Oncology has developed as a subspecialty of medicine with unique and often complex clinical problems. This handbook ofhematologic and oncologic emer gencies provides a compact, concise, yet comprehensive guide to the manage ment of a variety of difficult clinical situations. The authors of the various chapters are all clinicians with experience in the management of these difficult patients. Their efforts provide insight and a ready source of practical infor mation which lends itself to use in the clinic and in the inpatient ward. The authors sincerely hope that this handbook will be of service to house officers and fellows alike, as they develop skills in the management of the emergent problems of patients with hematologic and other neoplasms. Janice P. Dutcher Peter H. Wiernik Bronx, New York, ;; Contents 1. Syndrome of Inappropriate Antidiuretic Hormone Secretion and Hyponatremia ... 000 ... Stuart L. Marcus, M.D., Ph. D., and Joachim Z. Fuks, M.D. 1. Introduction ... 1 2. Mechanisms ... 3 3. Etiology ... . 3 4. Diagnosis ... 5 5. Treatment ... . 6 References ... . 8 2. Acute Tumor Lysis Syndrome: Prevention and Management . . 9 Stuart L. Marcus, M.D., Ph. D., and Avi I. Einz;ig, M.D. 1. Introduction ... 9 2. Risk Factors for the Development of Azotemia in Acute Tumor Lysis Syndrome ... 10 3. Metabolic Abnormalities That Occur during Acute Tumor Lysis Syndrome ... 11 ... 4. Prevention of Acute Tumor Lysis Syndrome: Management prior to Beginning Chemotherapy ... 13 ... 5. Posttreatment Management: Indications for Dialysis ... 14 . . References ... 15 ...

This issue of Emergency Medicine Clinics focuses on Hematology and Oncology Emergencies, with topics including: Cardiovascular toxicities of cancer therapies; The latest cancer agents and their complications; Infections in the cancer patient; Pediatric oncologic emergencies; Rapid fire oncologic emergencies; Rapid fire hypercalcemia; Rapid fire sickle cell disease; Rapid fire SVC Syndrome; The Cancer ED; EM Oncology Fellowship; Anticoagulation Reversal; and Rapid Fire Blast Crisis/Hyperviscosity.

This issue of Hematology/Oncology Clinics, edited by Drs. John Perkins and and Jonathan Davis, focuses on emergencies related to Hematology/Oncology and covers topics such as: Oncologic Mechanical Emergencies, Neutropenic Fever, Oncologic Metabolic Emergencies, Acute Leukemias, Pediatric Oncologic Emergencies, Chemotherapeutic Medications and their Emergent Complications, Anemia, Thrombotic Microangiopathies (TTP, HUS, HELLP), Congenital Bleeding Disorders, Acquired Bleeding Disorders and Antithrombotic agents, Sickle Cell Disease, and more!

MDS/MPN With Ring Sideroblasts and Thrombocytosis

The revised guide to the diagnosis, management, and treatment of blood disorders and cancer in children Children with blood disorders and cancer are a unique population that require specialized diagnostic considerations and management. The Handbook of Pediatric Hematology and Oncology has been designed to provide clinicians of all levels with practical guidance through an up-to-date algorithmic approach to these conditions. Assembled by a team of experts from the world-class Children's Hospital & Research Center Oakland, this updated third edition: Presents up-to-date management and treatment guidelines for the most common pediatric blood disorders and malignancies Provides an updated algorithmic approach for the diagnosis and management of the most common conditions and suggested readings Utilizes rapid-referral tables containing visual representations of symptoms, lab findings, differentials, and treatment guidance Incorporates case studies covering different hematologic and oncologic conditions, such as hemolytic anemia, sickle cell disease, hemophilia, neuroblastoma, and sarcomas of the soft tissue and bone Includes a useful formulary that lists chemotherapy agents, dosing, mechanism of action, pregnancy category, indications, and side effects Covers transfusion medicine, stem cell transplantation, management of central venous catheters, acute pain management, oncologic emergencies, and chemotherapy basics With its direct guidance and portable design, the Handbook of Pediatric Hematology and Oncology: Children's Hospital & Research Center Oakland, Third Edition, will prove an invaluable resource to medical students, trainees and residents, pediatric hematology and oncology nurses, pediatricians, and early-career providers in pediatric hematology/oncology.

This new resource on managing oncologic emergencies is directed at all health care professionals who care for patients with cancer or survivors. Edited and written by clinician-experts at The University of Texas MD Anderson Cancer Center, the book covers the full range of oncologic emergencies, from cardiac and neurologic to orthopedic to hematologic, and addresses important palliative care, ethical, and Emergency Department considerations. Chapters are structured with busy clinicians in emergent and urgent settings in mind, and each chapter concludes with a series of key practice points and a list of suggested readings for those who wish to delve deeper into a subject. For any clinician facing the increasing number of patients who experience an oncologic emergency, this is an up-to-date, clinically focused, and authoritative resource.