This unique sourcebook describes the research methods used to study human brain function and brain-behavior relationships. These range from relatively simple approaches, such as dichotic listening and tachistoscopic presentation, to computerized techniques such as cerebral blood flow measurements. The description of each method covers the underlying theory, variations on the basic paradigm, dependent measures, reliability and validity, and the equipment required. The authors also critically review research with normal and clinical populations. Because of the rapid expansion of the field of human neuropsychology--and accompanying technological advances--this volume will be valued as much by experienced researchers as by newcomers seeking an introduction to the variety of available procedures.

The present volume aims at presenting a selection of new methods and techniques that may have value for clinical neuropsychology. There is an increasing interest among clinical neuropsychologists regarding new developments in cognitive neuroscience and experimental psychology. This book presents an updated view of recent methodological developments in experimental psychology and clinical neuroscience.

Modern neuroscience research is inherently multidisciplinary, with a wide variety of cutting edge new techniques to explore multiple levels of investigation. This Third Edition of Guide to Research Techniques in Neuroscience provides a comprehensive overview of classical and cutting edge methods including their utility, limitations, and how data are presented in the literature. This book can be used as an introduction to neuroscience techniques for anyone new to the field or as a reference for any neuroscientist while reading papers or attending talks. - Nearly 200 updated full-color illustrations to clearly convey the theory and practice of neuroscience methods - Expands on techniques from previous editions and covers many new techniques including in vivo calcium imaging, fiber photometry, RNA-Seq, brain spheroids, CRISPR-Cas9 genome editing, and more - Clear, straightforward explanations of each technique for anyone new to the field - A broad scope of methods, from noninvasive brain imaging in human subjects, to electrophysiology in animal models, to recombinant DNA technology in test tubes, to transfection of neurons in cell culture - Detailed recommendations on where to find protocols and other resources for specific techniques - "Walk-through" boxes that guide readers through experiments step-by-step

The domain of neuroscience has had one of the most explosive growths in recent decades: within this development there has been a remarkable and renewed interest in the study of the relations between behaviour and the central nervous system. Part of this new attention is connected with the contribution of new technologies (PET, fMRI) permitting more precise mapping of neural structures responsible for cognitive functions and the development of new theoretical models of mental activities. The diffusion of new pathologies (for example the pattern of cognitive impairment associated with AIDS) has further enlarged the field of clinical neuropsychology. Finally there has been an expanding clinical interest in the understanding and management of age-related cognitive changes. This volume is the translated and updated version of the second edition of Manuale di Neuropsicologia (Zanichelli, 1996), by the same authors, and it reflects the current status of the art. It is intended to blend clinical and theoretical aspects of neuropsychology. The first part discusses the instrumental and clinical methods of investigation in neuropsychology, together with their development. A long section is dedicated to the language and memory disorders. The impairment of non-verbal cognitve functions, such as the disorders of space orientation, of of visuo-perceptive abilities, and of the emotions and attention, are extensively discussed. The pattern of degenerative dementias is thorougly described, as e is thoroughly described, as well as a number of new topics, such as a neuropsychological approach to consciousness. Finally, perspectives for treatment of some cognitive disorders are outlined.

As you read this, you are probably unaware of how your left foot feels in your shoe. Although your brain was receiving sensory input from this foot, you were not aware of your foot because you were reading and not attending to it. However, this discussion led you to move your attention to your left foot and to become aware of it. When I was a medical student, I saw a patient who was unaware of both the left side of his body and the left side of his environment. Unlike people in normal health, who when instructed can become aware of the left side of the body; this patient could not be made aware of his left arm or the left side of his environment. The patient's defect was so profound that despite being hungry he was unaware of food on the left side of his tray and did not recognize that his left arm belonged to him. This left-sided body and spatial unawareness could not be accounted for by a primary sensory defect. Although I knew that this man suffered from a large right-hemisphere stroke, I did not know the brain mechanisms that accounted for this profound example of unawareness. It was not until I had almost completed my neurology training in 1969 that I was able to return to this problem. At that time, most neuropsychological research was directed at understanding the language disorders associated with brain disease.

This volume is the translated and updated version of the second edition of Manuale di Neuropsicologia (Zanichelli, 1996), by the same authors, and it reflects the current status of the art.

The present volume aims at presenting a selection of new methods and techniques that may have value for clinical neuropsychology. There is an increasing interest among clinical neuropsychologists regarding new developments in cognitive neuroscience and experimental psychology. This book presents an updated view of recent methodological developments in experimental psychology and clinical neuroscience.