The Human Hypothalamus: Neuroendocrine Disorders, Volume 181 in the Handbook of Clinical Neurology series, provides comprehensive summaries of recent research on the brain and nervous system as they relate to clinical neurology. This volume summarizes the role of the hypothalamus in neuroendocrine disorders, identifying the mechanism of action, disorder etiology, and best practices for assessment and treatment. Disorders covered include pituitary hypothalamic disorders of development and growth, hypothalamic tumor related disorders, hypothalamic autoimmune disorders and infection, disorders of vasopressin, water and sodium homeostasis, eating disorders, and gonadotropic hormone regulation disorders. Discusses the importance of the hypothalamus in human growth and development Reviews hypothalamic related tumors, as well as pituitary, autoimmune, vasopressin and hormone regulation disorders Includes metabolic and eating disorders Identifies mechanisms of disease action and etiology Provides best practice information for assessment and treatment

Winner of the Third Neu-Whitrow Prize (2021) granted by the Commission on Bibliography and Documentation of IUHPS-DHST Additional background information This book provides bibliographic information, ownership records, a detailed worldwide census and a description of the handwritten annotations for all the surviving copies of the 1543 and 1555 editions of Vesalius’ De humani corporis fabrica. It also offers a groundbreaking historical analysis of how the Fabrica traveled across the globe, and how readers studied, annotated and critiqued its contents from 1543 to 2017. The Fabrica of Andreas Vesalius sheds a fresh light on the book’s vibrant reception history and documents how physicians, artists, theologians and collectors filled its pages with copious annotations. It also offers a novel interpretation of how an early anatomical textbook became one of the most coveted rare books for collectors in the 21st century.

During his tenure as the Regius Professor of Medicine at Oxford from 1905-1919, Sir William Osler amassed a considerable library on the history of medicine and science. A Canadian native, Osler had studied at McGill University and decided to leave his collection of 7,600 items to its Faculty of Medicine. A catalogue, the Bibliotheca Osleriana, was compiled - a labour of love that took ten years to complete and involved W.W. Francis, R.H. Hill, and Archibald Malloch. Osler himself laid down the broad outlines of the catalogue and wrote many of the annotations.

Handbook of Clinical Neurology: Volume 95 is the first of over 90 volumes of the handbook to be entirely devoted to the history of neurology. The book is a collection of historical materials from different neurology professionals. The book is divided into 6 sections and composed of 55 chapters organized around different aspects of the history of neurology. The first section presents the beginnings of neurology: ancient trepanation, its birth in Mesopotamia, ancient Egypt; the emergence of neurology in the biblical text and the Talmud; neurology in the Greco-Roman world and the period following Galen; neurological conditions in the European Middle Ages; and the development of neurology in the 17th and 18th centuries. The second section narrates the birth of localization theory; the beginning of neurology and histological applications, neuroanatomy, neurophysiology, surgical neurology and other anatomo-clinical methods. The third section covers further development of the discipline, including methods of neurological illustration and hospitals in neurology and neurosurgery. This section also narrates the history of child neurology, neurodisability and neuroendocrinology. It also features the application of molecular biology on clinical neurology. The fourth section describes the dysfunctions of the nervous system and their history. The fifth and last section covers the regional landmarks of neurology and the different treatments and recovery. The text is informative and useful for neuroscience or neurology professional, researchers, clinical practitioners, mental health experts, psychiatrists, and academic students and scholars in neurology. * A comprehensive accounting of historical developments and modern day advancements in the field of neurology * State-of-the-art information on topics including brain damage and dysfunctions of the nervous system * New treatments and recovery methods from redundancy to vicariation and neural transplantation, amongst others