International Federation for Information Processing The IFIP series publishes state-of-the-art results in the sciences and technologies of information and communication. The scope of the series includes: foundations of computer science; software theory and practice; education; computer applications in technology; communication systems; systems modeling and optimization; information systems; computers and society; computer systems technology; security and protection in information processing systems; artificial intelligence; and human-computer interaction. Proceedings and post-proceedings of refereed international conferences in computer science and interdisciplinary fields are featured. These results often precede journal publication and represent the most current research. The principal aim of the IFIP series is to encourage education and the dissemination and exchange of information about all aspects of computing. For more information about the 300 other books in the IFIP series, please visit www.springer.com. For more information about IFIP, please visit www.ifip.org.

Samson Abramsky’s wide-ranging contributions to logical and structural aspects of Computer Science have had a major influence on the field. This book is a rich collection of papers, inspired by and extending Abramsky’s work. It contains both survey material and new results, organised around six major themes: domains and duality, game semantics, contextuality and quantum computation, comonads and descriptive complexity, categorical and logical semantics, and probabilistic computation. These relate to different stages and aspects of Abramsky’s work, reflecting its exceptionally broad scope and his ability to illuminate and unify diverse topics. Chapters in the volume include a review of his entire body of work, spanning from philosophical aspects to logic, programming language theory, quantum theory, economics and psychology, and relating it to a theory of unification of sciences using dual adjunctions. The section on game semantics shows how Abramsky’s work has led to a powerful new paradigm for the semantics of computation. The work on contextuality and categorical quantum mechanics has been highly influential, and provides the foundation for increasingly widely used methods in quantum computing. The work on comonads and descriptive complexity is building bridges between currently disjoint research areas in computer science, relating Structure to Power. The volume also includes a scientific autobiography, and an overview of the contributions. The outstanding set of contributors to this volume, including both senior and early career academics, serve as testament to Samson Abramsky’s enduring influence. It will provide an invaluable and unique resource for both students and established researchers.

This book constitutes the refereed proceedings of the 34th International Symposium on Mathematical Foundations of Computer Science, MFCS 2009, held in Novy Smokovec, High Tatras, Slovakia, in August 2009. The 56 revised full papers presented together with 7 invited lectures were carefully reviewed and selected from 148 submissions. All current aspects in theoretical computer science and its mathematical foundations are addressed, including algorithmic game theory, algorithmic tearning theory, algorithms and data structures, automata, grammars and formal languages, bioinformatics, complexity, computational geometry, computer-assisted reasoning, concurrency theory, cryptography and security, databases and knowledge-based systems, formal specifications and program development, foundations of computing, logic in computer science, mobile computing, models of computation, networks, parallel and distributed computing, quantum computing, semantics and verification of programs, theoretical issues in artificial intelligence.

This book constitutes the refereed proceedings of the 8th International Symposium on Software Composition, SC 2009, held in Zurich, Switzerland, in July 2009. The workshop has been organized as an event co-located with the TOOLS Europe 2009 conference. The 10 revised full papers presented together with 2 invited lectures were carefully reviewed and selected from 34 submissions. The papers reflect current research in software composition to foster developing of composition models and techniques by using aspect- and service-oriented programming, specification of component contracts and protocols, methods of correct components composition, as well as verification, validation and testing techniques - even in pervasive computing environments and for the Web.

Induction is a pervasive tool in computer science and mathematics for defining objects and reasoning on them. Coinduction is the dual of induction and as such it brings in quite different tools. Today, it is widely used in computer science, but also in other fields, including artificial intelligence, cognitive science, mathematics, modal logics, philosophy and physics. The best known instance of coinduction is bisimulation, mainly employed to define and prove equalities among potentially infinite objects: processes, streams, non-well-founded sets, etc. This book presents bisimulation and coinduction: the fundamental concepts and techniques and the duality with induction. Each chapter contains exercises and selected solutions, enabling students to connect theory with practice. A special emphasis is placed on bisimulation as a behavioural equivalence for processes. Thus the book serves as an introduction to models for expressing processes (such as process calculi) and to the associated techniques of operational and algebraic analysis.

This book constitutes the proceedings of the 19th International Conference on Tools and Algorithms for the Construction and Analysis of Systems, TACAS 2013, held in Rome, Italy, in March 2013. The 42 papers presented in this volume were carefully reviewed and selected from 172 submissions. They are organized in topical sections named: Markov chains; termination; SAT/SMT; games and synthesis; process algebra; pushdown; runtime verification and model checking; concurrency; learning and abduction; timed automata; security and access control; frontiers (graphics and quantum); functional programs and types; tool demonstrations; explicit-state model checking; Büchi automata; and competition on software verification.

This second edition volume expands on the previous edition with discussions of the latest advancements and methods used by scientists to study systems biology. The chapters in this book are organized into four parts. Part One looks at models in systems biology and parameters identification such as short peptide analysis, metastasis models, and metabolomics. Part Two covers computational methods in the study of organisms, and cancer non-linear dynamics. Part Three discusses critical transition states across Waddington’s like landscapes such as understanding cell differentiation through single-cell approaches and modeling mammary organogenesis from biological first principles. Part Four talks about specific fields of investigation including inborn errors of metabolism, system biology approach in epithelial-mesenchymal transition, and an approach to understanding how COVID-19 spreads in the population. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. Cutting-edge and comprehensive, Systems Biology, Second Edition is a valuable tool for any researcher looking to learn more about this important and developing field.