The Frozen Section Library series provides concise, user-friendly, site specific handbooks that are well illustrated and highlight the pitfalls, artifacts and differential diagnosis issues that arise in the hurried frozen section scenario. Frozen Section Library: Breast provides an easy reference and pocket book about the nuances of adequately handling breast specimens in a fashion that meets the increasingly complex environment of breast pathology. The pros and cons of frozen section versus use of touch imprint as well as related quality assurance requirements are addressed. Other less common uses of intraoperative evaluation, such as diagnosis and margin evaluation are described. The volume includes recommended guidelines for evaluation and documentation of specific gross pathologic features, in conjunction with radiological imaging. Techniques and protocols for such examinations are illustrated. The volume closes with an overview of the newly published guidelines for handling a variety of breast specimens, which are intended to be used for assessment of predictive factors. Syed K. Mohsin, M.D. is the Head of Breast Pathology and Medical Director, Immunohistochemistry, Riverside Methodist Hospital, Columbus, OH

The Frozen Section Library series provides concise, user-friendly, site specific handbooks that are well illustrated and highlight the pitfalls, artifacts and differential diagnosis issues that arise in the hurried frozen section scenario. Frozen Section Library: Breast provides an easy reference and pocket book about the nuances of adequately handling breast specimens in a fashion that meets the increasingly complex environment of breast pathology. The pros and cons of frozen section versus use of touch imprint as well as related quality assurance requirements are addressed. Other less common uses of intraoperative evaluation, such as diagnosis and margin evaluation are described. The volume includes recommended guidelines for evaluation and documentation of specific gross pathologic features, in conjunction with radiological imaging. Techniques and protocols for such examinations are illustrated. The volume closes with an overview of the newly published guidelines for handling a variety of breast specimens, which are intended to be used for assessment of predictive factors. Syed K. Mohsin, M.D. is the Head of Breast Pathology and Medical Director, Immunohistochemistry, Riverside Methodist Hospital, Columbus, OH

The Frozen Section Library series provides concise, user-friendly, site specific handbooks that are well illustrated and highlight the pitfalls, artifacts and differential diagnosis issues that arise in the hurried frozen section scenario. Frozen Section Library: Lymph Nodes highlights the usefulness of techniques such as touch preparation cytology and fine needle aspiration (FNA) cytology, as well as FNA biopsy. This fascicle also suggests proper handling for subsequent ancillary studies, including flow cytometric, cytogenetic, and molecular studies. Special emphasis is given to the limitations of frozen section diagnosis in lymph node pathology. All chapters are written by experts in their fields and include the most up to date scientific information. This book serves as a very useful resource for physicians in the frozen section room and in intra-operative consultation situations dealing with, and interested in, this very complex field of diagnostic pathology. Frozen Section Library: Lymph Nodes is of great value to pathologists, residents, and fellows who diagnose pathologic processes involving lymph nodes. Cherie H. Dunphy, M.D. is Professor of Pathology and Laboratory Medicine, Executive Director of Hematopathology and Hematopathology Fellowship Department of Pathology and Laboratory Medicine University of North Carolina Chapel Hill, NC.

Frozen sections are diagnosed by the pathologist while a patient is undergoing surgery, often under general anesthesia, for the purpose of rapid diagnosis which may be used to make immediate treatment decisions or to confirm that diagnostic tissues have been sampled for further study. As a result, frozen section diagnosis is often a highly demanding situation for the pathologist who must render a diagnosis quickly and is a basis for critical decisions to the surgeon. In addition to the need for rapid recall of differential diagnoses, there are many pitfalls and artifacts that add to the risk of frozen section diagnosis that are not present with permanent sections of fully processed tissues that can be examined in a more leisurely fashion. Most standard pathology textbooks, both general and subspecialty, largely ignore the topic of frozen section. Few textbooks have ever focused exclusively on frozen section diagnosis and those textbooks that have done so are now out-of-date and have limited numbers of black and white figures. Frozen Section Library: Pleura provides a convenient, user-friendly handbook to expedite use when performing intraoperative consultations on pleural specimens. This book is divided into chapters that emphasize the common questions that a pathologist must answer on frozen section examination and the pitfalls associated with those specific diagnoses. The diagnostic issues impacting immediate surgical decision-making are color illustrated and discussed succinctly, including a complex array of primary and secondary neoplasms of the pleura that have overlapping histologic features and the well-known problems of reactive atypia versus cancer in pleural tissue. As a handbook for practicing pathologists, this book is an indispensable aid to diagnosis and avoiding dangers in one of the most challenging situations that pathologists encounter. Rapid consideration of differential diagnoses and how to avoid traps caused by frozen section artifacts will be readily accessible to the users of this handbook. Tables provide guidance for various categories of differential diagnoses. Currently, there is no other up-to-date single-source reference specifically focused on frozen sections of the pleura. This book will be highly valuable to practicing surgical pathologists, both community and academic, and to pathology residents and fellows. The perspectives provided will also be valuable to thoracic surgeons and especially to surgery residents and thoracic surgery fellows who must answer questions about pathology and frozen section on their board examinations.

As a handbook for practicing pathologists, this book will be an indispensable aid to diagnosis and avoiding dangers in one of the most challenging situations that pathologists encounter. Rapid consideration of differential diagnoses and how to avoid traps caused by frozen section artifacts will be readily accessible to the users of this handbook. Currently, there is no other up-to-date single-source reference specifically focused on frozen sections of the lower gastrointestinal tract.

Frozen sections are performed while a patient is undergoing surgery as a basis for making an immediate diagnosis that will impact treatment decisions. Frozen section diagnosis is often a highly demanding situation for the pathologist who must render a diagnosis quickly, based on careful gross examination of specimens to select optimal areas for microscopic examination. The Frozen Section Library series will provide concise, user-friendly, site specific handbooks that are well illustrated and highlight the pitfalls, artifacts and differential diagnosis issues that arise in the hurried frozen section scenario. Donna M. Coffey, M.D., is Assistant Professor, Department of Pathology and Laboratory Medicine, The Methodist Hospital, Houston, Texas and Weill Medical College of Cornell University, New York, New York. Ibrahim Ramzy, M.D., is Professor of Pathology - Laboratory Medicine & Obstetrics-Gynecology, University of California, Irvine, California and Adjunct Professor of Pathology, Baylor College of Medicine, Houston, Texas.

Frozen sections of the pancreas are performed to assess resectability, for tissue confirmation and to assess margins. The clinical implications of an accurate frozen section diagnosis are dramatic as far as type and extent of surgery performed. "Frozen Section of the Pancreas" will provide a concise pictorial compendium to facilitate intraoperative consultations on pancreas specimens. The book will be 5x8 and is estimated to be 200-250 pages with 100-150 color figures. This user-friendly handbook will be divided into chapters that emphasize the common questions a pathologist must answer on frozen section examination and will provide guidance for the differential diagnosis of various histologic patterns. The purpose of this book is to aid in the timely frozen section diagnosis of pancreatic lesions by using a broad array of illustrations, which would reinforce one’s visual memory, and a condensed text, useful for rapid review of main diagnostic features. Currently, there is no other up-to-date, single-source reference specifically focused on frozen sections of the pancreas.