Fundamentals of In Vivo Magnetic Resonance Authoritative reference explaining why and how the most important, radiation-free technique for elucidating tissue properties in the body works In Vivo Magnetic Resonance helps readers develop an understanding of the fundamental physical processes that take place inside the body that can be probed by magnetic resonance imaging (MRI) and magnetic resonance spectroscopy (MRS), uniquely bridging the gap between the physics of magnetic resonance (MR) image formation and the in vivo processes that influence the detected signals, thereby equipping the reader with the mathematical tools essential to study the spin interactions leading to various contrast mechanisms. With a focus on clinical relevance, this book equips readers with practical knowledge that can be directly applied in medical settings, enabling informed decision-making and advancements in the field of medical imaging. The material arises from the lecture notes for a Stanford University Department of Radiology course taught for over 15 years. Aided by clever illustrations, the book takes a step-by-step approach to explain complex concepts in a comprehensible manner. Readers can test their understanding by working on approximately 60 sample problems. Written by two highly qualified authors with significant experience in the field, In Vivo Magnetic Resonance includes information on: The fundamental imaging equations of MRI Quantum elements of magnetic resonance, including linear vector spaces, Dirac notation, Hilbert Space, Liouville Space, and associated mathematical concepts Nuclear spins, covering external and internal interactions, chemical shifts, dipolar coupling, J-coupling, the spin density operator, and the product operator formalism In vivo MR spectroscopy methods MR relaxation theory and the underlying sources of image contrast accessible via modern clinical MR imaging techniques With comprehensive yet accessible coverage of the subject and a wealth of learning resources included throughout, In Vivo Magnetic Resonance is an ideal text for graduate students in the fields of physics, biophysics, biomedical physics, and materials science, along with lecturers seeking classroom aids.

Fundamentals of Medical Imaging, second edition, is an invaluable technical introduction to each imaging modality, explaining the mathematical and physical principles and giving a clear understanding of how images are obtained and interpreted. Individual chapters cover each imaging modality – radiography, CT, MRI, nuclear medicine and ultrasound – reviewing the physics of the signal and its interaction with tissue, the image formation or reconstruction process, a discussion of image quality and equipment, clinical applications and biological effects and safety issues. Subsequent chapters review image analysis and visualization for diagnosis, treatment and surgery. New to this edition: • Appendix of questions and answers • New chapter on 3D image visualization • Advanced mathematical formulae in separate text boxes • Ancillary website containing 3D animations: www.cambridge.org/suetens • Full colour illustrations throughout Engineers, clinicians, mathematicians and physicists will find this an invaluable aid in understanding the physical principles of imaging and their clinical applications.

Quantitative Magnetic Resonance Imaging is a 'go-to' reference for methods and applications of quantitative magnetic resonance imaging, with specific sections on Relaxometry, Perfusion, and Diffusion. Each section will start with an explanation of the basic techniques for mapping the tissue property in question, including a description of the challenges that arise when using these basic approaches. For properties which can be measured in multiple ways, each of these basic methods will be described in separate chapters. Following the basics, a chapter in each section presents more advanced and recently proposed techniques for quantitative tissue property mapping, with a concluding chapter on clinical applications. The reader will learn: - The basic physics behind tissue property mapping - How to implement basic pulse sequences for the quantitative measurement of tissue properties - The strengths and limitations to the basic and more rapid methods for mapping the magnetic relaxation properties T1, T2, and T2* - The pros and cons for different approaches to mapping perfusion - The methods of Diffusion-weighted imaging and how this approach can be used to generate diffusion tensor - maps and more complex representations of diffusion - How flow, magneto-electric tissue property, fat fraction, exchange, elastography, and temperature mapping are performed - How fast imaging approaches including parallel imaging, compressed sensing, and Magnetic Resonance - Fingerprinting can be used to accelerate or improve tissue property mapping schemes - How tissue property mapping is used clinically in different organs - Structured to cater for MRI researchers and graduate students with a wide variety of backgrounds - Explains basic methods for quantitatively measuring tissue properties with MRI - including T1, T2, perfusion, diffusion, fat and iron fraction, elastography, flow, susceptibility - enabling the implementation of pulse sequences to perform measurements - Shows the limitations of the techniques and explains the challenges to the clinical adoption of these traditional methods, presenting the latest research in rapid quantitative imaging which has the possibility to tackle these challenges - Each section contains a chapter explaining the basics of novel ideas for quantitative mapping, such as compressed sensing and Magnetic Resonance Fingerprinting-based approaches

Combines clear and concise discussions of key NMR concepts with succinct and illustrative examples Designed to cover a full course in Nuclear Magnetic Resonance (NMR) Spectroscopy, this text offers complete coverage of classic (one-dimensional) NMR as well as up-to-date coverage of two-dimensional NMR and other modern methods. It contains practical advice, theory, illustrated applications, and classroom-tested problems; looks at such important ideas as relaxation, NOEs, phase cycling, and processing parameters; and provides brief, yet fully comprehensible, examples. It also uniquely lists all of the general parameters for many experiments including mixing times, number of scans, relaxation times, and more. Nuclear Magnetic Resonance Spectroscopy: An Introduction to Principles, Applications, and Experimental Methods, 2nd Edition begins by introducing readers to NMR spectroscopy - an analytical technique used in modern chemistry, biochemistry, and biology that allows identification and characterization of organic, and some inorganic, compounds. It offers chapters covering: Experimental Methods; The Chemical Shift; The Coupling Constant; Further Topics in One-Dimensional NMR Spectroscopy; Two-Dimensional NMR Spectroscopy; Advanced Experimental Methods; and Structural Elucidation. Features classical analysis of chemical shifts and coupling constants for both protons and other nuclei, as well as modern multi‐pulse and multi-dimensional methods Contains experimental procedures and practical advice relative to the execution of NMR experiments Includes a chapter-long, worked-out problem that illustrates the application of nearly all current methods Offers appendices containing the theoretical basis of NMR, including the most modern approach that uses product operators and coherence-level diagrams By offering a balance between volumes aimed at NMR specialists and the structure-determination-only books that focus on synthetic organic chemists, Nuclear Magnetic Resonance Spectroscopy: An Introduction to Principles, Applications, and Experimental Methods, 2nd Edition is an excellent text for students and post-graduate students working in analytical and bio-sciences, as well as scientists who use NMR spectroscopy as a primary tool in their work.

Localization 1. C.S. Bosch, J.J.H. Ackerman, St. Louis, MO/USA SurfaceCoil Spectroscopy 2. P. Styles, Oxford, UK Rotating Frame Spectroscopyand Spectroscopic Imaging 3. P.A. Bottomley, Schenectady, NY/USA DepthResolved Surface Coil Spectroscopy (Dress) 4. R.J. Ordidge, J.A. Helpern, Detroit, MI/USA Image Guided Volume Selective Spectroscopy: A Comparison of Techniques for In-Vivo 31P NMR Spectroscopy of Human Brain 5. M. Decorps, D. Bourgeois, Grenoble, France Localized Spectroscopy Using Static Magnetic Field Gradients: Comparison of Techniques 6. J.A. den Hollander, P.R. Luyten, Ad J.H. Marien, Best, The Netherlands 1H NMR Spectroscopy and Spectroscopic Imaging of the Human Brain Spectral Editing and Kinetic Measurements 7. H.P. Hetherington, Birmingham, AL/USA Homo- and Heteronuclear Editing in Proton Spectroscopy 8. D. Freeman, R. Hurd, Fremont, CA/USA Metabolite Specific Methods Using Double Quantum Coherence Transfer Spectroscopy 9. B.A. Berkowitz, Research Triangle Park, NC/USA Two-Dimensional Correlated Spectroscopy In-Vivo 10. G. Navon, Tel Aviv, Israel; T. Kushnir, Tel Hashomer, Israel; N. Askenasy, O. Kaplan, Tel Aviv, Israel Two-Dimensional 31P-1H Correlation Spectroscopy in Intact Organs and Their Extracts 11. M. Rudin, A. Sauter, Basel, Switzerland Measurement of Reaction Rates In Vivo Using Magnetization Transfer Techniques.

In the past few decades, Magnetic Resonance Imaging (MRI) has become an indispensable tool in modern medicine, with MRI systems now available at every major hospital in the developed world. But for all its utility and prevalence, it is much less commonly understood and less readily explained than other common medical imaging techniques. Unlike optical, ultrasonic, X-ray (including CT), and nuclear medicine-based imaging, MRI does not rely primarily on simple transmission and/or reflection of energy, and the highest achievable resolution in MRI is orders of magnitude smaller that the smallest wavelength involved. In this book, MRI will be explained with emphasis on the magnetic fields required, their generation, their concomitant electric fields, the various interactions of all these fields with the subject being imaged, and the implications of these interactions to image quality and patient safety. Classical electromagnetics will be used to describe aspects from the fundamental phenomenon of nuclear precession through signal detection and MRI safety. Simple explanations and Illustrations combined with pertinent equations are designed to help the reader rapidly gain a fundamental understanding and an appreciation of this technology as it is used today, as well as ongoing advances that will increase its value in the future. Numerous references are included to facilitate further study with an emphasis on areas most directly related to electromagnetics.

New edition explores contemporary MRI principles and practices Thoroughly revised, updated and expanded, the second edition of Magnetic Resonance Imaging: Physical Principles and Sequence Design remains the preeminent text in its field. Using consistent nomenclature and mathematical notations throughout all the chapters, this new edition carefully explains the physical principles of magnetic resonance imaging design and implementation. In addition, detailed figures and MR images enable readers to better grasp core concepts, methods, and applications. Magnetic Resonance Imaging, Second Edition begins with an introduction to fundamental principles, with coverage of magnetization, relaxation, quantum mechanics, signal detection and acquisition, Fourier imaging, image reconstruction, contrast, signal, and noise. The second part of the text explores MRI methods and applications, including fast imaging, water-fat separation, steady state gradient echo imaging, echo planar imaging, diffusion-weighted imaging, and induced magnetism. Lastly, the text discusses important hardware issues and parallel imaging. Readers familiar with the first edition will find much new material, including: New chapter dedicated to parallel imaging New sections examining off-resonance excitation principles, contrast optimization in fast steady-state incoherent imaging, and efficient lower-dimension analogues for discrete Fourier transforms in echo planar imaging applications Enhanced sections pertaining to Fourier transforms, filter effects on image resolution, and Bloch equation solutions when both rf pulse and slice select gradient fields are present Valuable improvements throughout with respect to equations, formulas, and text New and updated problems to test further the readers' grasp of core concepts Three appendices at the end of the text offer review material for basic electromagnetism and statistics as well as a list of acquisition parameters for the images in the book. Acclaimed by both students and instructors, the second edition of Magnetic Resonance Imaging offers the most comprehensive and approachable introduction to the physics and the applications of magnetic resonance imaging.