This handbook is the next volume in the series of the scientific and educational publications of the European Society of Preventive, Regenerative and Anti-Aging Medicine. To promote the development of the science and practice of anti-ageing and active longevity, ESAAM has published in 2023 the Handbook of Anti-Aging Medicine. This cornerstone book was devoted to main theoretical issues in combating the mechanisms of aging. Current handbook provides the basics of practical life extension protocols. Leading specialists in regenerative and longevity medicine presented their valuable recommendations. Special attention is paid to the fundamental principles of the longevity clinic, as well as practical instructions on which of the existing protocols are the most effective from the point of view of international experts. Their experience is described in 13 chapters and covers the next fields of the longevity medicine: • Immune ageing • Hormetic nutrients • Measurements of aging • Policies for healthy longevity • The fundamentals of Mayr medicine in longevity • How sexuality and eroticism promote healthy ageing • Protocols of regeneration technologies for the longevity medicine • Holistic approaches to healthy longevity • International collaboration in longevity • Cell and molecular therapies This book is highly recommended for all physicians working with ageing patients and persons having disorders promoting premature and accelerated ageing. Also, practical focus makes this book essential for managers and specialists of the preventive, anti-aging and longevity medicine.

Manual of Healthy Longevity and Wellbeing is your easy-to-follow, practical guide to maximising your chance of living a long, happy life in good health. Skilled physician and world expert on longevity, Professor Luigi Fontana, has drawn upon the latest science to give you three keys to longevity: recipes for a healthy diet rich in flavour, a simple exercise plan and a wellbeing guide. With strategies to aid your progress, this complete program draws on evidence-based principles of eliminating empty calories and enhancing nutritional value; an exercise that is simple and achievable; and tools to improve your emotional wellbeing. Many of the most common chronic illnesses in our society are avoidable and Professor Fontana’s plan shows us all how to boost our metabolic and immune health. Offering more than 80 tasty Mediterranean-style recipes with vibrant photography, a step-by-step exercise plan that includes, aerobic, weight-bearing and stretch exercises, along with guidance on overcoming stress, getting quality sleep and simple meditation techniques. With more than 20 years of research and clinical practice, this plan will show you just how simple it is to transform your lifestyle and achieve total health not just for now but for the rest of your life. Professor Luigi Fontana, M.D., Ph.D. is a highly skilled physician scientist who is recognised as the leading world expert on longevity. Credited with conducting the foundational research that gave rise to the 5:2 diet, Professor Fontana’s revolutionary work is leading the world on longevity and the factors involved in living a long and healthy life.

"A fun, illustrated book of simple rules everyone should follow in order to live a long, healthy life, derived from Dr. Agus's #1 New York Times bestselling book, The End of Illness"--

This book was created to be a user manual because it's not just technology that needs a guide; the human-machine also requires its instruction manual. By addressing a few conditions, one is able to prevent, cure, or at least improve most diseases. The question is: how to raise awareness among those who do not think about targeting the cause, but only the symptom? Creating guidelines for maintaining health and not just follow industry protocols for treating illnesses is the main goal of The Longevity Handbook. This book summarizes decades of research and offers new studies and findings to be applied for integral health: a new awareness about the functioning of the human-machine and how to get the most out of it, supply it with the best, achieve high performance, eliminate what hinders its operation, adjust all gears, and strengthen its system. With adjustments and prevention, this wonderful and perfect machine will have more longevity and, above all, quality of life while it is in operation. Unique formulas developed by the author based on vitamins, minerals, fibers, and probiotics available in foods and supplements are also presented in this book, along with their associated benefits, implications for immunity, and overall health. The purpose of this work is to serve as a source of information and research showing another view on the origin of diseases, which are often omitted or neglected in orthodox prevention and treatment. Examples are given on the benefits that can be achieved by stopping to use a single, common tool (drugs) and starting to treat the causes, using various sciences such as clinical nutrition, medical biochemistry, orthomolecular practice, phytotherapy, biophysics, homeopathy, homotoxicology, and traditional Chinese medicine.

Handbook of the Biology of Aging, Eighth Edition, provides readers with an update on the rapid progress in the research of aging. It is a comprehensive synthesis and review of the latest and most important advances and themes in modern biogerontology, and focuses on the trend of ‘big data’ approaches in the biological sciences, presenting new strategies to analyze, interpret, and understand the enormous amounts of information being generated through DNA sequencing, transcriptomic, proteomic, and the metabolomics methodologies applied to aging related problems. The book includes discussions on longevity pathways and interventions that modulate aging, innovative new tools that facilitate systems-level approaches to aging research, the mTOR pathway and its importance in age-related phenotypes, new strategies to pharmacologically modulate the mTOR pathway to delay aging, the importance of sirtuins and the hypoxic response in aging, and how various pathways interact within the context of aging as a complex genetic trait, amongst others. Covers the key areas in biological gerontology research in one volume, with an 80% update from the previous edition Edited by Matt Kaeberlein and George Martin, highly respected voices and researchers within the biology of aging discipline Assists basic researchers in keeping abreast of research and clinical findings outside their subdiscipline Presents information that will help medical, behavioral, and social gerontologists in understanding what basic scientists and clinicians are discovering New chapters on genetics, evolutionary biology, bone aging, and epigenetic control Provides a close examination of the diverse research being conducted today in the study of the biology of aging, detailing recent breakthroughs and potential new directions

This handbook focuses on different aspects of anti-aging and both preventive and regenerative medicine. It includes analysis of the paradigm of ageing and concepts of anti-aging medicine. Standards and technologies are highlighted in over twenty chapters all authored by international experts in regenerative medicine. Topics covered include: • Ageing, aging, and anti-aging: A Decalogue for anti-aging medicine • Lessons from Sicilian centenarians for anti-aging medicine • Molecular biomarkers and genetic aspects of aging • Future of peptides in clinical practice • Mitochondrial approaches in anti-aging medicine and in SARS-CoV2 infection • Tissue-specific autoantibodies in preventive medicine • Chronic stress as a psycho-neuro-immunological dysfunction • Gut-associated immune system and its health implications • Regenerative medicine with platelet-rich-plasma • Alzheimer’s disease: Preventive and anti-aging neurology • Autistic spectrum disorder and mitochondrial medicine • Integrative hormonal approach in anti-aging medicine • Preventive cardiology and phlebology • Aesthetic and anti-aging medicine • Preventive ophthalmology • Preventive oncology • Nutrition in healthy aging • Physical activity and fitness paradigms for anti-aging and longevity Recommended reading for clinicians working in anti-aging medicine as well as ageing people. The authors hope it will set a new “standard of anti-aging medicine” and as a tool in planning for the inevitable challenges we all will face caring for ageing patients and creating preventive-health programs.