt about this metal has already been accomplished. However, in large measure, past knowledge has merely laid the ground for interesting questions that have yet to be fully addressed and concepts have yet to be deciphered. One of my major goals was to make a valiant attempt to include state-of-the-art information on the mechanisms of mercury toxicity, describing its effects on cultured cellular systems as well as in whole living organisms, starting from the lessons learned from the tragic events in Minamata Bay, Japan. A special focus of the book is on the neurotoxic effects of MeHg. An understanding at the cellular level is necessary to gather information on the structural and functional alterations induced by MeHg and how they possibly become unmasked and evident at the behavioral level, 32 chapters of the book have been organised having these considerations in mind. This book will provide state-of-the-art information to the graduate students training in toxicology, risk assessors, researchers and medical providers at large. It is aimed to bring the readers updated information on contemporary issues associated with exposure to methylmercury, from its effects on stem cells and neurons to population studies. It is a valuable resource for individuals interested in the public health effects and regulation of mercury. The report provides an excellent example of the implications of decisions in the risk assessment process for a larger audience and is written with the hope that the information will provide better understanding of the mercury problems which confront us.

High dilution effects constitute a major problem on the frontier of biophysics. The reported effects on simple and complex biological systems range from in vitro and in vivo models to cellular metabolism regulation, the immune system, the nervous system, intoxicated organs and organisms, and developmental models. The physical properties of high dilutions have been considered, such as the organization properties of water molecules in the presence and after the presence of solute molecules, the energy characteristics of empty and full water clusters, and their dynamical interactions with proteins. Among the mechanisms responsible for the high dilution effects, a non-molecular transfer of information has been hypothesized.