Handbook of Solubility Data for Pharmaceuticals
Title | Handbook of Solubility Data for Pharmaceuticals PDF eBook |
Author | Abolghasem Jouyban |
Publisher | CRC Press |
Pages | 554 |
Release | 2009-08-26 |
Genre | Medical |
ISBN | 1439804885 |
Aqueous solubility is one of the major challenges in the early stages of drug discovery. One of the most common and effective methods for enhancing solubility is the addition of an organic solvent to the aqueous solution. Along with an introduction to cosolvency models, the Handbook of Solubility Data for Pharmaceuticals provides an extensive datab
Handbook of Aqueous Solubility Data
Title | Handbook of Aqueous Solubility Data PDF eBook |
Author | Samuel H. Yalkowsky |
Publisher | CRC Press |
Pages | 1513 |
Release | 2003-03-26 |
Genre | Medical |
ISBN | 0203490398 |
Over the years researchers have reported solubility data in the chemical, pharmaceutical, engineering, and environmental literature for several thousand organic compounds. Until now, this information has been scattered throughout the literature. Containing over 16,000 solubility data points for more than 4,000 organic compounds, Handbook of Aqueous
Handbook of Aqueous Solubility Data
Title | Handbook of Aqueous Solubility Data PDF eBook |
Author | Samuel H. Yalkowsky |
Publisher | CRC Press |
Pages | 1622 |
Release | 2016-04-19 |
Genre | Medical |
ISBN | 1439802467 |
Over the years, researchers have reported solubility data in the chemical, pharmaceutical, engineering, and environmental literature for several thousand organic compounds. Until the first publication of the Handbook of Aqueous Solubility Data, this information had been scattered throughout numerous sources. Now newly revised, the second edition of
Handbook of Aqueous Solubility Data
Title | Handbook of Aqueous Solubility Data PDF eBook |
Author | Samuel H. Yalkowsky |
Publisher | CRC Press |
Pages | 1512 |
Release | 2003-03-26 |
Genre | Science |
ISBN | 9780849315329 |
Over the years researchers have reported solubility data in the chemical, pharmaceutical, engineering, and environmental literature for several thousand organic compounds. Until now, this information has been scattered throughout the literature. Containing over 16,000 solubility data points for more than 4,000 organic compounds, Handbook of Aqueous Solubility Data provides an extensive compilation of published aqueous solubility data for a wide variety of organic nonelectrolytes and unionized weak electrolytes. It includes data for pharmaceuticals, pollutants, nutrients, herbicides, pesticides, agricultural, industrial, and energy related compounds. Each compound is identified by a sequential number along with molecular formula, compound name, synonyms, molecular weight, CAS Registry Number, melting point, and boiling point if available. Each entry has a five-point evaluation score for the quality of the reporting of the data, along with the full citation, and comments from the authors when necessary. The user-friendly format gives a clear depiction of each piece of solubility data with enough information to estimate its validity. Handbook of Aqueous Solubility Data gives you a portable, accessible resource for solubility data of numerous compounds and a single system for the evaluation of the data supplied.
Predicting Solubility of New Drugs
Title | Predicting Solubility of New Drugs PDF eBook |
Author | Alex Avdeef |
Publisher | |
Pages | 0 |
Release | 2024 |
Genre | Drug development |
ISBN | 9781032625249 |
"In pharmaceutical research, solubility plays a key part in the assessment of pharmacokinetic risks. Poor drug absorption, reduced efficacy, excessive metabolism and adverse reactions are frequently related to issues of drug solubility. During early discovery research at pharmaceutical companies, many thousands of molecules are considered. Most are rejected due to perceived unfavorable properties. Here the author uses the so-called Wiki-pS0TM database which forms the backbone of this unique handbook. Also discussed is the emerging class of therapeutically-promising research molecules called PROTACs (proteolysis-targeting chimeras), showing a propensity for 'undruggable' targets"--
Hansen Solubility Parameters
Title | Hansen Solubility Parameters PDF eBook |
Author | Charles M. Hansen |
Publisher | CRC Press |
Pages | 546 |
Release | 2007-06-15 |
Genre | Science |
ISBN | 1420006835 |
Hansen solubility parameters (HSPs) are used to predict molecular affinities, solubility, and solubility-related phenomena. Revised and updated throughout, Hansen Solubility Parameters: A User's Handbook, Second Edition features the three Hansen solubility parameters for over 1200 chemicals and correlations for over 400 materials including p
Handbook of Dissolution Testing
Title | Handbook of Dissolution Testing PDF eBook |
Author | William A. Hanson |
Publisher | |
Pages | 159 |
Release | 1991 |
Genre | Medical |
ISBN | 9780943330228 |
Dissolution testing is used in the pharmaceutical industry to determine a drug's bioavailability and the bioequivalence of two drugs. Hanson details the techniques used, and provides guidelines for starting and operating a program. First published "nearly ten years ago." Available from Aster Publishing Corporation, 859 Willamette Street, Eugene OR 97440. Annotation copyrighted by Book News, Inc., Portland, OR