Yeast Genetics: Methods and Protocols is a collection of methods to best study and manipulate Saccharomyces cerevisiae, a truly genetic powerhouse. The simple nature of a single cell eukaryotic organism, the relative ease of manipulating its genome and the ability to interchangeably exist in both haploid and diploid states have always made it an attractive model organism. Genes can be deleted, mutated, engineered and tagged at will. Saccharomyces cerevisiae has played a major role in the elucidation of multiple conserved cellular processes including MAP kinase signaling, splicing, transcription and many others. Written in the successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible protocols and notes on troubleshooting and avoiding known pitfalls. Authoritative and easily accessible, Yeast Genetics: Methods and Protocols will provide a balanced blend of classic and more modern genetic methods relevant to a wide range of research areas and should be widely used as a reference in yeast labs.

Englishman Robert Livermore jumped ship in Southern California in 1822, yet just 15 years later became the respected owner of the 40,000-acre Las Positas land grant. Here he built his new Californio wife an adobe house in 1839. The wealth that flowed into California during the gold rush allowed Livermore to import a two-story house around the Horn, but entrepreneurs and squatters flowed in as well. Nathaniel Patterson opened the first hotel in the old Livermore adobe, frequented by miners on their way from the South Bay to the Sierra gold mines. Laddsville, a village built where the roads to Stockton and Dublin met, was also a going concern until the Central Pacific pushed over the Altamont Pass. On this line grew the town founded by William Mendenhall in 1869, named for pioneer Livermore, who had died more than a decade earlier. Soon Livermore became the valley's commercial center for hay, wheat, barley, wine grapes, and ranching.

This issue of Heart Failure Clinics--edited by Dr. Eduardo Bossone--will cover The Right Heart Pulmonary Circulation Unit. Topics include Pathophysiology, Increased Systemic versus Increased Pulmonary Pressures, Pulmonary Arterial Hypertension, Right Heart Pulmonary Circulation Unit in Connective Tissue Disease, Right Heart Pulmonary Circulation Unit in Congenital Heart Diseases, Pulmonary Hypertension and Heart Failure, Right Heart Pulmonary Circulation Unit in Cardiomyopathies and Storage Diseases, Pulmonary Hypertension, Right Heart Pulmonary Circulation Unit at High Altitude, Chronic Thromboembolic Pulmonary Hypertension, Combining Invasive and Non-Invasive Evaluation for the Diagnosis of Pulmonary Hypertension, Imaging the Right Heart Pulmonary Circulation Unit: The Role of Ultrasound, Imaging the Right Heart Pulmonary Circulation Unit: The Role of CT and MRI, Biomarkers in Pulmonary Hypertension, Pulmonary Hypertension Related to Diffuse Parenchymal Lung Disease, Chronic Right Heart Failure, Exercise Training and Rehabilitation in Pulmonary Hypertension, and Right Heart Circulation Unit and Left Heart Valvular Diseases.

Geriatric Psycho-Oncology is a comprehensive handbook that provides best practice models for the management of psychological, cognitive, and social outcomes of older adults living with cancer and their families. Chapters cover a wide range of topics including screening tools and interventions, psychiatric emergencies and disorders, physical symptom management, communication issues, and issues specific to common cancer sites. A resource section is appended to provide information on national services and programs. This book features contributions from experts designed to help clinicians review, anticipate and respond to emotional issues that often arise in the context of treating older cancer patients. Numerous cross-references and succinct tables and figures make this concise reference easy to use. Geriatric Psycho-Oncology is an ideal resource for helping oncologists and nurses recognize when it may be best to refer patients to their mental health colleagues and for those who are establishing or adding psychosocial components to existing clinics.

Networking for Nerds provides a step-by-step guide to understanding how to access hidden professional opportunities through networking. With an emphasis on practical advice on how and why to network, you will learn how to formulate and execute a strategic networking plan that is dynamic, multidimensional, and leverages social media platforms and other networking channels. An invaluable resource for both established and early-career scientists and engineers (as well as networking neophytes!), Networking for Nerds offers concrete insight on crafting professional networks that are mutually beneficial and support the advancement of both your career goals and your scholarly ambitions. “Networking” does not mean going to one reception or speaking with a few people at one conference, and never contacting them again. Rather, “networking” involves a spectrum of activities that engages both parties, ensures everyone’s value is appropriately communicated, and allows for the exploration of a win-win collaboration of some kind. Written by award-winning entrepreneur and strategic career planning expert Alaina G. Levine, Networking for Nerds is an essential resource for anyone working in scientific and engineering fields looking to enhance their professional planning for a truly fulfilling, exciting, and stimulating career. professional planning for a truly fulfilling, exciting, and stimulating career.Networking for Nerds provides a step-by-step guide to understanding how to access hidden professionalopportunities through networking. With an emphasis on practical advice on how and why to network, youwill learn how to formulate and execute a strategic networking plan that is dynamic, multidimensional, andleverages social media platforms and other networking channels.An invaluable resource for both established and early-career scientists and engineers (as well as networkingneophytes!), Networking for Nerds offers concrete insight on crafting professional networks that aremutually beneficial and support the advancement of both your career goals and your scholarly ambitions.“Networking” does not mean going to one reception or speaking with a few people at one conference, andnever contacting them again. Rather, “networking” involves a spectrum of activities that engages bothparties, ensures everyone’s value is appropriately communicated, and allows for the exploration of a win-wincollaboration of some kind.Written by award-winning entrepreneur and strategic career planning expert Alaina G. Levine, Networking forNerds is an essential resource for anyone working in scientific and engineering fields looking to enhance theirprofessional planning for a truly fulfilling, exciting, and stimulating career.