This book provides a guiding thread between the distant fields of fluid mechanics and clinical cardiology. Well rooted in the science of fluid dynamics, it drives the reader across progressively more realistic scenarios up to the complexity of routine medical applications. Based on the author’s 25 years of collaborations with cardiologists, it helps engineers learn communicating with clinicians, yet maintaining the rigor of scientific disciplines. This book starts with a description of the fundamental elements of fluid dynamics in large blood vessels. This is achieved by introducing a rigorous physical background accompanied by examples applied to the circulation, and by presenting classic and recent results related to the application of fluid dynamics to the cardiovascular physiology. It then explores more advanced topics for a physics-based understanding of phenomena effectively encountered in clinical cardiology. It stands as an ideal learning resource for physicists and engineers working in cardiovascular fluid dynamics, industry engineers working on biomedical/cardiovascular technology, and students in bio-fluid dynamics. Written with a concise style, this textbook is accessible to a broad readership, including students, physical scientists and engineers, offering an entry point into this multi-disciplinary field. It includes key concepts exemplified by illustrations using cutting-edge imaging, references to modelling and measurement technologies, and includes unique original insights.

Biofliudics has gained in importance in recent years, forcing engineers to redefine mechanical engineering theories and apply them to biological functions. To date, no book has successfully done this. Biofliud Mechanics in Cardiovascular Systems is one of the first books to take an interdisciplinary approach to the subject. Written by a professor and researcher, this book will combine engineering principles with human biology to deliver a text specifically designed for biomedical engineering professionals and students.

Designed for senior undergraduate or first-year graduate students in biomedical engineering, Biofluid Mechanics: The Human Circulation, Second Edition teaches students how fluid mechanics is applied to the study of the human circulatory system. Reflecting changes in the field since the publication of its predecessor, this second edition has been ex

Both broad and deep in coverage, Rubenstein shows that fluid mechanics principles can be applied not only to blood circulation, but also to air flow through the lungs, joint lubrication, intraocular fluid movement and renal transport. Each section initiates discussion with governing equations, derives the state equations and then shows examples of their usage. Clinical applications, extensive worked examples, and numerous end of chapter problems clearly show the applications of fluid mechanics to biomedical engineering situations. A section on experimental techniques provides a springboard for future research efforts in the subject area. Uses language and math that is appropriate and conducive for undergraduate learning, containing many worked examples and end of chapter problems All engineering concepts and equations are developed within a biological context Covers topics in the traditional biofluids curriculum, as well as addressing other systems in the body that can be described by biofluid mechanics principles, such as air flow through the lungs, joint lubrication, intraocular fluid movement, and renal transport Clinical applications are discussed throughout the book, providing practical applications for the concepts discussed.

The book presents the state of the art in the interdisciplinary field of fluid mechanics applied to cardiovascular modelling. It is neither a monograph nor a collection of research papers, rather an extended review in the field. It is arranged in 4 scientific chapters each presenting thoroughly the approach of a leading research team; two additional chapters prepared by biomedical scientists present the topic by the applied perspective. A unique feature is a substantial (approx. one fourth of the book) medical introductory part, written by clinical researchers for scientific readers, that would require a large effort to be collected otherwise.

Biofluid mechanics is the study of a certain class of biological problems from the viewpoint of fluid mechanics. Though biofluid mechanics does not involve any new development of the general principles of fluid mechanics, it does involve some new applications of its methods. Complex movements of fluids in the biological system demand for an analysis achievable only with professional fluid mechanics skills, and this volume aims to equip readers with the knowledge needed.This second edition is an enlarged version of the book published in 1992. While retaining the general plan of the first edition, this new edition presents an engineering analysis of the cardiovascular system relevant to the treatment of cardiovascular diseases and combines engineering principles. Included in the material of this volume are: the emerging interdisciplinary field of tissue engineering, which deals with the principles of engineering and life sciences toward the development of biological substitutes that restore, maintain and improve tissue function, and cellular and molecular bioengineering, which involves the mechanical, electrical and chemical processes of the human cell and tries to explain how cellular behaviour arises from molecular-level interactions.The added material in this edition is specifically designed for biomedical engineering professionals and students, and looks at the important applications of biofluid mechanics from an engineering perspective.

The objective of this book is to illustrate in specific detail how cardiovascular mechanics stands as a common pillar supporting such different clinical successes as drugs for high blood pressure, prosthetic heart valves and coronary artery bypass grafting, among others. This information is conveyed through a comprehensive treatment of the overarching principles and theories that are behind mechanobiological processes, aortic and arterial mechanics, atherosclerosis, blood and microcirculation, hear valve mechanics, as well as medical devices and drugs. Examines all major theoretical and practical aspects of mechanical forces related to the cardiovascular system. Discusses a unique coverage of mechanical changes related to an aging cardiovascular system. Provides an overview of experimental methods in cardiovascular mechanics. Written by world-class researchers from Canada, the US and EU. Extensive references are provided at the end of each chapter to enhance further study. Michel R. Labrosse is the founder of the Cardiovascular Mechanics Laboratory at the University of Ottawa, where he is a full professor within the Department of Mechanical Engineering. He has been an active researcher in academia along with being heavily associated with the University of Ottawa Heart Institute. He has authored or co-authored over 90 refereed communications, and supervised or co-supervised over 40 graduate students and post-docs.