Frozen sections are performed while a patient is undergoing surgery as a basis for making an immediate diagnosis that will impact treatment decisions. Frozen section diagnosis is often a highly demanding situation for the pathologist who must render a diagnosis quickly for the patient and surgeon. The Frozen Section Library series will provide concise, user-friendly, site specific handbooks that are well illustrated and highlight the pitfalls, artifacts and differential diagnosis issues that arise in the hurried frozen section scenario.

Frozen sections are performed while a patient is undergoing surgery as a basis for making an immediate diagnosis that will impact treatment decisions. Frozen section diagnosis is often a highly demanding situation for the pathologist who must render a diagnosis quickly for the patient and surgeon. The Frozen Section Library series will provide concise, user-friendly, site specific handbooks that are well illustrated and highlight the pitfalls, artifacts and differential diagnosis issues that arise in the hurried frozen section scenario.

"Intraoperative frozen sections presents diagnostic challenges involved in the evaluation in the pathology lab of specimens obtained during surgery through the case experience of expert pathologists. Sixty three problems cover the wide range of approximately of problems encountered in intraoperative consultations. Each presentation provides the case information as presented to the consultant, the evaluation and analysis of the specimen, discussion of the results and teaching points observed in the case, and an overall comment providing additional context for the diagnostic problem that has been presented. This problem-oriented format makes the book a superb reference resource for the working diagnostician and an ideal teaching tool for the resident or fellow. Coverage includes pediatric specimens and there is a section describing recognition of artifacts. Each case presentation is supported by several high-quality color photomicrographs with detailed explanations of each image, including images of the permanent sections and immunostains where applicable"-- Publisher's description.

Intraoperative frozen section interpretation is the base for treatment for the patient within the operating room. It requires immediate answer for the surgeon’s specific question and the subsequent consequences are frequently irreversible. The pathologist should be very familiar with the related differential diagnosis of the involved organ. Additionally, the pathologist needs to know many pitfalls and freezing artifacts in each organ and the clinical implications each diagnosis may result in. Frozen Section Library: Head and Neck will provide a convenient, user-friendly handbook to expedite use when performing intraoperative consultations on head and neck specimens. This book will be 5 X 8 and is estimated to be about 200 to 250 pages in toto with 100 to 150 color figures. An organ and clinical scenario based approach will be used in this book. This book will be divided into chapters based on the organs and anatomic locations. Within the chapter, a consistent format with the critical issues as a focus will be used including the frequently encountered clinical scenarios and the specific questions from the surgeons, frequent diagnostic considerations and their major diagnostic criteria with associated diagnostic pearls, artifacts and pitfalls and how to avoid them. Common and practical problems including reactive atypia versus carcinoma in salivary glands, resection margins in tongue and laryngectomy specimens, small blue cell tumors in the base of the skull, a primary lesion versus a metastatic squamous carcinoma in the neck, etc. will be illustrated with color pictures and accompanied legend. As a handbook for practicing pathologists, this book will be an indispensable aid to diagnosis and avoiding dangers in one of the most challenging situations that pathologists encounter. Rapid consideration of differential diagnoses and how to avoid traps caused by frozen section artifacts will be readily accessible to the users of this handbook. Tables and charts will provide guidance for differential diagnosis of various histological patterns. This book will be highly valuable to practicing surgical pathologists, both community and academic, and to pathology residents and fellows. The perspectives provided will also be valuable to head and neck surgeons and especially to surgery residents and head and neck surgery fellows who must answer questions about pathology and frozen section on their board examinations. This handbook will be easily portable by the individual but it is envisioned that many departments will want to also keep copies readily available in the frozen section laboratory.

Frozen section of Neuropathology-related cases is performed while the patient is undergoing surgery. Intraoperative consultation is used to help guide intraoperative management of the case and to ensure that adequate and appropriate tissue has been obtained for purposes of making an accurate final diagnosis. Frozen section diagnosis is often a highly demanding situation for the pathologist, who must render a diagnosis quickly and provide sound guidance and advice. In addition to the need for rapid recall of differential diagnoses, there are many pitfalls and artifacts that add to the risk of frozen section diagnosis that are not present with permanent sections of fully processed tissue that can be examined in a more leisurely fashion. Most standard pathology textbooks focus primarily on permanent section material and largely ignore the topic of frozen section. The purpose of this volume is to add to the Frozen Section Library series and provide a convenient, user friendly handbook to assist in the evaluation of central nervous system related frozen sections. It provides a useful reference, organized around differential diagnoses, primarily by location in the central nervous system. The text will be illustrated with color pictures and include tables as appropriate. This text provides a valuable tool for the practicing surgical pathologist both in community and in academic centers as well as pathology residents and fellows in training when confronted with Neuropathology frozen section.

The Frozen Section Library series provides concise, user-friendly, site specific handbooks that are well illustrated and highlight the pitfalls, artifacts and differential diagnosis issues that arise in the hurried frozen section scenario. Frozen Section Library: Lymph Nodes highlights the usefulness of techniques such as touch preparation cytology and fine needle aspiration (FNA) cytology, as well as FNA biopsy. This fascicle also suggests proper handling for subsequent ancillary studies, including flow cytometric, cytogenetic, and molecular studies. Special emphasis is given to the limitations of frozen section diagnosis in lymph node pathology. All chapters are written by experts in their fields and include the most up to date scientific information. This book serves as a very useful resource for physicians in the frozen section room and in intra-operative consultation situations dealing with, and interested in, this very complex field of diagnostic pathology. Frozen Section Library: Lymph Nodes is of great value to pathologists, residents, and fellows who diagnose pathologic processes involving lymph nodes. Cherie H. Dunphy, M.D. is Professor of Pathology and Laboratory Medicine, Executive Director of Hematopathology and Hematopathology Fellowship Department of Pathology and Laboratory Medicine University of North Carolina Chapel Hill, NC.