Modern transportation allows people, animals, and plants-and the pathogens they carry-to travel more easily than ever before. The ease and speed of travel, tourism, and international trade connect once-remote areas with one another, eliminating many of the geographic and cultural barriers that once limited the spread of disease. Because of our global interconnectedness through transportation, tourism and trade, infectious diseases emerge more frequently; spread greater distances; pass more easily between humans and animals; and evolve into new and more virulent strains. The IOM's Forum on Microbial Threats hosted the workshop "Globalization, Movement of Pathogens (and Their Hosts) and the Revised International Health Regulations" December 16-17, 2008 in order to explore issues related to infectious disease spread in a "borderless" world. Participants discussed the global emergence, establishment, and surveillance of infectious diseases; the complex relationship between travel, trade, tourism, and the spread of infectious diseases; national and international policies for mitigating disease movement locally and globally; and obstacles and opportunities for detecting and containing these potentially wide-reaching and devastating diseases. This document summarizes the workshop.

This book provides an easy to use, practical, yet comprehensive resource for family practitioners to use in the daily struggle against infectious diseases. It discusses vaccines and preventive measures as well as information on how to reduce the incidence of antimicrobial-resistant organisms by judiciously prescribing antibiotics and informing patients about the appropriate use of these agents. This up-to-date overview is a one stop source for evidence-based guidelines.

Praise for the previous edition: “Approaches near perfection...This is an excellent introduction to infectious diseases by a group of authors who take a straightforward and bullet-point approach to thinking and talking about clinical issues...”—Doody’s Reviews Updated second edition of the concise but comprehensive handbook covering clinical infectious disease for students, residents, primary care medical providers, nurses, and PAs. Written in outline format with short, focused chapters, the book presents a systematic method for understanding basic mechanisms, establishing a diagnosis, and implementing appropriate treatment for commonly encountered problems. Essentials of Clinical Infectious Diseases, Second Edition begins with a general framework covering basics of clinical reasoning, antimicrobial agents and microbiology, and antimicrobial stewardship. Individual chapters devoted to the broad range of infectious diseases and topics are organized by body system and feature targeted presentation of pathogenesis and risk factors, microbial causes, clinical manifestations, patient work-up, diagnostic criteria, and medical, antimicrobial, and surgical management. The book also addresses important related topics including fever and neutropenia, approach to evaluating ectoparasite-related infections, infectious diseases approach to sepsis, travel medicine, and basics of infection control and hospital epidemiology. Designed for busy practitioners at any level looking to sharpen the clinical problem-solving skills required to provide the highest quality care to patients with infectious diseases. Key Features: Includes a new bonus chapter that addresses severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), also known as coronavirus disease 2019 (COVID-19) Presents core clinical infectious disease topics in concise easy-to-read format Revised and updated to reflect recent developments in the field consistent with evidence-based literature and current clinical practice guidelines 6 new chapters on lyme disease, anorectal infections, travel medicine, dental infections, antimicrobial stewardship, and clinical reasoning and statistics Focus on the approach to evaluation and management of the patient Incorporates essential antimicrobial therapy information with adult, pediatric, and OB-GYN dosing considerations

Infectious diseases are the leading cause of death globally, particularly among children and young adults. The spread of new pathogens and the threat of antimicrobial resistance pose particular challenges in combating these diseases. Major Infectious Diseases identifies feasible, cost-effective packages of interventions and strategies across delivery platforms to prevent and treat HIV/AIDS, other sexually transmitted infections, tuberculosis, malaria, adult febrile illness, viral hepatitis, and neglected tropical diseases. The volume emphasizes the need to effectively address emerging antimicrobial resistance, strengthen health systems, and increase access to care. The attainable goals are to reduce incidence, develop innovative approaches, and optimize existing tools in resource-constrained settings.