Extracorporeal photopheresis (ECP) is the first FDA approved cellular photoimmunotherapy for cancer, namely cutaneous T-cell lymphoma, and has demonstrated efficacy in various diseases that have a suspected involvement of pathogenic T-cells including prevention and treatment of acute and chronic graft-versus-host disease, organ transplant rejection, selected autoimmune diseases and Sezary syndrome. In ECP, patient’s blood mononuclear cells are collected, exposed to ultraviolet light in the presence of extracorporeally administered liquid 8-methoxypsoralen and reinfused. Besides its considerable efficacy ECP has an exceptional safety profile, does not cause general immunosuppression and thus, does not increase risk of infectious complications and relapse of malignant disease. Exciting preclinical data and clinical observations provide insight into the mechanisms of action of ECP and support its immunomodulatory role. This book will provide an overview on the historical development of ECP, technical aspects for its use in various patient populations including children and adults, novel research findings both in preclinical models and in various patient cohorts and will stimulate further research in organ, tissue and cell transplantation and autoimmune disorders.

Covering the entire array of photodermatological topics necessary to stand at the head of this burgeoning discipline, this source contains expertly written chapters that offer recommendations and guidelines from opinion-forming international authorities. Reviewing the entire range of photodermatoses, as well as the management, treatment, i

This second edition of the renowned "The European Handbook of Dermatological Treatments" has been fully update. It now covers the latest developments of drugs, methods and treatments in dermatological practice. The handbook features the easy-to-read and well-proven format of the first edition, making it ideal for physicians who want comprehensive information at a glance. The three main sections listed alphabetically define the different diseases, the drugs available and the various methods of treatment used in dermatological practice. Each chapter begins with a brief section of the aetiology and pathogenesis of the skin disease, and leads into the description of the clinical characteristics, the diagnosis and the differential diagnosis. Followed by a detailed discussion on treatment methods, alternative methods are covered as well. Each section ends with a reference list for further reading. The handbook is a very comprehensive and practical guide and should not be missed by those treating patients with skin diseases.

Safely and effectively treat a full range of skin disorders with Comprehensive Dermatologic Drug Therapy, 3rd Edition! This trusted dermatology reference provides concise, complete, up-to-date guidance on today's full spectrum of topical, intralesional, and systemic drugs. Dr. Steven E. Wolverton and a team of leading international experts clearly explain what drugs to use, when to use them, and what to watch out for. Prescribe with confidence thanks to quick-access summaries of indications/contraindications, dosage guidelines, drug interactions, drug monitoring guidelines, adverse effects, and treatment protocols. Assess your knowledge and prepare for certification or recertification with more than 800 review questions and answers throughout the book. Contain costs and meet patient expectations with purchase information provided for major drugs. Quickly evaluate drug options for each disease discussed using a highly detailed, disease-specific index. Discover the best uses for new biologic therapeutics such as ustekinumab and rituximab, as well as newly improved TNF inhibitors. Offer your patients the very latest in cosmetic procedures, including chemical peels, intradermal fillers, and botulinum toxin. Use the safest and most effective drugs possible with new chapters on irritants and allergens in topical therapeutic agents, plus a new, separate chapter on mycophenolate mofetil. Review drugs recently taken off the market by the FDA, and use that knowledge to improve your current dermatologic drug therapy. Access the complete contents online at www.expertconsult.com and perform rapid searches for drug indications, interactions, monitoring guidelines, and much more.

This Research Topic in Frontiers in Medicine offers a concise overview of the latest knowledge in the field of Photomedicine on therapeutic and preventive modalities, and UV pathogenesis of skin cancer. Photomedicine has revolutionized the treatment of inflammatory and neoplastic skin diseases over the last century since Niels Ryberg Finsen was awarded in 1903 the Nobel Prize “in recognition of his contribution to the treatment of diseases, especially lupus vulgaris, with concentrated light radiation, whereby he has opened a new avenue for medical science”. From then on, the field has moved on in leaps and bounds to expand phototreatment to many inflammatory as well as neoplastic skin diseases. With this Research Topic we aim to promote the field by giving the latest insights into Photomedicine’s therapeutic modalities and molecular mechanisms in treatment of diseases of the skin and beyond, as well as prevention from photodermatoses and carcinogenesis, as the dark sites of light. By engaging clinicians and scientists we intend to advance basic, clinical and translational research in the field of Photomedicine with its numerous facets.

This book is the most up-to-date publication on photodiagnostic and phototherapeutic methods used in dermatology. Edited by international experts in the field, it offers comprehensive information on every aspect of Photodiagnostics and Phototherapy. The book focuses on the clinical aspects: detailed descriptions of photo- and photochemotherapy for the treatment of selected diseases as well as standardized test protocols for photodermatoses and for the diagnosis of skin tumors are presented. The clinically oriented chapters are supplemented by practical guidelines for phototherapy and information about basic principles of photobiology.