Recent studies have indicated that epigenetic processes may play a major role in both cellular and organismal aging. These epigenetic processes include not only DNA methylation and histone modifications, but also extend to many other epigenetic mediators such as the polycomb group proteins, chromosomal position effects, and noncoding RNA. The topics of this book range from fundamental changes in DNA methylation in aging to the most recent research on intervention into epigenetic modifications to modulate the aging process. The major topics of epigenetics and aging covered in this book are: 1) DNA methylation and histone modifications in aging; 2) Other epigenetic processes and aging; 3) Impact of epigenetics on aging; 4) Epigenetics of age-related diseases; 5) Epigenetic interventions and aging: and 6) Future directions in epigenetic aging research. The most studied of epigenetic processes, DNA methylation, has been associated with cellular aging and aging of organisms for many years. It is now apparent that both global and gene-specific alterations occur not only in DNA methylation during aging, but also in several histone alterations. Many epigenetic alterations can have an impact on aging processes such as stem cell aging, control of telomerase, modifications of telomeres, and epigenetic drift can impact the aging process as evident in the recent studies of aging monozygotic twins. Numerous age-related diseases are affected by epigenetic mechanisms. For example, recent studies have shown that DNA methylation is altered in Alzheimer’s disease and autoimmunity. Other prevalent diseases that have been associated with age-related epigenetic changes include cancer and diabetes. Paternal age and epigenetic changes appear to have an effect on schizophrenia and epigenetic silencing has been associated with several of the progeroid syndromes of premature aging. Moreover, the impact of dietary or drug intervention into epigenetic processes as they affect normal aging or age-related diseases is becoming increasingly feasible.

In Grow Younger, Live Longer, Deepak Chopra, a pioneer in mind/body medicine, applies his decades of research and knowledge to actually reverse the aging process. This simple and practical step-by-step program designed by Dr. Chopra and his associate, David Simon, M.D., shows how it is essential to renew all dimensions of the self—the body, mind, and spirit—in order to feel and look younger. The ten-step program detailed in this book will immediately improve your sense of well-being, and the three Daily Actions accompanying each step will help you thoroughly integrate the age reversal process into your life. Learn how to maintain a youthful mind, cultivate flexibility, strengthen your immune system, nourish your body, and much more. As you begin to reverse your biological age, you will find yourself tapping into your inner reservoirs of unlimited energy, creativity, and vitality.

What if you could look years younger without a facelift, without skin resurfacing, without a laser peel, without any temporary fixes meant to fool the eye? What if you could simply grow young? With Zia Wesley's M.A.P. (Master Anti-aging Plan) to Growing Young, you can. Join critically-acclaimed, bestselling skin-care author Zia Wesley as she shares her holistic step-by-step processes to "youthing" naturally, from the inside out. REVIEWS: "Zia Wesley offers hope (and skin-care advice) for aging baby boomers" ~Daily Herald OTHER TITLES BY ZIA WESLEY: Zia's M.A.P to Basic Skin Care Zia's M.A.P to Skin Care for Men

A detailed holistic program for redesigning your relationship with your body and life, helping you feel younger, healthier, and more alive—regardless of your age Expanding on the principles in the landmark bestseller The Body Ecology Diet, this excitingly anticipated book provides a blueprint for restoring a vital friendship with our bodies as the years pass; and creating beauty, longevity, and well-being in ourselves and our world. Through diet, nutrition, and unique anti-aging therapies, Donna Gates—the originator of Body Ecology, a world-renowned system of healing—shows us how we can live fuller, healthier, more meaningful lives. What’s Inside: • Anti-aging remedies that will make you feel and look younger • The missing piece to all traditional diet programs • Insight into why we age and how we can prevent it • Little-known wellness secrets that address the stresses and pressures of our modern world • Superfood recommendations for increased energy, vitality, and disease prevention A fascinating blend of cutting-edge medical information, practical health advice, and spiritual wisdom, The Body Ecology Guide to Growing Younger is relevant for people of any age. This groundbreaking book suggests that we don’t simply have to age gracefully, we can age with panache.

From the bestselling author and PBS star, a brain healthy program to turn back the clock, and keep your mind sharp and your body fit. “Dr. Amen magically shows us that the aging of our brain need not match the aging of our bodies.”—Mehmet Oz, M.D. A healthy brain is the key to staying vibrant and alive for a long time, and in Use Your Brain to Change Your Age, bestselling author and brain expert Dr. Daniel G. Amen shares ten simple steps to boost your brain to help you live longer, look younger, and dramatically decrease your risk for Alzheimer’s disease. Over the last twenty years at Amen Clinics, Dr. Amen has performed more than 70,000 brain scans on patients from ninety different countries. His brain imaging work has taught him that our brains typically become less active with age and we become more vulnerable to memory problems and depression. Yet, one of the most exciting lessons he has learned is that with a little forethought and a brain-smart plan, you can slow, or even reverse, the aging process in the brain. Based on the approach that has helped thousands of people at Amen Clinics along with the most cutting-edge research, Dr. Amen’s breakthrough, easy-to-follow antiaging program shows you how to improve memory, focus, and energy; keep your heart and immune system strong; and reduce the outward signs of aging. By adopting the brain healthy strategies detailed in Use Your Brain to Change Your Age, you can outsmart your genes, put the brakes on aging, and even reverse the aging process. If you change your brain, you can change your life—and your age.