Endocrine Pathophysiology offers a comprehensive introduction to diseases of the endocrine system. Rather than providing an overwhelming amount of content on one subject, this book serves as a bridge between basic endocrine physiology and endocrine disorders. Included in the text are case studies covering a variety of endocrine disorders in both inpatient and outpatient settings. With the changes in many medical school curriculums to a clinically-based curriculum, this book provides a cutting-edge approach to endocrine pathophysiology.

This practical guide presents a concise approach to exploring endocrine pathophysiology through the physical exam, emphasizing common clinical signs in endocrinology that can be elicited through inspection, palpation, percussion or auscultation. The established and proposed mechanisms underlying these physical signs are highlighted, allowing students, residents and trainees to better appreciate endocrine pathophysiology at the bedside. The text is organized sensibly to facilitate quick and efficient review by medical trainees. Major diseases in endocrinology are grouped by organ systems - pituitary, thyroid, adrenal, and so on. Specific physical examination findings in each primary endocrine disease are reviewed and grouped under the categories of clinical features and pathophysiology, followed by related clinical and pathophysiology pearls. A brief description of the clinical finding is followed by a summary of the pathophysiologic mechanisms underlying the stated clinical finding. Relevant normal physiology and pathophysiology are reviewed where applicable, to facilitate learning. There are numerous texts on the pathophysiologic basis of diagnostic and laboratory findings in endocrinology. There is, however, no dedicated text to address questions that might be asked by trainees. Endocrine Pathophysiology satisfies this need in the literature.

Traditionally, endocrinology textbooks have been either short notes or multi-author, multi-volume monster, all of which present clinical material last and often only briefly. Endocrinology is different and used real cases to lead readers into the text and then describes the biochemistry, physiology, and anatomy they need to understand the case. The

This book is intended to give readers a “quick look” at metabolic and endocrine physiology. Emphasis is placed on instructional figures, flow diagrams and tables, while text material has been held to a minimum. In general, the endocrine system is first defined and described, and then each endocrine gland is discussed separately. Where appropriate, common endocrine disorders have also been included. This text concisely elucidates the endocrine mechanisms responsible for maintaining homeostatic control of important physiologic variables, and to assist the reader in understanding common pathophysiologic deviations from normal. Over 360 multiple-choice questions gauge the reader’s capacity to effectively understand the subject material. This new edition contains six new chapters covering: hormone disposition, measurement and secretion; bovine, equine and rodent estrus cycles; primate menstrual cycle; male reproductive system; testosterone, estrogen and progesterone; comparative aspects of endocrinology. Learning objectives have been added at the beginning of each chapter and all of the questions are new.

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This volume is designed to enable students to master the science and clinical applications of endocrine pathophysiology and develop the problem-solving skills needed for exams and clinical notations. It methodically explains the pathophysiology of the endocrine system and presents extended patient case studies that demonstrate the link between pathophysiological concepts and clinical reality. This problems-based approach seeks to prepare students to relate basic science to clinical medicine as emphasized in exams.