In this issue of Hematology/Oncology Clinics, guest editors Drs. Mary D. Chamberlin and Narjust Duma bring theirconsiderable expertise to the topic of Global Oncology: Disparities, Outcomes and Innovations Around the Globe. The first section of this issue is non-disease site-specific, covering broad topics that influence global health and oncology in various world regions, such as disparities, political unrest, the role of ASCO and ICEC and other organizations for education and research collaborations, access to training and innovations, etc. The second section is disease site-specific (lung, CNS, lymphoma, etc.), addressing approaches to prevention, access to treatment, survivorship, palliative care, and more. - Contains 16 relevant, practice-oriented topics including North America: disparities of care and the role of ASCO in addressing disparities of cancer care; evolving epidemiology: impact of lifestyle and prevention for breast and lung cancers; education and training models for remote learning: GlobalMedNet, GI Rising, Global Oncology for a new generation of fellows; breast cancer disparities: shared decision making and technological innovations; and more. - Provides in-depth clinical reviews on global oncology, offering actionable insights for clinical practice. - Presents the latest information on this timely, focused topic under the leadership of experienced editors in the field. Authors synthesize and distill the latest research and practice guidelines to create clinically significant, topic-based reviews.

In this issue of Hematology/Oncology Clinics, guest editors Drs. Jorge J. Castillo, Prashant Kapoor, and Shayna Sarosiek bring their considerable expertise to the topic of Waldenström Macroglobulinemia. Top experts in the field provide a focused update on the biology, diagnosis and management, and novel therapies for patients with Waldenström macroglobulinemia, a rare blood cell cancer characterized by an excess of abnormal white blood cells in the bone marrow. - Contains 14 practice-oriented topics including clinical implications of genomic profile in Waldenström macroglobulinemia; chemoimmunotherapy regimens in the frontline management of Waldenström macroglobulinemia; management of relapsed or refractory Waldenström macroglobulinemia; evaluation and management of aggressive transformation in Waldenström macroglobulinemia; management of Waldenström macroglobulinemia in limited-resource settings; and more. - Provides in-depth clinical reviews of Waldenström macroglobulinemia, offering actionable insights for clinical practice. - Presents the latest information on this timely, focused topic under the leadership of experienced editors in the field. Authors synthesize and distill the latest research and practice guidelines to create clinically significant, topic-based reviews.

In this issue of Hematology/Oncology Clinics, guest editors Drs. Bradley A. McGregor and Toni K. Choueiri bring their considerable expertise to the topic of Renal Cell Cancer. Top experts in the field cover key topics such as VHL and HIF at the center of renal cell cancer biology; immunobiology and metabolic pathways of renal cell cancer; hereditary renal cell cancer syndromes; the role of the pathologist in renal cell cancer; novel imaging in renal cell cancer; and more. - Contains 18 relevant, practice-oriented topics including the role of surgery in metastatic renal cell cancer; emerging biomarkers in metastatic renal cell cancer; choosing the right treatment for renal cell cancer of variant histology; novel targets in the treatment of renal cell cancer; and more. - Provides in-depth clinical reviews on renal cell cancer, offering actionable insights for clinical practice. - Presents the latest information on this timely, focused topic under the leadership of experienced editors in the field. Authors synthesize and distill the latest research and practice guidelines to create clinically significant, topic-based reviews.

In this issue of Hematology/Oncology Clinics, guest editors Drs. Caron A. Jacobson and Parth S. Shah bring their considerable expertise to the topic of CAR T-Cell Therapy. Top experts in the field discuss the multiple ways CAR T-cell therapy can be used to help fight a variety of cancers, such as diffuse large B-cell lymphoma (DLBCL), follicular lymphoma, mantle cell lymphoma, multiple myeloma, and B-cell acute lymphoblastic leukemia (ALL). - Contains 12 practice-oriented topics including CAR T-cells in aggressive B-cell lymphomas; CAR T-cells in multiple myeloma; CAR T-cells in AML; mechanisms of resistance of CAR T-cell therapy; the role of CAR T-cell therapy in the era of bispecific antibodies; and more. - Provides in-depth clinical reviews on CAR T-cell therapy, offering actionable insights for clinical practice. - Presents the latest information on this timely, focused topic under the leadership of experienced editors in the field. Authors synthesize and distill the latest research and practice guidelines to create clinically significant, topic-based reviews.

In this issue of Hematology/Oncology Clinics, guest editor Dr. Elizabeth K. O'Donnell brings her considerable expertise to the topic of Cancer Precursor Syndromes and Their Detection. Top experts focus on cancer precursors for different sites, with articles on the risk-benefit analysis of early interception; plasma cell precursors; early detection and interception of lung cancer, cervical cancer, GI cancers, skin cancer; and head and neck cancer; biomarkers and early detection; and more. - Contains 12 relevant, practice-oriented topics including clonal hematopoiesis of indeterminate potential (CHIP); prostate cancer: early detection and intervention; ductal carcinoma in situ; cancer prevention; and more. - Provides in-depth clinical reviews on cancer precursor syndromes and their detection, offering actionable insights for clinical practice. - Presents the latest information on this timely, focused topic under the leadership of experienced editors in the field. Authors synthesize and distill the latest research and practice guidelines to create clinically significant, topic-based reviews.

In this issue of Hematology/Oncology Clinics, guest editor David H. Ilson brings his considerable expertise to the topic of Malignancies of the Upper GI Tract. - Contains 12 relevant, practice-oriented topics including Advances in the Imaging of Esophageal and Gastroesophageal Junction Malignancies; Advances in Immunotherapy in Esophagogastric Cancer; Advances in Surgery and (Neo) Adjuvant Therapy in the Management of Pancreatic Cancer; Advances in the Surgical Management of Esophageal Cancer; and more. - Provides in-depth clinical reviews on malignancies of the upper GI tract, offering actionable insights for clinical practice. - Presents the latest information on this timely, focused topic under the leadership of experienced editors in the field. Authors synthesize and distill the latest research and practice guidelines to create clinically significant, topic-based reviews.

In this issue of Hematology/Oncology Clinics, guest editors Drs. Mary D. Chamberlin and Narjust Duma bring theirconsiderable expertise to the topic of Global Oncology: Disparities, Outcomes and Innovations Around the Globe. The first section of this issue is non-disease site-specific, covering broad topics that influence global health and oncology in various world regions, such as disparities, political unrest, the role of ASCO and ICEC and other organizations for education and research collaborations, access to training and innovations, etc. The second section is disease site-specific (lung, CNS, lymphoma, etc.), addressing approaches to prevention, access to treatment, survivorship, palliative care, and more. Contains 16 relevant, practice-oriented topics including North America: disparities of care and the role of ASCO in addressing disparities of cancer care; evolving epidemiology: impact of lifestyle and prevention for breast and lung cancers; education and training models for remote learning: GlobalMedNet, GI Rising, Global Oncology for a new generation of fellows; breast cancer disparities: shared decision making and technological innovations; and more. Provides in-depth clinical reviews on global oncology, offering actionable insights for clinical practice. Presents the latest information on this timely, focused topic under the leadership of experienced editors in the field. Authors synthesize and distill the latest research and practice guidelines to create clinically significant, topic-based reviews.