On-Line Hemodiafiltration: The Journey and the Vision

On-Line Hemodiafiltration: The Journey and the Vision
Title On-Line Hemodiafiltration: The Journey and the Vision PDF eBook
Author G. Krick
Publisher Karger Medical and Scientific Publishers
Pages 202
Release 2011-12-20
Genre Medical
ISBN 3805599072

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On-line HDF represents a major technical development in the delivery of hemodialysis therapy: It combines the properties of increased diffusion available in current high-flux membranes with convective removal of between 6 and 30 liters per treatment and requires the use of ultrapure water and online filtration of replacement fluid. On-line HDF has been successfully introduced in Europe and Asia and is routinely prescribed for dialysis patients in these regions.The book at hand summarizes the history and achievements of on-line HDF in four parts: A report of the technological development in both machine and fiber/dialyzer is followed by a description of the challenges encountered in the evolution of on-line HDF, collecting the accounts of clinical key opinion leaders who had been involved in its early application. The third part presents a comprehensive review of the clinical results achieved with on-line HDF from its inception to the present times, in which it represents the clinical golden standard. The fourth and final part is dedicated to on-line HDF as a ‘vision’ for the future.

Continuous Renal Replacement Therapy

Continuous Renal Replacement Therapy
Title Continuous Renal Replacement Therapy PDF eBook
Author John A. Kellum
Publisher Oxford University Press
Pages 329
Release 2016
Genre Medical
ISBN 019022553X

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Continuous Renal Replacement Therapy provides concise, evidence-based, bedside guidance for the management of critically ill patients with acute renal failure, offering quick reference answers to clinicians' questions about treatments and situations encountered in daily practice.

Hemodiafiltration

Hemodiafiltration
Title Hemodiafiltration PDF eBook
Author Claudio Ronco
Publisher Karger Medical and Scientific Publishers
Pages 249
Release 2007-01-01
Genre Medical
ISBN 3805582889

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A concise handbook on clinical and technical possibilities The application of hemodiafiltration has been restricted until recently, when a broader clinical application has been made possible due to evidence from large studies and clinical investigations. This book provides an updated review of the evolution, advances and recent results achieved by hemodiafiltration in the clinical arena. The first part is devoted to historical notes and an outline of the evolution of different forms of hemodiafiltration, made possible by technological developments in the fields of membranes, machines and fluids. The next section describes the theoretical rationale for hemodiafiltration, providing a detailed analysis of the involved mass separation processes, the hydraulic properties of the dialyzers, fluid mechanics and crossfiltration in hollow fiber hemodialyzers. An outline of different hemodiafiltration techniques, also reporting peculiar transport mechanisms and related technology, is given next, and a section on the clinical effects of hemodiafiltration concludes this book. Including different technologies, the publication offers a complete overview of the technical and clinical possibilities provided by hemodiafiltration in its widest concept, ranging from the molecular basis to the most practical application. It will be a valuable tool for the implementation of hemodiafiltration in daily practice aimed at beginners and experts, scientists and physicians, students and senior faculty members alike.

Hemodiafiltration

Hemodiafiltration
Title Hemodiafiltration PDF eBook
Author Hideki Kawanishi
Publisher Karger Medical and Scientific Publishers
Pages 228
Release 2011
Genre Medical
ISBN 3805595603

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Hemodiafiltration (HDF) for the treatment of end-stage renal disease patients is predominantly performed in European countries and in Japan, with some differences in technique such as rate of blood flow and dialysis fluid delivery systems. The main focus of this book is on the clinical importance of online HDF, the techniques of which have been re-evaluated with the introduction of super high-flux membrane dialyzers. After a brief introduction into the history of HDF, recent advances and clinical experiences of HDF are summarized, including water quality control for dialysis fluid, equipped system for safe use, clinical advantages, and theoretical aspects of HDF. Moreover, at the end of each chapter researchers and scientists discuss problems into which further research is needed. Clinicians and scientists involved in the treatment of end-stage renal disease patients will find this publication an essential source of information. Moreover, it may also serve as a textbook for those who are planning to start HDF in their clinics or who are studying blood purification therapies in medical schools, nursing schools and even in engineering schools related to medical technologies.

Hemodiafiltration

Hemodiafiltration
Title Hemodiafiltration PDF eBook
Author Menso J. Nubé
Publisher Springer
Pages 346
Release 2015-11-10
Genre Medical
ISBN 3319233327

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This book gives a complete description of online hemodiafiltration, in five sections. It is unique in the systematic and complete way in which hemodiafiltration is described. Each chapter is completed by a point-to-point summary of essential information, in a separate text box. Part of the book is dedicated to the theoretical background of convective clearance. In this part, safety issues and quality control is reviewed (especially on the quality of water for dialysis and substitution fluid), as well as equipment (both dialyzers and machines) with which this treatment can be performed. As recently the results of several randomized controlled trials were available, the effect of hemodiafiltration on hard clinical end points (mortality and morbidity) is discussed in detail. This has not been done before, as the most recent book/journal on hemodiafiltration was published in 2011, before the results of the 3 randomized controlled trials were published. Furthermore, the methodological quality of the trials is discussed by an expert, in order to help the readers in their judgment of the trials Part of the book concentrates on the effect of the treatment on several biomarkers and uremic toxins. Several clinically relevant issues is discussed separately, such as the prescription of anticoagulation during the treatment, drug prescription and clearance for patients treated with hemodiafiltration, and hemodynamic stability. Finally, a practical guide on how to perform the treatment is provided. In this unique section, seemingly simple but important details of hemodiafiltration-treatment is discussed, such as the importance of needle size for blood flow rates, the difference between filtration fraction and substitution ratio, the different targets that can be set and how to reach them. As most literature is mainly focused on theoretical issues, this unique feature really will help the field to perform hemodiafiltration, and answer practical questions.

Expanded Hemodialysis

Expanded Hemodialysis
Title Expanded Hemodialysis PDF eBook
Author C. Ronco
Publisher Karger Medical and Scientific Publishers
Pages 216
Release 2017-09-14
Genre Medical
ISBN 3318061174

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Despite constant significant advances, cardiovascular as well as more general outcomes of hemodialysis treatment remain unsatisfactory. The introduction of innovative 'high retention onset' membranes has led to the development of a new treatment modality called 'expanded hemodialysis' (HDx), which is the focus of this book. This new therapy is likely to benefit end-stage kidney disease patients, thanks to enhanced removal of molecules retained by current dialysis techniques. HDx is simple to set up and application does not require special hardware or specific nursing skills. This book contains emerging evidence and fascinating new hypotheses on HDx. It is highly recommended for all physicians and healthcare professionals who are caring for dialysis patients and are seeking innovation and improved care solutions. It will also be of considerable interest to students and fellows.

Handbook of Dialysis

Handbook of Dialysis
Title Handbook of Dialysis PDF eBook
Author John T. Daugirdas
Publisher Lippincott Williams & Wilkins
Pages 806
Release 2012-02-20
Genre Medical
ISBN 1451165919

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The revised, updated Fourth Edition of this popular handbook provides practical, accessible information on all aspects of dialysis, with emphasis on day-to-day management of patients. Chapters provide complete coverage of hemodialysis, peritoneal dialysis, special problems in dialysis patients, and problems pertaining to various organ systems. This edition reflects the latest guidelines of the National Kidney Foundation's Kidney Disease Outcomes Quality Initiative (KDOQI) on hemodialysis and peritoneal dialysis adequacy and on nutrition. New chapters cover chronic kidney disease management in predialysis patients, frequent daily or nocturnal hemodialysis, and hemodiafiltration. Chapters on venous and arteriovenous access have been completely revised. Each chapter provides references to relevant Web sites.