A comprehensive review of all known immune mechanisms for medically important fungal pathogens from the organ perspectives of the human body. This authoritative guide is organized by organ system, as one particular fungus can have several different effects.

A comprehensive review of all known immune mechanisms for medically important fungal pathogens from the organ perspectives of the human body. This authoritative guide is organized by organ system, as one particular fungus can have several different effects.

This text covers all aspects of the immunology of fungal infection. Beyond the basics, coverage includes recent developments in innate and adaptive immunological mechanisms involved in the host response to fungal infection. The volume’s topical sections provide an immunological perspective on the cells, soluble factors and receptors involved in recognising and combating fungal infections. Discussion includes descriptions of immunity to specific pathogens, immune-escape mechanisms used by fungi, and therapeutic strategies.

This book illustrates, that the fungal cell wall is critical for the biology and ecology of all fungi and especially for human fungal pathogens. Readers will learn, that the composition of the fungal cell wall is a unique structure, which cannot be found in the human host. Consequently, the chapters outline, how the immune systems of both animals and humans have evolved to recognize conserved and unique elements of the fungal cell wall. As an application example, the authors also show, that the three-dimensional structures of the cell wall are excellent targets for the development of antifungal agents and chemotherapeutic strategies. With the combination of biological findings and medical outlooks, this volume is a fascinating read for scientists, clinicians and biomedical students.

Stresses molecular and biochemical studies of opportunistic and frank fungal pathogens! This book gives a comprehensive overview of human pathogenic fungi that offers a current and concise survey of virulence factors, host responses and recognition, treatment and diagnosis of infections, invasive enzymes, intracellular survival, morphogenesis, adaptation, and properties of major fungal pathogens that contribute to disease. Focuses on human fungal infections, including candidiasis, pneumocystosis, aspergillosis, and cryptococcosis. With over 3700 references to accommodate continuing study, Fungal Pathogenesis covers natural and acquired immunity, vaccine development, and immune reconstitution outlines rapid identification of major mycoses utilizing antigen capture and molecular assays details signaling and phenotypic switching discusses the value of genomics in validation highlights state-of-the-art molecular methodologies to study disease-causing organisms describes available and potential antifungal drug targets and drug development considers predicting the consequences of drug resistance on patient management presents topical observations on strain typing and variation and more! Containing research into the virulence, immunity, diagnosis, and therapy of most common fungal infections, Fungal Pathogenesis is an unparalleled reference for microbiologists, virologists, pathologists and phytopathologists, infectious disease specialists, molecular and cell biologists, biochemists, immunologists, medical mycologists, biotechnologists, and geneticists, and an exceptional text for upper-level undergraduate, graduate, and medical school students in these disciplines.

Concise, up-to-date guide to the clinical manifestations,laboratory diagnosis and management of superficial, subcutaneousand systemic fungal infections "I would recommend this book to all microbiologists andclinicians regularly dealing with patients suffering from fungalinfections." Journal of Medical Microbiology WHY BUY THIS BOOK? Thorough update of significant developments in the diagnosisand management of fungal infections Up-to-date drug and dosage recommendations updated in line withcurrent guidelines New feature: epidemiology and prevention section in eachchapter plus further reading lists of key papers New feature: algorithms in each section on management andtreatment of key fungal infections Problem-orientated to help clinician make best use oftime-consuming laboratory investigations This title is now available for the PDA, powered by Skyscape- to buy your copy click here