This book describes a comprehensive framework for hardware/software co-design, optimization, and use of robust, low-cost, and cyberphysical digital microfluidic systems. Readers with a background in electronic design automation will find this book to be a valuable reference for leveraging conventional VLSI CAD techniques for emerging technologies, e.g., biochips or bioMEMS. Readers from the circuit/system design community will benefit from methods presented to extend design and testing techniques from microelectronics to mixed-technology microsystems. For readers from the microfluidics domain, this book presents a new design and development strategy for cyberphysical microfluidics-based biochips suitable for large-scale bioassay applications. • Takes a transformative, “cyberphysical” approach towards achieving closed-loop and sensor feedback-driven biochip operation under program control; • Presents a “physically-aware” system reconfiguration technique that uses sensor data at intermediate checkpoints to dynamically reconfigure biochips; • Enables readers to simplify the structure of biochips, while facilitating the “general-purpose” use of digital microfluidic biochips for a wider range of applications.

This book provides a single-source reference to the state-of-the-art in logic synthesis. Readers will benefit from the authors’ expert perspectives on new technologies and logic synthesis, new data structures, big data and logic synthesis, and convergent logic synthesis. The authors describe techniques that will enable readers to take advantage of recent advances in big data techniques and frameworks in order to have better logic synthesis algorithms.

This book provides an insightful guide to the design, testing and optimization of micro-electrode-dot-array (MEDA) digital microfluidic biochips. The authors focus on the characteristics specific for MEDA biochips, e.g., real-time sensing and advanced microfluidic operations like lamination mixing and droplet shape morphing. Readers will be enabled to enhance the automated design and use of MEDA and to develop a set of solutions to facilitate the full exploitation of design complexities that are possible with standard CMOS fabrication techniques. The book provides the first set of design automation and test techniques for MEDA biochips. The methods described in this book have been validated using fabricated MEDA biochips in the laboratory. Readers will benefit from an in-depth look at the MEDA platform and how to combine microfluidics with software, e.g., applying biomolecular protocols to software-controlled and cyberphysical microfluidic biochips.

This book provides a comprehensive overview of flow-based, microfluidic VLSI. The authors describe and solve in a comprehensive and holistic manner practical challenges such as control synthesis, wash optimization, design for testability, and diagnosis of modern flow-based microfluidic biochips. They introduce practical solutions, based on rigorous optimization and formal models. The technical contributions presented in this book will not only shorten the product development cycle, but also accelerate the adoption and further development of modern flow-based microfluidic biochips, by facilitating the full exploitation of design complexities that are possible with current fabrication techniques.

This book constitutes the refereed proceedings of the 21st International Symposium on VLSI Design and Test, VDAT 2017, held in Roorkee, India, in June/July 2017. The 48 full papers presented together with 27 short papers were carefully reviewed and selected from 246 submissions. The papers were organized in topical sections named: digital design; analog/mixed signal; VLSI testing; devices and technology; VLSI architectures; emerging technologies and memory; system design; low power design and test; RF circuits; architecture and CAD; and design verification.

This book features a collection of high-quality research papers presented at the 10th International Symposium on Applied Computing for Software and Smart systems (ACSS 2023), to be held during September 15–16, 2023, in Kolkata, India. The book presents innovative works by undergraduate, graduate students as well as Ph.D. scholars. The emphasis of the workshop is on software and smart systems and research outcomes on other relevant areas pertaining to advancement of computing.

Embedded system designers are constantly looking for new tools and techniques to help satisfy the exploding demand for consumer information appliances and specialized industrial products. One critical barrier to the timely release of embedded system products is integrating the design of the hardware and software systems. Hardware/software co-design is a set of methodologies and techniques specifically created to support the concurrent design of both systems, effectively reducing multiple iterations and major redesigns. In addition to its critical role in the development of embedded systems, many experts believe that co-design will be a key design methodology for Systems-on-a-Chip. Readings in Hardware/Software Co-Design presents the papers that have shaped the hardware/software co-design field since its inception in the early 90s. Field experts -- Giovanni De Micheli, Rolf Ernst, and Wayne Wolf -- introduce sections of the book, and provide context for the paper that follow. This collection provides professionals, researchers and graduate students with a single reference source for this critical aspect of computing design. * Over 50 peer-reviewed papers written from leading researchers and designers in the field * Selected, edited, and introduced by three of the fields' most eminent researchers and educators * Accompanied by an annually updated companion Web site with links and references to recently published papers, providing a forum for the editors to comment on how recent work continues or breaks with previous work in the field