This issue of Surgical Oncology Clinics of North America, edited by Dr. Lawrence Wagman, is devoted to Hepatocellular Cancer, Cholangiocarcinoma, and Metastatic Tumors of the Liver. Articles in this issue include: Epidemiology of Hepatomas; Risk Modeling: disease prevalence, outcome from treatment; Imaging; Resection techniques; Ablation techniques; Complications of interventions; Trans-arterial chemo-embolization (TACE); Continuous hepatic artery infusion (CHAI); Selective interstitial radiation therapy (SIRT) and External beam radiation therapy (EBRT); Systemic chemotherapy of HCC and Cholangiocarcinoma; and Systemic chemotherapy and CRC metastases.

This issue of Surgical Oncology Clinics of North America is devoted to "Biliary Tract and Primary Liver Tumors" and is edited by Timothy Pawlik, MD, of the Johns Hopkins Hospital in Baltimore. Expert authors in this issue review this topic in articles such as: Epidemiology and Risk Factors of Biliary Tract Tumors and Primary Liver Tumors; Imaging of the Patient with a Biliary Tract or Primary Liver Tumor; Percutaneous and Endoscopic Approaches to Biliary Tract Tumors and Primary Liver Tumors; Intrahepatic Cholangiocarcinoma; Hilar Cholangiocarcinoma; Distal Cholangiocarcinoma; Hepatocellular Carcinoma; Staging of Biliary Tract and Primary Liver Tumors; Intra-arterial Therapies: Primary Liver Tumors; Radiotherapy: Primary Liver Tumors; Systemic and Targeted Therapy; and Palliation: Treating Patients with Inoperable Biliary Tract and Primary Liver Tumors.

This issue of Surgical Oncology Clinics of North America focuses on Biliary Tract and Primary Liver Tumors and is edited by Dr. T. Clark Gamblin. Articles will include: Biliary Tract and Primary Liver Tumors; Biliary Tract and Primary Liver Tumors: Who, What and Why?; Imaging Updates for Biliary Tract or Primary Liver Tumors; Endoscopic and Percutaneous Approaches to Treat of Biliary Tract and Primary Liver Tumors: Controversies and Advances; Intrahepatic Cholangiocarcinoma: Strategies and Options; Surgical Considerations of Hilar Cholangiocarcinoma; Gall Bladder Cancer: Managing the Incidental Diagnosis; Approaches and Outcomes to Distal Cholangiocarcinoma; Evolving Surgical Options of Hepatocellular Carcinoma; Staging of Biliary and Primary Liver Tumors: Current Reccomendations and Workup; Systemic and Targeted Therapy for Biliary Tract Tumors and Primary Liver Tumors; Regional Chemotherapy for Biliary Tract and Primary Liver Cancer; Role of Radioembolization for Biliary Tract and Primary Liver Cancer; Inoperable Biliary Tract and Primary Liver Tumors: Palliative Treatment Options; Expanding the Surgical Pool for Hepatic Resection to Treat Biliary and Primary Liver Tumors; and more!

In this issue of Surgical Oncology Clinics, guest editors Drs. Adam Yopp and Maria B. Majella Doyle bring their considerable expertise to the topic of Hepatocellular Carcinoma. Top experts in the field explore promising recent advances in the treatment of all stages of hepatocellular carcinoma (HCC), neoadjuvant or downstaging therapy, the role of LI-RADS in hepatocellular carcinoma, surveillance of hepatocellular carcinoma, liver transplantation, and more. Contains 13 relevant, practice-oriented topics, including the changing epidemiology of HCC within the US and worldwide; HCC surveillance: evidence-based tailored approach; surgical resection outside early stage HCC; minimally invasive techniques for HCC resection; overview of current HCC staging systems: is there an optimal system?; and more. Provides in-depth clinical reviews on hepatocellular carcinoma, offering actionable insights for clinical practice. Presents the latest information on this timely, focused topic under the leadership of experienced editors in the field. Authors synthesize and distill the latest research and practice guidelines to create clinically significant, topic-based reviews.

This issue of Surgical Oncology Clinics of North America, guest edited by Dr. Michael I. D'Angelica, is devoted to Management of Metastatic Liver Tumors. Dr. D'Angelica has assembled expert authors to review the following topics: Surgical management of liver metastases of colorectal cancer; Surgical management of liver metastases of breast cancer; Surgical management of liver metastases of neuroendocrine tumors; Surgical management of liver metastases of sarcoma (including GIST); Surgical management of liver metastases of gynecologic cancers; Surgical management of liver metastases of genitourinary cancers; Surgical management of liver metastases of uveal and dermal melanoma; Is there a role for locoregional therapies for non-colorectal GI malignancies?; Intra-arterial chemotherapy for liver metastases; External beam radiation for liver metastases; Isolated hepatic perfusion for liver metastases; Debate: Improvements in systemic therapies for liver metastases will soon render locoregional treatments obsolete; Debate: Improvements in systemic therapies for liver metastases will increase the role of locoregional treatments; and more!

This issue of Surgical Clinics of North America, guest edited by Dr. Clifford Cho, is devoted to Technical Aspects of Oncological Hepatic Surgery. He has assembled expert authors to review the following topics: Determination of Resectability; Radiographic Characterization of Hepatic Tumors; Chemotherapy-associated Hepatotoxicity; Preoperative Assessment and Optimization of the Future Liver Remnant; Anatomy of Hepatic Resectional Surgery; Resection of Gallbladder Carcinoma; Resection of Hilar Cholangiocarcinoma; Technical Aspects of Orthotopic Liver Transplantation for Hepatocellular Carcinoma; Hemostasis and Hepatic Surgery; Minimally Invasive Hepatic Surgery; Hepatic Tumor Ablation; Hepatic Transarterial Therapies; Hepatic Perfusion Therapy; Hepatic Artery Infusional Chemotherapy; Ex vivo Hepatic Surgery, and more!

In this issue of Surgical Oncology Clinics, guest editors Drs. Adam Yopp and Maria B. Majella Doyle bring their considerable expertise to the topic of Hepatocellular Carcinoma. Top experts in the field explore promising recent advances in the treatment of all stages of hepatocellular carcinoma (HCC), neoadjuvant or downstaging therapy, the role of LI-RADS in hepatocellular carcinoma, surveillance of hepatocellular carcinoma, liver transplantation, and more. Contains 13 relevant, practice-oriented topics, including the changing epidemiology of HCC within the US and worldwide; HCC surveillance: evidence-based tailored approach; surgical resection outside early stage HCC; minimally invasive techniques for HCC resection; overview of current HCC staging systems: is there an optimal system?; and more. Provides in-depth clinical reviews on hepatocellular carcinoma, offering actionable insights for clinical practice. Presents the latest information on this timely, focused topic under the leadership of experienced editors in the field. Authors synthesize and distill the latest research and practice guidelines to create clinically significant, topic-based reviews.