The chemical industry is increasingly faced with problems arizing from chemicals produced during the manufacture of halogenated biphenyls or phenols. Knowledge of these chemicals and their destructive properties is sporadic, and the acute toxicity of this group varies widely. This informative revised edition presents the chemistry, environmental pollution problems, animal toxicology and information about structure-activity relationships. A brief overview is given of worker exposure and occupational illness. The book is divided into three parts: chemistry and environmental contamination; experimental toxicology; and human exposure and effects. Because of the great deal of interest in these compounds much new research work has been conducted since the first edition of this book was published. This revised edition has retained the effectiveness and clarity of the first edition, while being supplemented with new information, condensed old information, and examples of recent incidents.

1. PRODUCTION, PROPERTIES AND USAGE. 2. CHEMICAL PROPERTIES AND ANALYTICAL METHODS. 3. ENVIRONMENTAL POLLUTION OF AIR, WATER AND SOIL. 4. METABOLISM, UPTAKE, STORAGE AND BIOACCUMULATION. 5. ACUTE AND CHRONIC TOXICITY, CARCINOGENESIS, REPRODUCTION, TERATOGENESIS AND MUTAGENESIS IN ANIMALS. 6. STRUCTURE ACTIVITY RELATIONSHIPS FOR THE BIOCHEMICAL EFFECTS AND THE RELATIONSHIP TO TOXICITY. 7. CHEMICAL PORPHYRIA. 8. IMMUNE ALTERATIONS. 9. HUMAN EXPOSURE. 9A. GENERAL POPULATION EXPOSURE TO ENVIRONMENTAL CONCENTRATIONS OF HALOGENATED BIPHENYLS. 9B1. YUSHO. 9B2. LOCALIZED CONTAMINATION WITH TCDD-SEVESO, MISSOURI AND OTHER AREAS. 9C. OCCUPATIONAL EXPOSURE.

This updated and expanded Second Edition of Dr. Erickson's Analytical Chemistry of PCBs appears a decade after the first and is completely revised and updated. The changes from the First Edition reflect the significant growth in the area and a growing appreciation of the importance of PCB analysis to our culture. This book is a comprehensive review of the analytical chemistry of PCBs. It is part history, part annotated bibliography, part comparison, and part guidance. Featuring a new chapter on analyst/customer interactions and several new appendices, the Second Edition is an invaluable resource for both chemists with no experience in PCB analysis and seasoned PCB researchers. All topics have been more thoroughly treated and updated in this new edition to reflect advances made in the last decade, especially:

It is becoming increasingly realised that the oceans and rivers, in particular, are not unlimited reservoir into which waste can be dumped and that control of these emissions is necessary if complete destruction of the environment is to be avoided. T. R. Crompton has drawn together up-to-date information on these issues and on the relevant analytical methods needed by all experts active in environmental protection and toxicology.