The enormous recent success of molecular developmental biology has yielded a vast amount of new information on the details of development. So much so that we risk losing sight of the underlying principles that apply to all development. To cut through this thicket, John Tyler Bonner ponders a moment in evolution when development was at its most basic--the moment when signaling between cells began. Although multicellularity arose numerous times, most of those events happened many millions of years ago. Many of the details of development that we see today, even in simple organisms, accrued over a long evolutionary timeline, and the initial events are obscured. The relatively uncomplicated and easy-to-grow cellular slime molds offer a unique opportunity to analyze development at a primitive stage and perhaps gain insight into how early multicellular development might have started. Through slime molds, Bonner seeks a picture of the first elements of communication between cells. He asks what we have learned by looking at their developmental biology, including recent advances in our molecular understanding of the process. He then asks what is the most elementary way that polarity and pattern formation can be achieved. To find the answer, he uses models, including mathematical ones, to generate insights into how cell-to-cell cooperation might have originated. Students and scholars in the blossoming field of the evolution of development, as well as evolutionary biologists generally, will be interested in what Bonner has to say about the origins of multicellular development--and thus of the astounding biological complexity we now observe--and how best to study it.

Kicking of a new four-book series by an Air Force Reserve captain and UFO authority, this title explores the future evolution of man and machine, in which the search for intelligent life becomes the catalyst of man's dreams--and the stars, man's destination. Original.

First demonstrated in 1928, color television remained little more than a novelty for decades as the industry struggled with the considerable technical, regulatory, commercial, and cultural complications posed by the medium. Only fully adopted by all three networks in the 1960s, color television was imagined as a new way of seeing that was distinct from both monochrome television and other forms of color media. It also inspired compelling popular, scientific, and industry conversations about the use and meaning of color and its effects on emotions, vision, and desire. In Bright Signals Susan Murray traces these wide-ranging debates within and beyond the television industry, positioning the story of color television, which was replete with false starts, failure, and ingenuity, as central to the broader history of twentieth-century visual culture. In so doing, she shows how color television disrupted and reframed the very idea of television while it simultaneously revealed the tensions about technology's relationship to consumerism, human sight, and the natural world.

A widely celebrated novelist gives us a generous collection of exhilarating short stories, proving that he is a master of this genre as well. Once again, "he reminds us," wrote The Miami Herald, "that great writing is a timeless art." After the stunning historical novels The Clearing and The Missing, Tim Gautreaux now ranges freely through contemporary life with twelve new stories and eight from previous collections. Most are set in his beloved Louisiana, many hard by or on the Mississippi River, others in North Carolina and even in midwinter Minnesota. But generally it's heat, humidity, and bugs that beset his people as they wrestle with affairs of the heart, matters of faith, and the pros and cons of tight-knit communities--a remarkable cast of characters, primarily of the working class, proud and knowledgeable about the natural or mechanical world, their lives marked by a prized stereo or a magical sewing machine retrieved from a locked safe, boats and card games and casinos, grandparents and grandchildren and those in between, their experiences leading them to the ridiculous or the scarifying or the sublime; most of them striving for what's right and good, others tearing off in the opposite direction.

Joel Rothschild and his friend Albert, both HIV positive, made a pact: whoever died first would attempt to "signal" the other from beyond. Joel wasn't sure he believed in psychic abilities, but from the day Albert died he began receiving messages. One message led Joel to a note Albert had left for him before he died. Another message told Joel to hang in there when he became sick, that he would get well - and he did.Albert's messages have changed not only Joel's life but the lives of many others who have been helped by messages Joel has delivered to them. Their stories and Joel's psychic awakening - a transformation from cynic to believer - are both amazing and reassuring.

In this book the author, an investigative journalist, traces the social history of marijuana from its origins to its emergence in the 1960s as a defining force in an ongoing culture war. He describes how the illicit marijuana subculture overcame government opposition and morphed into a multibillion-dollar industry. In 1996, Californians voted to legalize marijuana for medicinal purposes. Similar laws have followed in several other states, but not without antagonistic responses from federal, state, and local law enforcement. The author draws attention to underreported scientific breakthroughs that are reshaping the therapeutic landscape: medical researchers have developed promising treatments for cancer, heart disease, Alzheimer's, diabetes, chronic pain, and many other conditions that are beyond the reach of conventional cures. This book is an examination of the medical, recreational, scientific, and economic dimensions of the world's most controversial plant.