Genes exist predominantly as families with related structures and functions, particularly within eucaryotic organisms. The isozyme concept was first introduced by Markert and MØller in 1959, and has formed the basis of large numbers of scientific investigations and conferences on gene families since that time. This volume is based on presentations made by invited Plenary and Symposia speakers at the Eighth International Congress on Isozymes on the topic of Gene Families: Structure, Function, Genetics and Evolution. The major themes for the Congress were in the following areas: molecular evolution; population genetics; enzymology; Australian fauna; biomedical aspects; molecular genetics; cellular compartmentation; gene regulation; and developmental genetics.

First multi-year cumulation covers six years: 1965-70.

Organisms frequently synthesize enzymes in multiple molecular forms to catalyze the same basic biochemical reactions. Each of these enzymes exhibit somewhat different kinetic properties and perhaps, are also located in a specific part of the metabolic structure of the cell. This isozymic multiplicity only emphasizes the biochemical versatility and refinement of the genetic-enzyme structure of organisms.Since the isozyme concept was formulated some thirty-five years ago, and especially after the advent of transgenic technology, the deep interest in the area has led to thousands of research investigations and many international conferences on the subject. This volume is a collection of selected oral presentations from one such conference, which is by now well-known.Topics includes: isozymes in population and evolution genetics, isozyme markers in gene mapping, isozymes in plant genetics, role of isozymes for normal physiology, the use of isozymes in human population biology, molecular organization and developmental regulation of isozymes and other related topics.