As information technology becomes an integral part of health care, it is important to collect and analyze data in a way that makes the information understandable and useful. Informatics tools--which help collect, organize, and analyze data--are essential to biomedical and health research and development. The field of cancer research is facing an overwhelming deluge of data, heightening the national urgency to find solutions to support and sustain the cancer informatics ecosystem. There is a particular need to integrate research and clinical data to facilitate personalized medicine approaches to cancer prevention and treatment--for example, tailoring treatment based on an individual patient's genetic makeup as well as that of the tumor --and to allow for more rapid learning from patient experiences. To further examine informatics needs and challenges for 21st century biomedical research, the IOM's National Cancer Policy Forum held a workshop February 27-28, 2012. The workshop was designed to raise awareness of the critical and urgent importance of the challenges, gaps and opportunities in informatics; to frame the issues surrounding the development of an integrated system of cancer informatics for acceleration of research; and to discuss solutions for transformation of the cancer informatics enterprise. Informatics Needs and Challenges in Cancer Research: Workshop Summary summarizes the workshop."--Publisher's description

Climate change poses many challenges that affect society and the natural world. With these challenges, however, come opportunities to respond. By taking steps to adapt to and mitigate climate change, the risks to society and the impacts of continued climate change can be lessened. The National Climate Assessment, coordinated by the U.S. Global Change Research Program, is a mandated report intended to inform response decisions. Required to be developed every four years, these reports provide the most comprehensive and up-to-date evaluation of climate change impacts available for the United States, making them a unique and important climate change document. The draft Fourth National Climate Assessment (NCA4) report reviewed here addresses a wide range of topics of high importance to the United States and society more broadly, extending from human health and community well-being, to the built environment, to businesses and economies, to ecosystems and natural resources. This report evaluates the draft NCA4 to determine if it meets the requirements of the federal mandate, whether it provides accurate information grounded in the scientific literature, and whether it effectively communicates climate science, impacts, and responses for general audiences including the public, decision makers, and other stakeholders.

Summarizes the science of climate change and impacts on the United States, for the public and policymakers.

The U.S. Global Change Research Program (USGCRP) is an interagency program, established by the Global Change Research Act (GCRA) of 1990, mandated by Congress to "assist the Nation and the world to understand, assess, predict, and respond to human-induced and natural processes of global change". Since the USGCRP began, scientific understanding of global change has increased and the information needs of the nation have changed dramatically. A better understanding of what is changing and why can help decision makers in the public and private sectors cope with ongoing change. Accomplishments of the U.S. Global Change Research Program highlights the growth of global change science in the quarter century that the USGCRP has been in existence, and documents some of its contributions to that growth through its primary functions of interagency planning and coordination, and of synthesis of research and practice to inform decision making.

How can we understand and rise to the environmental challenges of global change? One clear answer is to understand the science of global change, not solely in terms of the processes that control changes in climate and the composition of the atmosphere, but in how ecosystems and human society interact with these changes. In the last two decades of the twentieth century, a number of such research effortsâ€"supported by computer and satellite technologyâ€"have been launched. Yet many opportunities for integration remain unexploited, and many fundamental questions remain about the earth's capacity to support a growing human population. This volume encourages a renewed commitment to understanding global change and sets a direction for research in the decade ahead. Through case studies the book explores what can be learned from the lessons of the past 20 years and what are the outstanding scientific questions. Highlights include: Research imperatives and strategies for investigators in the areas of atmospheric chemistry, climate, ecosystem studies, and human dimensions of global change. The context of climate change, including lessons to be gleaned from paleoclimatology. Human responses toâ€"and forcing ofâ€"projected global change. This book offers a comprehensive overview of global change research to date and provides a framework for answering urgent questions.

Global Change and the Earth System describes what is known about the Earth system and the impact of changes caused by humans. It considers the consequences of these changes with respect to the stability of the Earth system and the well-being of humankind; as well as exploring future paths towards Earth-system science in support of global sustainability. The results presented here are based on 10 years of research on global change by many of the world's most eminent scholars. This valuable volume achieves a new level of integration and interdisciplinarity in treating global change.

This book gives an overview of the state of research in fields pertaining to the detection, understanding and prediction of global change impacts in mountain regions. More than sixty contributions from paleoclimatology, cryospheric research, hydrology, ecology, and development studies are compiled in this volume, each with an outlook on future research directions. The book will interest meteorologists, geologists, botanists and climatologists.