This book surveys research results on the physical and mathematical modeling, as well as the numerical simulation of complex fluid and structural mechanical processes occurring in the human blood circulation system. Topics treated include continuum mechanical description; choice of suitable liquid and wall models; mathematical analysis of coupled models; numerical methods for flow simulation; parameter identification and model calibration; fluid-solid interaction; mathematical analysis of piping systems; particle transport in channels and pipes; artificial boundary conditions, and many more. The book was developed from lectures presented by the authors at the Oberwolfach Research Institute (MFO), in Oberwolfach-Walke, Germany, November, 2005.

Here's a source of guidance on the analysis of the hemodynamic waveforms generated in the cardiac catheterization lab. It progresses from a review of basic monitoring principles and normal waveforms through an assessment of the waveform data associated with the full range of individual coronary diseases, providing the assistance needed to accurately interpret any findings encountered in practice. Its extremely clinically oriented approach makes it an ideal hands-on tool for any clinician involved in diagnosing cardiac problems using interventional cardiology.

This book offers a mathematical update of the state of the art of the research in the field of mathematical and numerical models of the circulatory system. It is structured into different chapters, written by outstanding experts in the field. Many fundamental issues are considered, such as: the mathematical representation of vascular geometries extracted from medical images, modelling blood rheology and the complex multilayer structure of the vascular tissue, and its possible pathologies, the mechanical and chemical interaction between blood and vascular walls, and the different scales coupling local and systemic dynamics. All of these topics introduce challenging mathematical and numerical problems, demanding for advanced analysis and efficient simulation techniques, and pay constant attention to applications of relevant clinical interest. This book is addressed to graduate students and researchers in the field of bioengineering, applied mathematics and medicine, wishing to engage themselves in the fascinating task of modeling the cardiovascular system or, more broadly, physiological flows.

Biomechanics has a distinguished history extending at least to the 16th Century. However the later half oftbis century has seen an explosion ofthe field with it being viewed as affering exciting challenges for physical scientists and engineers interested in the life sciences, and wonderful opportunities for life scientists eager to collaborate with physical scientists and engineers and to render their scientific work more fundamental. That the field is now weil established and expanding is demonstrated by the formation of a World Committee for Biomechanics and the success and large participation in the 1st and 2nd World Congresses of Biomechanics, held respectively in San Diego in 1990 and in Amsterdam in 1994. With more than 1350 scientific papers delivered at the 2nd World Congress, either within symposia or oral or poster sessions, it would have been out of the question to try to produce comprehensive edited proceedings. Moreover, we are confident that most of the papers have been or will be published in one ofthe excellentjoumals covering the field. But of effort contributed by the plenary lecturers and the tutorial we thought that the large amount and keynote speakers of various symposia deserved tobe recognised in the form of a specific publication, thus also allowing those unable to attend the presentatiops . . tC\ sh?r~ in the findings. Furthermore, we feel that there is now a need to review aspects 'oftlie freld.

Cardiovascular Hemodynamics for the Clinician, 2nd Edition, provides a useful, succinct and understandable guide to the practical application of hemodynamics in clinical medicine for all trainees and clinicians in the field. Concise handbook to help both practicing and prospective clinicians better understand and interpret the hemodynamic data used to make specific diagnoses and monitor ongoing therapy Numerous pressure tracings throughout the book reinforce the text by demonstrating what will be seen in daily practice Topics include coronary artery disease; cardiomyopathies; valvular heart disease; arrhythmias; hemodynamic support devices and pericardial disease New chapters on TAVR, ventricular assist devices, and pulmonic valve disease, expanded coverage of pulmonary hypertension, fractional flow reserve, heart failure with preserved ejection fraction and valvular heart disease Provides a basic overview of circulatory physiology and cardiac function followed by detailed discussion of pathophysiological changes in various disease states

This authoritative book presents the basic knowledge and state-of-the-art techniques necessary to carry out investigations of the cardiovascular system using modeling and simulation. This volume contains chapters on anatomy, physiology, continuum mechanics, as well as pathological changes in the vasculature walls including the heart and their treatments. Methods of numerical simulations are given and illustrated in particular by application to wall diseases.

This book, part of the European Society of Intensive Care Medicine textbook series, teaches readers how to use hemodynamic monitoring, an essential skill for today’s intensivists. It offers a valuable guide for beginners, as well as for experienced intensivists who want to hone their skills, helping both groups detect an inadequacy of perfusion and make the right choices to achieve the main goal of hemodynamic monitoring in the critically ill, i.e., to correctly assess the cardiovascular system and its response to tissue oxygen demands. The book is divided into distinguished sections: from physiology to pathophysiology; clinical assessment and measurements; and clinical practice achievements including techniques, the basic goals in clinical practice as well as the more appropriate hemodynamic therapy to be applied in different conditions. All chapters use a learning-oriented style, with practical examples, key points and take home messages, helping readers quickly absorb the content and, at the same time, apply what they have learned in the clinical setting. The European Society of Intensive Care Medicine has developed the Lessons from the ICU series with the vision of providing focused and state-of-the-art overviews of central topics in Intensive Care and optimal resources for clinicians working in Intensive Care.