This issue serves as a high-level topic review and keeps the readers updated on current and future neurointervention directions.

This issue of Neurosurgery Clinics of North America is devoted to "Minimally Invasive Spine Surgery" and is edited by Zachary A. Smith, MD and Richard G. Fessler, MD, PhD. Articles in this issue include: Complications and complication avoidance of minimally invasive spine surgery; Radiation exposure risk and avoidance; Current techniques in the management of cervical myelopathy and radiculopathy; Thoracic disc/pathology management through minimally invasive routes; Transforaminal Lumbar Interbody fusion: Long term outcomes and complications; Computer-assisted navigation technique for minimally invasive transforaminal lumbar interbody fusion and lateral interbody fusion; Safety and the Anatomy of the retroperitoneal lateral corridor; Minimally invasive extracavitary transpedicular corpectomy for the management of spinal tumors; Minimally invasive anterolateral corpectomy for spinal tumors; Minimally invasive approaches for the management of intramedullary spinal tumors; Percutaneous fixation of thoracolumbar fractures; Advances and feasibility of advanced minimally invasive techniques in deformity correction; Direct lateral approach: Outcomes and Deformity Correction; and Evidence basis and outcomes.

This issue provides a glimpse into how pain can be assessed and managed by several medical disciplines and approaches. It covers classical and conventional techniques as well as innovative techniques.

In this issue, guest editors bring their considerable expertise to this important topic.Provides in-depth reviews on the latest updates in the field, providing actionable insights for clinical practice. Presents the latest information on this timely, focused topic under the leadership of experienced editors in the field. Authors synthesize and distill the latest research and practice guidelines to create these timely topic-based reviews.

This issue of Neurosurgery Clinics of North America is devoted to "Advances in Neuromodulation." Editors Won Kim, MD, Antonio De Salles, MD, and Nader Pouratian, MD have assembled the top experts to review topics such as: peripheral nerve stimulation; spinal cord stimulation for gait reanimation and vascular pathology; deep brain stimulation for Tourettes, OCD, depression, Parkinson’s disease, eating disorders, dystonia, and headache; and techniques for image-guided deep brain stimulation, advanced imaging for targeting, and closed loop neuromodulation.

Central neurocytoma is a tumor of young adults composed of uniform round cells with neuronal differentiation, typically occurring in the lateral ventricles in the region of the foramen of Monro. Neurocytomas is a hot topic in neuro oncology especially with modern developments of radiation and novel chemotherapy agents.

The evidence-based medicine movement is gaining influence in many medical specialties. This issue will cover topics from patient safety in neurosurgery and medical errors, to measuring outcomes for neurosurgical procedures.