The nutritional and medicinal value of metals, such as zinc, calcium, and iron, has been known in traditional medicine for a long time. Other metals, such as silver and gold, may also have therapeutic and health benefits. Ancient medicines have long incorporated their use in the treatment of diseases, and they have also more recently been explored for treatment in allopathic medicine, birthing the concept of metallonutraceuticals. The challenge of using metals in the human body is to find forms that are safe and effective. Handbook of Metallonutraceuticals presents basic concepts related to the nutritional and therapeutic use of metals, product development strategies, and some ideas ready to be applied for condition-specific metallonutraceuticals. The book begins with an overview of the nutraceuticals field and the need for metallonutraceuticals. It considers the roles of various metals in metabolism, reviews the ethnopharmacology and ethnomedicine of metals, and covers the characterization and possible properties of metallonutraceuticals. It also examines bioavailability and drug interactions, and therapeutic applications of nanometals including use as imaging agents, in cancer diagnosis and treatment, as antibacterials and antivirals, in ocular disease, and in neurodegenerative diseases. The book explores the use of metals in traditional Chinese medicine, potential applications for metalloenzymes, the use of nanosilver in nutraceuticals, and the potential of gold nanoparticles as a drug delivery system. In addition, it addresses intellectual property rights and regulatory considerations regarding metallonutraceuticals. Using an interdisciplinary approach, this user-friendly text provides a knowledge base and inspiration for new research in this exciting field.

Shows how nanotechnology can be used to develop better functional foods and nutraceuticals. Provides detailed knowledge of current development in nutraceuticals. Discusses marketing and consumer acceptance of nanomaterials. Reviews current governmental regulations.

This book addresses various clinical and sub clinical applications of antioxidant nutraceuticals, with a primary focus on preventive use for general wellness, common ailments, and such chronic illnesses as cancer and neurological applications. This unique book captures the applications of natural antioxidants, which have been used for thousands of years in Traditional Chinese Medicine and Ayurvedic Medicine as well as modern nutraceuticals formulations. It covers antioxidant applications in clinical scenarios including the historical perspective, basic antioxidant properties and applications, anti-inflammatory properties, and antioxidant applications in a variety of clinical conditions.

Recent major shifts in global health care management policy have been instrumental in renewing interest in herbal medicine. However, literature on the development of products from herbs is often scattered and narrow in scope. Herbal Bioactives and Food Fortification: Extraction and Formulation provides information on all aspects of the extraction o

A reference is needed that addresses the recent progress in aspects of PK/PD methods and developments of nanoparticles for novel drug delivery systems. No other consolidated published reference discusses the PK/PD study of nanoparticle drug delivery systems. This book discusses the advantages of nanoparticle drug delivery systems (NPDDS) in enhancing the pharmacokinetics of many drugs that are not easily metabolized or that obtain the desired therapeutic effect with minimum toxicity. The authors provide an overview of biodistribution with a focus on polymer and lipid nanoparticles. This thorough reference is divided into three parts: Modelling, Specific carries and their potential to treat specific diseases.

Focused more specifically on the recent advances in applications of various metals and their complexes used in biomedicine, particularly in the diagnosis and treatment of chronic diseases. The editors give equal importance to other key aspects such as toxicological issues and safety concerns. The application of metals in the biomedical field is highly interdisciplinary and has a broad appeal across all biomedical specialties. Biomedical Applications of Metals is particularly focused on covering the role of metals in medicine and the development of novel therapeutic products and solutions in the form of alternative medicines, and some topics on Indian traditional medicine i.e., “Ayurveda”. In Section I, the book discusses the role of metals in medicines and include chapters on nanoparticles, noble metals, medical devices, copper. selenium, silver, and microbial pathogens; while Section II includes topics on metals toxicity including heavy metals, carcinogens, cancer therapy, Bhasma’s and chelating agents used in Ayurveda, and biochemical and molecular targets including actions of metals. These new and emerging concepts of applications of metals in medicine, their crucial role in management of microbial resistance, and their use in the treatment of various chronic diseases is essential information for toxicologists, and clinical and biomedical researchers.

Genomics and related areas of research have contributed greatly to the understanding of the cellular and molecular mechanisms underlying diet–disease relationships. In the past decade, the evidence has become stronger for a direct link between genome/epigenome damage and increased risk for adverse health outcomes. It is now exceedingly clear that micronutrients are critical as cofactors for many cellular functions, including DNA repair enzymes, methylation of CpG sequences, DNA oxidation, and/or uracil incorporation into DNA. Nutrigenomics and Nutraceuticals: Clinical Relevance and Disease Prevention brings new perspectives on disease prevention strategy based on the genomic knowledge and nutraceuticals of an individual and the diet he or she receives. This book discusses the integration and application of genetic and genomics technology into nutrition research and paves the way for the development of nutrition research programs that are aimed at the prevention and control of chronic disease through genomics-based nutritional interventions. In this book, the editors bring together a wide spectrum of nutritional scientists worldwide to contribute to the growing knowledge in the field of nutrigenomics and nutraceuticals.