The annual Evolutionary Biology Meetings in Marseilles serve to gather leading evolutionary biologists and other scientists using evolutionary biology concepts, e.g. for medical research. The aims of these meetings are to promote the exchange of ideas and to encourage interdisciplinary collaborations. This book collects 19 selected contributions presented at the 15th meeting, which took place in September 2011. It starts with a description of the life and work of J.B.S. Haldane, a remarkable evolutionary biologist of the 20th century. The remaining chapters are grouped under the following three themes: · New Concepts in Evolutionary Biology · Macroevolution: Mechanisms and Trends · Genome Evolution Offering an up-to-date overview of recent results in the field of evolutionary biology, this book is an invaluable source of information for scientists, teachers and advanced students.

Comprehensively illustrated and written by leading researchers, this invaluable publication features papers from the annual Evolutionary Biology meetings in Marseilles. It includes a description of the life and work of the celebrated biologist J.B.S. Haldane.

This book examines the toxicological and health implications of environmental epigenetics and provides knowledge through an interdisciplinary approach. Included in this volume are chapters outlining various environmental risk factors such as phthalates and dietary components, life states such as pregnancy and ageing, hormonal and metabolic considerations and specific disease risks such as cancer cardiovascular diseases and other non-communicable diseases. Environmental Epigenetics imparts integrative knowledge of the science of epigenetics and the issues raised in environmental epidemiology. This book is intended to serve both as a reference compendium on environmental epigenetics for scientists in academia, industry and laboratories and as a textbook for graduate level environmental health courses. Environmental Epigenetics imparts integrative knowledge of the science of epigenetics and the issues raised in environmental epidemiology. This book is intended to serve both as a reference compendium on environmental epigenetics for scientists in academia, industry and laboratories and as a textbook for graduate level environmental health courses.

Evolutionary biology has witnessed breathtaking advances in recent years. Some of its most exciting insights have come from the crossover of disciplines as varied as paleontology, molecular biology, ecology, and genetics. This book brings together many of today's pioneers in evolutionary biology to describe the latest advances and explain why a cross-disciplinary and integrated approach to research questions is so essential. Contributors discuss the origins of biological diversity, mechanisms of evolutionary change at the molecular and developmental levels, morphology and behavior, and the ecology of adaptive radiations and speciation. They highlight the mutual dependence of organisms and their environments, and reveal the different strategies today's researchers are using in the field and laboratory to explore this interdependence. Peter and Rosemary Grant--renowned for their influential work on Darwin's finches in the Galápagos--provide concise introductions to each section and identify the key questions future research needs to address. In addition to the editors, the contributors are Myra Awodey, Christopher N. Balakrishnan, Rowan D. H. Barrett, May R. Berenbaum, Paul M. Brakefield, Philip J. Currie, Scott V. Edwards, Douglas J. Emlen, Joshua B. Gross, Hopi E. Hoekstra, Richard Hudson, David Jablonski, David T. Johnston, Mathieu Joron, David Kingsley, Andrew H. Knoll, Mimi A. R. Koehl, June Y. Lee, Jonathan B. Losos, Isabel Santos Magalhaes, Albert B. Phillimore, Trevor Price, Dolph Schluter, Ole Seehausen, Clifford J. Tabin, John N. Thompson, and David B. Wake.

This book contests the general view that natural selection constitutes the explanatory core of evolutionary biology. It invites the reader to consider an alternative view which favors a more complete and multidimensional interpretation. It is common to present the 1930-1960 period as characterized by the rise of the Modern Synthesis, an event structured around two main explanatory commitments: (1) Gradual evolution is explained by small genetic changes (variations) oriented by natural selection, a process leading to adaptation; (2) Evolutionary trends and speciational events are macroevolutionary phenomena that can be accounted for solely in terms of the extension of processes and mechanisms occurring at the previous microevolutionary level. On this view, natural selection holds a central explanatory role in evolutionary theory - one that presumably reaches back to Charles Darwin's Origin of Species - a view also accompanied by the belief that the field of evolutionary biology is organized around a profound divide: theories relying on strong selective factors and those appealing only to weak ones. If one reads the new analyses presented in this volume by biologists, historians and philosophers, this divide seems to be collapsing at a rapid pace, opening an era dedicated to the search for a new paradigm for the development of evolutionary biology. Contrary to popular belief, scholars' position on natural selection is not in itself a significant discriminatory factor between most evolutionists. In fact, the intellectual space is quite limited, if not non-existent, between, on the one hand, "Darwinists", who play down the central role of natural selection in evolutionary explanations, and, on the other hand, "non-Darwinists", who use it in a list of other evolutionary mechanisms. The "mechanism-centered" approach to evolutionary biology is too incomplete to fully make sense of its development. In this book the labels created under the traditional historiography - "Darwinian Revolution", "Eclipse of Darwinism", "Modern Synthesis", "Post-Synthetic Developments" - are thus re-evaluated. This book will not only appeal to researchers working in evolutionary biology, but also to historians and philosophers."

The somatic mechanism of change is little understood. Although astounding advances in molecular biology have opened up new engineering possibilities to "improve" the human species as well as eradicate all kinds of pathological characteristics, such possibilities pose potentially serious dangers. Evolutionary Change explores the biological mechanisms of change in their entirety as they fit into the general dynamics of biological systems and demonstrates the pitfalls of tackling change from too narrow a perspective. Using cancer as an example of certain pathological manifestations of these mechanisms of change, the author posits a challenging new theory of evolution.