How new biomedical technologies—from prenatal testing to gene-editing techniques—require us to imagine who counts as human and what it means to belong. From next-generation prenatal tests, to virtual children, to the genome-editing tool CRISPR-Cas9, new biotechnologies grant us unprecedented power to predict and shape future people. That power implies a question about belonging: which people, which variations, will we welcome? How will we square new biotech advances with the real but fragile gains for people with disabilities—especially when their voices are all but absent from the conversation? This book explores that conversation, the troubled territory where biotechnology and disability meet. In it, George Estreich—an award-winning poet and memoirist, and the father of a young woman with Down syndrome—delves into popular representations of cutting-edge biotech: websites advertising next-generation prenatal tests, feature articles on “three-parent IVF,” a scientist's memoir of constructing a semisynthetic cell, and more. As Estreich shows, each new application of biotechnology is accompanied by a persuasive story, one that minimizes downsides and promises enormous benefits. In this story, people with disabilities are both invisible and essential: a key promise of new technologies is that disability will be repaired or prevented. In chapters that blend personal narrative and scholarship, Estreich restores disability to our narratives of technology. He also considers broader themes: the place of people with disabilities in a world built for the able; the echoes of eugenic history in the genomic present; and the equation of intellect and human value. Examining the stories we tell ourselves, the fables already creating our futures, Estreich argues that, given biotech that can select and shape who we are, we need to imagine, as broadly as possible, what it means to belong.

How new biomedical technologies—from prenatal testing to gene-editing techniques—require us to imagine who counts as human and what it means to belong. From next-generation prenatal tests, to virtual children, to the genome-editing tool CRISPR-Cas9, new biotechnologies grant us unprecedented power to predict and shape future people. That power implies a question about belonging: which people, which variations, will we welcome? How will we square new biotech advances with the real but fragile gains for people with disabilities—especially when their voices are all but absent from the conversation? This book explores that conversation, the troubled territory where biotechnology and disability meet. In it, George Estreich—an award-winning poet and memoirist, and the father of a young woman with Down syndrome—delves into popular representations of cutting-edge biotech: websites advertising next-generation prenatal tests, feature articles on “three-parent IVF,” a scientist's memoir of constructing a semisynthetic cell, and more. As Estreich shows, each new application of biotechnology is accompanied by a persuasive story, one that minimizes downsides and promises enormous benefits. In this story, people with disabilities are both invisible and essential: a key promise of new technologies is that disability will be repaired or prevented. In chapters that blend personal narrative and scholarship, Estreich restores disability to our narratives of technology. He also considers broader themes: the place of people with disabilities in a world built for the able; the echoes of eugenic history in the genomic present; and the equation of intellect and human value. Examining the stories we tell ourselves, the fables already creating our futures, Estreich argues that, given biotech that can select and shape who we are, we need to imagine, as broadly as possible, what it means to belong.

An estimated 80 million people live with a neurodegenerative disease. That number is expected to increase rapidly as populations age, lifespans increase, and exposure to toxins rises. Despite decades of research and billions in funding, there are no medications that can slow, much less stop, the progress of these diseases. This is because diseases such as Parkinson's and Alzheimer's do not exist in biology. Yet, hundreds of clinical trials around the world are examining the potential of single therapies in thousands of people sharing one of these labels. Compounding the problem, these therapies were developed on evidence from models that do not come close to capturing the complexity of these diseases in the affected humans. These practices must end. Brain Fables is a call to refocus on understanding living and aging to create the personalized treatments each affected individual desperately needs.

One of the world's leading investment researchers runs the numbers on some of today's most widely touted strategies, objectively answering the questions brokers cannot answer and presents exactly what works and what doesn't.

Despite originating more than two-and-a-half thousand years ago, Aesop's Fables are still passed on from parent to child, and are embedded in our collective consciousness. The morals we have learned from these tales continue to inform our judgements, but have the stories also informed how we regard their animal protagonists? If so, is there any truth behind the stereotypes? Are wolves deceptive villains? Are crows insightful geniuses? And could a tortoise really beat a hare in a race? In Aesop's Animals, zoologist Jo Wimpenny turns a critical eye to the fables to discover whether there is any scientific truth to Aesop's portrayal of the animal kingdom. She brings the tales into the twenty-first century, introducing the latest findings on some of the most fascinating branches of ethological research – the study of why animals do the things they do. In each chapter she interrogates a classic fable and a different topic – future planning, tool use, self-recognition, cooperation and deception – concluding with a verdict on the veracity of each fable's portrayal from a scientific perspective. By sifting fact from fiction in one of the most beloved texts of our culture, Aesop's Animals explores and challenges our preconceived notions about animals, the way they behave, and the roles we both play in our shared world.

The Aesop's Fable Paradigm is a collection of essays that explore the cutting-edge intersection of Folklore and Science. From moralizing fables to fantastic folktales, humans have been telling stories about animals—animals who can talk, feel, think, and make moral judgments just as we do—for a very long time. In contrast, scientific studies of the mental lives of animals have professed to be investigating the nature of animal minds slowly, cautiously, objectively, with no room for fanciful tales, fables, or myths. But recently, these folkloric and scientific traditions have merged in an unexpected and shocking way: scientists have attempted to prove that at least some animal fables are actually true. These interdisciplinary chapters examine how science has targeted the well-known Aesop's fable "The Crow and the Pitcher" as their starting point. They explore the ever-growing set of experimental studies which purport to prove that crows possess an understanding of higher-order concepts like weight, mass, and even Archimedes' insight about the physics of water displacement. The Aesop's Fable Paradigm explores how these scientific studies are doomed to accomplish little more than to mirror anthropomorphic representations of animals in human folklore and reveal that the problem of folkloric projection extends far beyond the "Aesop's Fable Paradigm" into every nook and cranny of research on animal cognition.

Fables and Spells is a vibrant selection of visionary works, both previously published and brand new. Included here is brown’s most beloved story, “The River,” as well as the two sequel tales of her Water Trio. The remaining sixty-seven pieces explore moments of beauty, conflict, and transformation that also weave deep, radical lessons. With narrative “fables” of speculative fiction and “spells” that play with the lines between poetry, instruction, song, and chant, Fables and Spells demonstrates how good writing can engage the present while providing expansive visions of the possible worlds humans can build. adrienne maree brown’s previous work includes Octavia’s Brood, Emergent Strategy, the New York Times best-selling Pleasure Activism, We Will Not Cancel Us, Holding Change, and Grievers. brown grows transformative ideas in public through her writing and art; she is a poet changing the world. She is the writer-in-residence at Emergent Strategy Ideation Institute.