When a new influenza virus emerges that is able to be transmitted between humans, it spreads globally as a pandemic, often with high mortality. Enormous social disruption and substantial economic cost can result. The 1918 Spanish influenza pandemic was undoubtedly the most devastating influenza pandemic to date, and it has been Dr Robert Websters lifes work to figure out how and why. In so doing he has made a remarkable contribution to our understanding of the evolution of influenza viruses and how to control them. A century on, Flu Hunter is a gripping account of the tenacious scientific detective work involved in revealing the secrets of this killer virus. Dubbed Flu Hunter by Smithsonian Magazine in 2006, Dr Webster began his research in the early 1960s with the insight that the natural ecology of most influenza viruses is among wild aquatic birds. Painstaking tracking and testing of thousands of birds eventually led him and the other scientists involved to establish a link between these bird virus reservoirs and human influenza pandemics. Some of this fascinating scientific work involved exhuming bodies of Spanish flu victims from the Arctic permafrost in a search for tissue samples containing genetic material from the virus. Could a global influenza pandemic occur again? Websters warning is clear: "... it is not only possible, it is just a matter of when."

In 1918 the Spanish flu epidemic swept the world and killed an estimated 20 to 40 million people in just one year, more than the number that died during the four years of the First World War. To this day medical science has been at a loss to explain the Spanish flu's origin. Most virologists are convinced that sooner or later a similarly deadly flu virus will return with a vengeance; thus anything we can learn from the 1918 flu may save lives in a new epidemic. Responding to sustained interest in this medical mystery, Hunting the 1918 Flu presents a detailed account of Kirsty Duncan's experiences as she organized an international, multi-discipline scientific expedition to exhume the bodies of a group of Norwegian miners buried in Svalbard, all victims of the flu virus. Constant throughout is her determination to honour the Norwegian laws and the Svalbard customs that treat the dead and the living with respect - especially when a live virus, if unearthed, could kill millions. Another theme of the book is the author's growing love for Svalbard and its people. Duncan's narrative describes a large-scale medical project to uncover genetic material from the Spanish flu; it also reveals the turbulent politics of a group moving towards a goal where the egos were as strong as the stakes were high. The author, herself a medical geographer, is very frank about her bruising emotional, financial, and professional experiences on the 'dark side of science.' Duncan raises questions not only about public health, epidemiology, the ethics of science, and the rights of subjects, but also about the role of age, gender, and privilege in science. While her search for the virus has shown promising results, it has also revealed the dangers of science itself being subsumed in the rush for personal acclaim.

On the 100th anniversary of the pandemic of 1918, Jeremy Brown, veteran ER doctor and Director of Emergency Care Research at the National Institutes of Health, explores the troubling and complex history of the flu virus. He breaks down the current dialogue about the disease, explaining the controversy over vaccinations, antiviral drugs, and the federal government's role in preparing for pandemic outbreaks. Influenza is an enlightening and unnerving look at a deadly virus that has been around longer than people and may be for many more years before we are able to conquer it for good.

After experiencing the SARS outbreak in 2003, Hong Kong, Singapore, and Taiwan all invested in various techniques to mitigate future pandemics involving myriad cross-species interactions between humans and birds. In some locations microbiologists allied with veterinarians and birdwatchers to follow the mutations of flu viruses in birds and humans and create preparedness strategies, while in others, public health officials worked toward preventing pandemics by killing thousands of birds. In Avian Reservoirs Frédéric Keck offers a comparative analysis of these responses, tracing how the anticipation of bird flu pandemics has changed relations between birds and humans in China. Drawing on anthropological theory and ethnographic fieldwork, Keck demonstrates that varied strategies dealing with the threat of pandemics—stockpiling vaccines and samples in Taiwan, simulating pandemics in Singapore, and monitoring viruses and disease vectors in Hong Kong—reflect local geopolitical relations to mainland China. In outlining how interactions among pathogens, birds, and humans shape the way people imagine future pandemics, Keck illuminates how interspecies relations are crucial for protecting against such threats.

Veteran journalist Gina Kolata's Flu: The Story of the Great Influenza Pandemic of 1918 and the Search for the Virus That Caused It presents a fascinating look at true story of the world's deadliest disease. In 1918, the Great Flu Epidemic felled the young and healthy virtually overnight. An estimated forty million people died as the epidemic raged. Children were left orphaned and families were devastated. As many American soldiers were killed by the 1918 flu as were killed in battle during World War I. And no area of the globe was safe. Eskimos living in remote outposts in the frozen tundra were sickened and killed by the flu in such numbers that entire villages were wiped out. Scientists have recently rediscovered shards of the flu virus frozen in Alaska and preserved in scraps of tissue in a government warehouse. Gina Kolata, an acclaimed reporter for The New York Times, unravels the mystery of this lethal virus with the high drama of a great adventure story. Delving into the history of the flu and previous epidemics, detailing the science and the latest understanding of this mortal disease, Kolata addresses the prospects for a great epidemic recurring, and, most important, what can be done to prevent it.

In 1976, a small group of soldiers at Fort Dix were infected with a swine flu virus that was deemed similar to the virus responsible for the great 1918-19 world-wide flu pandemic. The U.S. government initiated an unprecedented effort to immunize every American against the disease. While a qualified success in terms of numbers reached-more than 40 million Americans received the vaccine-the disease never reappeared. The program was marked by controversy, delay, administrative troubles, legal complications, unforeseen side effects and a progressive loss of credibility for public health authorities. In the waning days of the flu season, the incoming Secretary of what was then the Department of Health, Education and Welfare, Joseph Califano, asked Richard Neustadt and Harvey Fineberg to examine what happened and to extract lessons to help cope with similar situations in the future.

In 1918, the Spanish flu killed up to 40 million people across the planet. From the remotest villages in Arctic climates to crowded U.S. cities to the battlefields of Europe, there were plague houses in which whole families lay sick or dead. In Madras, train services stopped running, as one-third of its workforce fell ill. In Calcutta, the postal service and the legal system ground to a halt. And in the United States, it killed more Americans than all the wars fought in the twentieth century put together. The disease did not discriminate. It took whom it pleased -- rich or poor, distinguished or humble, hungry or well nourished, healthy or infirm. It was a flu unlike any that the world had encountered before or that has come along since.