The order Rodentia is the most abundant and successful group of mammals, and it has been a focal point of attention for compar ative and evolutionary biologists for many years. In addition, rodents are the most commonly used experimental mammals for bio medical research, and they have played a central role in investi gations of the genetic and molecular mechanisms of speciation in mammals. During recent decades, a tremendous amount of new data from various aspects of the biology of living and fossil rodents has been accumulated by specialists from different disciplines, ranging from molecular biology to paleontology. Paradoxically, our understanding of the possible evolutionary relationships among different rodent families, as well as the possible affinities of rodents with other eutherian mammals, has not kept pace with this information "explosion. " This abundance of new biological data has not been incorporated into a broad synthesis of rodent phylo geny, in part because of the difficulty for any single student of rodent evolution to evaluate the phylogenetic significance of new findings from such diverse disciplines as paleontology, embryology, comparative anatomy, molecular biology, and cytogenetics. The origin and subsequent radiation of the order Rodentia were based primarily on the acquisition of a key character complex: specializations of the incisors, cheek teeth, and associated mus culoskeletal features of the jaws and skull for gnawing and chewing.

The widespread use of mouse models in developmental, behavioural and genetic studies has sparked wider interest in rodent biology as a whole. This book brings together the latest research on rodents to better understand the evolution of both living and extinct members of this fascinating group. Topics analysed include the role of molecular techniques in the determination of robust phylogenetic frameworks; how geometric morphometric methods help quantify and analyse variation in shape; and the role of developmental biology in elucidating the origins of skeletal elements and the teeth. The editors unite these disciplines to present the current state of knowledge in rodent biology, whilst setting the landscape for future research. This book highlights interdisciplinary links across palaeontology, developmental biology, functional morphology, phylogenetics and biomechanics, making it a valuable resource for evolutionary biologists in all fields.

A valuable resource for the latest research on rodents, highlighting links across palaeontology, developmental biology, functional morphology, phylogenetics and biomechanics.

"The book before you...carries the urgent warning that we are rapidly altering and destroying the environments that have fostered the diversity of life forms for more than a billion years." With those words, Edward O. Wilson opened the landmark volume Biodiversity (National Academy Press, 1988). Despite this and other such alarms, species continue to vanish at a rapid rate, taking with them their genetic legacy and potential benefits. Many disappear before they can even be identified. Biodiversity II is a renewed call for urgency. This volume updates readers on how much we already know and how much remains to be identified scientifically. It explores new strategies for quantifying, understanding, and protecting biodiversity, including: New approaches to the integration of electronic data, including a proposal for a U.S. National Biodiversity Information Center. Application of techniques developed in the human genome project to species identification and classification. The Gap Analysis Program of the National Biological Survey, which uses layered satellite, climatic, and biological data to assess distribution and better manage biodiversity. The significant contribution of museum collections to identifying and categorizing species, which is essential for understanding ecological function and for targeting organisms and regions at risk. The book describes our growing understanding of how megacenters of diversity (e.g., rainforest insects, coral reefs) are formed, maintained, and lost; what can be learned from mounting bird extinctions; and how conservation efforts for neotropical primates have fared. It also explores ecosystem restoration, sustainable development, and agricultural impact. Biodiversity II reinforces the idea that the conservation of our biological resources is within reach as long as we pool resources; better coordinate the efforts of existing institutionsâ€"museums, universities, and government agenciesâ€"already dedicated to this goal; and enhance support for research, collections, and training. This volume will be important to environmentalists, biologists, ecologists, educators, students, and concerned individuals.

Knowledge in the field of the biology of the extracellular matrix, and in particular of collagen, has made considerable progress over the last ten years, especially in mammals, birds and ln man with respect to very important applied medical aspects. Basic knowledge in the animal kingdom overall has increased more slowly and haphazardly. We, therefore, considered it useful to organize a meeting specifically devoted to the study of the invertebrate and lower vertebrate collagens. The NATO Scientific Division financed an Advanced Research Workshop aimed at bringing together experts qualified in collagen biology (with morphological, biochemical and genetic specialization) with researchers who are currently studying collagenous tissues of invertebrates and lower vertebrates. The Medical-Biology Committee of the CNR-Rome and the University of Milan also supplied interest and support for the organization of this Meeting. The format of the workshop consisted in: 1) main lectures on the most recent aspects of collagen biology; 2) minireviews on the current knowledge of collagenous tissues in the various invertebrate phyla and in fish; 3) contributed papers on particular aspects of research in specific fields; 4) workshops on the methodology of studying collagen. As we had intended, the Workshop gave a comprehensive overview of acquired knowledge and of the present state of research actlvlty. It permitted wide interdisciplinary discussion, enabling collabora tions to be established and new research themes to be chosen. This volume contains the text of all the contributions presented at the Meeting, including posters.