Volume 11 of the Handbook of Green Chemistry series identifies, explains and expands on green chemistry and engineering metrics, describing how the two work together, backed by numerous practical applications. Up-to-date and authoritative, this ready reference covers the development and application of sustainable chemistry along with engineering metrics in both academia and industry, providing the latest information on fundamental aspects of metrics, practical realizations and example case studies. Additionally, it outlines how metrics have been used to facilitate developments in sustainable and green chemistry. The different concepts of and approaches to metrics are applied to fundamental problems in chemistry and the focus is firmly placed on their use to promote the development and implementation of more sustainable and green chemistry and technology in the production of chemicals and related products. Starting with molecular design, followed by chemical route evaluation, chemical process metrics and product assessment, by the end readers will have a complete set of metrics to choose from as they move a chemical conception to final product. Of high interest to academics and chemists working in industry.

Volume 11 of the Handbook of Green Chemistry series identifies, explains and expands on green chemistry and engineering metrics, describing how the two work together, backed by numerous practical applications. Up-to-date and authoritative, this ready reference covers the development and application of sustainable chemistry along with engineering metrics in both academia and industry, providing the latest information on fundamental aspects of metrics, practical realizations and example case studies. Additionally, it outlines how metrics have been used to facilitate developments in sustainable and green chemistry. The different concepts of and approaches to metrics are applied to fundamental problems in chemistry and the focus is firmly placed on their use to promote the development and implementation of more sustainable and green chemistry and technology in the production of chemicals and related products. Starting with molecular design, followed by chemical route evaluation, chemical process metrics and product assessment, by the end readers will have a complete set of metrics to choose from as they move a chemical conception to final product. Of high interest to academics and chemists working in industry.

Contemporary Chemical Approaches for Green and Sustainable Drugs provides readers with the knowledge they need to integrate sustainable approaches into their work. Sections cover different aspects of green and sustainable drug development from design to disposal, including computer-aided drug design, green resourcing of drugs and drug candidates, an overview of the health concerns of pharmaceutical pollution, and a survey of potential chemical methods for its reduction. Drawing together the knowledge of a global team of experts, this book provides an inclusive overview of the chemical tools and approaches available for minimizing the negative environmental impact of current and newly developed drugs. This will be a useful guide for all academic and industrial researchers across green and sustainable chemistry, medicinal chemistry, environmental chemistry and pharmaceutical science. - Provides an integrative overview of the environmental risks of drugs and drug by products to support chemists in pre-emptively addressing these issues - Highlights the advantages of computer-aided drug design, green and sustainable sourcing, and novel methods for the production of safer, more effective drugs - Presents individual chapters written by renowned experts with diverse backgrounds - Reflects research in practice through selected case studies and extensive state-of-the-art reference sections to serve as a starting point in the design of any specialized environmentally-conscious medicinal chemistry project

Many modern surface coatings and adhesives are derived from fossil feedstocks. With fossil fuels becoming more polluting and expensive to extract as supplies dwindle, industry is turning increasingly to nature, mimicking natural solutions using renewable raw materials and employing new technologies. Highlighting sustainable technologies and applications of renewable raw materials within the framework of green and sustainable chemistry, circular economy and resource efficiency, this book provides a cradle-to-cradle perspective. From potential feedstocks to recycling/reuse opportunities and the de-manufacture of adhesives and solvents, green chemistry principles are applied to all aspects of surface coating, printing, adhesive and sealant manufacture. This book is ideal for students, researchers and industrialists working in green sustainable chemistry, industrial coatings, adhesives, inks and printing technologies.

Presents a wide-ranging overview of essential topics and recent advances in MCR chemistry Heterocycles are a central component in natural product chemistry, pharmaceuticals, agrochemicals, and material science. New synthetic methodologies integrating the sequencing of multicomponent reactions (MCRs) are today being used for the rapid synthesis of diversified heterocycles in just one step. Multicomponent Reactions towards Heterocycles presents an up-to-date summary MCR chemistry with a focus on the conjugation between modern synthetic methodologies and MCRs. Featuring contributions by leaders in the field, this comprehensive resource highlights applications of MCRs in natural products and intermediate synthesis, discusses current trends and future prospects in MCR chemistry, outlines novel multicomponent procedures, and more. The authors provide the practical information required for designing new reaction strategies and mechanisms, covering topics including MCR-based green synthetic methods, cyclization and cycloaddition reactions, heterocycle multicomponent syntheses in a continuous flow, catalytic alkynoyl generation, MCR synthesis of saturated heterocycles, and C–H functionalization and multicomponent reactions. Provides a thorough overview of heterocycles as input in multicomponent reactions Discusses recent advances in the field of MCR chemistry and progress in the synthesis and functionalization of heterocycles Demonstrates the use of MCRs to simplify synthetic design and achieve complexity and diversity in novel bioactive molecules Highlights examples of multicomponent polymerizations, target-oriented synthesis, and applications of MCR in medicinal chemistry Explains the methodology of using on-resin MCRs to produce heterocycle compounds Illustrating the key role of MCRs towards heterocycles in natural product synthesis, drug discovery, organic synthesis, and other applications, Multicomponent Reactions towards Heterocycles is required reading for synthetic chemists in academia and industry alike.

The principles of Green Chemistry aim to improve the sustainability of chemical processes and reduce the generation of hazardous substances. There has been great growth in the field over the past few years and the number of research groups working in this area is still increasing. Now one of the biggest challenges is to embed the Green Chemistry ideals of safety and sustainability as standard, both in industry and academia. In order to do this, it is important to create resources that detail different applications and approaches. Green Synthetic Processes and Procedures brings together expert contributors from across a number of areas of green synthesis to cover a diverse array of subjects. Providing a thorough overview of the current green synthetic toolbox, from biocatalysis to sonochemistry, this book is a useful resource for any chemist wishing to design cleaner and safer processes.

Quantifying the environmental impact of chemical technologies and products, and comparing alternative products and technologies in terms of their "greenness" is a challenging task. In order to characterise various aspects of a complex phenomenon, a number of different indicators are selected into a metric. This book outlines fundamental developments in chemistry and chemical technology that have led to the development of green chemistry, green chemical technology, and sustainable chemical technology concepts, and provide a foundation for the development of the corresponding metrics. It includes different approaches to metrics, and case study examples of their applications, and problems in practice. Green Chemistry Metrics is aimed at graduate students and researchers, practitioners and environmental managers in industry, metrics developers, and governmental agencies and NGOs in the area of environmental protection and sustainability. The main focus will be on chemical processes, however the book will be relevant to other industry sectors such as energy, electronics, healthcare, food and consumer products.