This reference presents detailed discussions of the history, pathology, pathophysiology, and approaches to treatment of the complicated, constantly evolving syndromes known as thrombotic thromocytopenic purpura (TTP), from many different points of view. Hemolytic Uremic syndrome and Thrombotic Thrombocytopenic Purpura offers: extensive analyses of the relationship between HUS and TTP; epidemiological studies of HUS from the UK, Canada, Asia, South Africa and Argentina; investigations of non-renal complications of HUS; perspectives on atypical HUS and post-transplantation HUS; delineations of the association between verotoxin and HUS, HUS and pregnancy, and HUS and cancer and cancer tharapy; information on HUS/TTP in HIV-infected patients; explications of the pathology and pathogenesis of HUS; and approaches to treatment of HUS, prognosis, and long-term follow-up.;In addition, it covers the history and pathogenesis of TTP, von Willebrand factor abnormalities in TTP and HUS, platelet agglutinating proteins in TTP, and the treatment of TTP.;With over 2000 literature citations and figures, this book is for nephrologists, hematologists, oncologists, paediatricians, pathologists, gastroenterologists, internists, endocrinologists, infectious disease specialists, neurologists, gynaecologists, microbiologists, surgeons, geneticsts, epidemiologists, radiologists, and medical school students in these disciplines.

The second edition of a succinct and portable text reviewing the clinical approach to emergency medicine and critical care.

This book reviews current science and applications in fields including thrombosis and hemostasis, signal transduction, and non-thrombotic conditions such as inflammation, allergy and tumor metastasis. It is a detailed, up-to-date, highly referenced text for clinical scientists and physicians, including recent developments in this rapidly expanding field. More than a scientific resource, this is also an authoritative reference and guide to the diagnosis.

The aim of this book is to emphasize firstly that rare and serious conditions can be hidden behind common (mis)leading neurological symptoms. Secondly, it stresses the importance of the collaboration with clinician colleagues - a neuroradiologist needs complete and accurate patient information to make a proper diagnosis or a differential diagnosis that can properly guide further diagnostic processing. The book, structured as an atlas, is divided into three sections according to the most common leading symptoms encountered in hospital emergency units or in outpatient settings. Each proposed case is accompanied by a short medical history, CT and MRI images, and a text describing its most important radiological features. 27 cases were chosen from the authors’ everyday practice: rare and peculiar cases, as well as common cases with a twist. Although both authors are experienced neuroradiologists, several of the cases were surprising and it took considerable time to arrive at the correct diagnosis. A certain level of knowledge and experience, together with information from literature, the Internet or from clinicians, helped them solve most of the cases directly, or after consultation with clinicians and further medical examinations and interventions. This book is mainly intended for residents, general radiologists and neuroradiologists. However, it will also be of help to less experienced colleagues or trainees who need to solve particular cases, encouraging them to think outside the box to find the answers.

An algorithmic approach to interpreting renal pathology, updated in light of recent advances in understanding and new classification schemes.