Aging of the Autonomic Nervous System is the first book devoted to the aging of the autonomic nervous system. The book presents the most recent findings on topics such as general aspects of the autonomic nervous system, main neurotransmitter systems, age-dependent changes of neuroeffector mechanisms in target organs, and therapeutic perspectives. It also provides a comprehensive analysis of the possible consequences of these findings. Aging of the Autonomic Nervous System will be a useful volume for gerontologists and neuroscientists.

Uric acid disorders are involved in both nephrological and hematological diseases. One of these crystal-associated diseases which has been known since antiquity is gout. More recently, tumor Lysis syndromes have been identified which affect patients with cancer, especially in the phase of cellular destruction after chemotherapy. The detection of these hyperuricemic syndromes, together with the improved understanding of urate handling by the kidney, have spurred new interest in the pathophysiology of hyperuricemic states, their clinical consequences and management. Moreover, the recent development of a recombinant form of urate oxidase transforming uric acid into allantoin (Rasburicase) has caused new interest in the pathophysiology of hyperuricemia and the potential applications of this new drug. The multidisciplinary approach of this book offers new insights into the metabolic syndromes in question by uniting authors from the fields of biochemistry, pharmacology, rheumatology, onco-hematology, and nephrology. The result is a compendium of the present knowledge in the field, which will also be very useful as a reference tool for professionals and students who want to expand their knowledge on this topic.

Science in Byzantium has rarely been systematically explored. A first of its kind, this collection of essays highlights the disciplines, achievements, and contexts of Byzantine science across the eleven centuries of the Byzantine empire. After an introduction on science in Byzantium and the 21st century, and a study of Christianization and the teaching of science in Byzantium, it offers a comprehensive and up-to-date survey of the scientific disciplines cultivated in Byzantium, from the exact to the natural sciences, medicine, polemology, and the occult sciences. The volume showcases the diversity and vivacity of the varied scientific endeavours in the Byzantine world across its long history, and aims to bring the field into broader conversations within Byzantine studies, medieval studies, and history of science. Contributors are Fabio Acerbi, Anne-Laurence Caudano, Gonzalo Andreotti Cruz, Katerina Ierodiakonou, Herve Inglebert, Stavros Lazaris, Divna Manolova, Maria K. Papathanassiou, Inmaculada Pérez Martín, Thomas Salmon, Ioannis Telelis, Anne Tihon, Alain Touwaide, Arnaud Zucker.

Up-to-date discussion of the etiology, diagnosis, treatment, and prevention of this common cause of stroke and cognitive impairment.