This new third edition updates a best-selling encyclopedia. It includes about 56% more words than the 1,392-page second edition of 2003. The number of illustrations increased to almost 2,000 and their quality has improved by design and four colors. It includes approximately 1,800 current databases and web servers. This encyclopedia covers the basics and the latest in genomics, proteomics, genetic engineering, small RNAs, transcription factories, chromosome territories, stem cells, genetic networks, epigenetics, prions, hereditary diseases, and patents. Similar integrated information is not available in textbooks or on the Internet.

Available in print and online, this unique reference brings together all four fields of genetics, genomics, proteomics, and bioinformatics to meet your dynamic research requirements. It brings together the latest concepts in these vibrant areas and ensures a truly multidisciplinary approach. Topics include genetic variation and evolution, epigenetics, the human genome, expression profiling, proteome families, structural proteomics, gene finding/gene structure, protein function and annotation, and more. The work incorporates a vast amount of topical information, profiles cutting-edge techniques, and presents the very latest findings from an international team of over five hundred contributors. With articles for both students and more experienced scientists, this is a key reference source for everyone. Contains more than 450 articles covering all aspects of genomics, proteomics, bioinformatics and related technologies Includes a glossary containing over 550 clear and concise definitions "I am pleased to recommend it heartily as a essential reference tool...should remain the definitive work...for many years to come." THE CHEMICAL EDUCATOR "Jorde...and co-editors have done a remarkable job in coordinating this information, distilling it into a package that is both easy to navigate and over-flowing in discovery." ELECTRIC REVIEW

The explosion of the field of genetics over the last decade, with the new technologies that have stimulated research, suggests that a new sort of reference work is needed to keep pace with such a fast-moving and interdisciplinary field. Brenner's Encyclopedia of Genetics, Second Edition, Seven Volume Set, builds on the foundation of the first edition by addressing many of the key subfields of genetics that were just in their infancy when the first edition was published. The currency and accessibility of this foundational content will be unrivalled, making this work useful for scientists and non-scientists alike. Featuring relatively short entries on genetics topics written by experts in that topic, Brenner's Encyclopedia of Genetics, Second Edition, Seven Volume Set provides an effective way to quickly learn about any aspect of genetics, from Abortive Transduction to Zygotes. Adding to its utility, the work provides short entries that briefly define key terms, and a guide to additional reading and relevant websites for further study. Many of the entries include figures to explain difficult concepts. Key terms in related areas such as biochemistry, cell, and molecular biology are also included, and there are entries that describe historical figures in genetics, providing insights into their careers and discoveries. This 7-volume set represents a 25% expansion from the first edition, with over 1600 articles encompassing this burgeoning field Thoroughly up-to-date, with many new topics and subfields covered that were in their infancy or not inexistence at the time of the first edition. Timely coverage of emergent areas such as epigenetics, personalized genomic medicine, pharmacogenetics, and genetic enhancement technologies Interdisciplinary and global in its outlook, as befits the field of genetics Brief articles, written by experts in the field, which not only discuss, define, and explain key elements of the field, but also provide definition of key terms, suggestions for further reading, and biographical sketches of the key people in the history of genetics

It would be possible to challenge the Cell biology through a Cell Philosophy? By re-thinking the cell as a lively Being and subsequently to change the Cell itself into a Being? Into a lively Being? Called CELLULAR BEING? Our ambition, our enterprise, our philosophical and biological ambitions, is encouraged by the huge development of Cell and Molecular Biology in the last decades of the second Millennium and the first two decades of the third Millennium Through the philosophy of cell, through the philosophy of genetic code contained into the DNA, of its physiology and pathology, is enriched thus the self-reflection about the living planetary system into which the Cell itself, in its uni-cellularity or multi-cellularity, has been the oldest living Being, der älteste lebendigen Dasein, Cell is the Being itself, whatever in its uni-cellularity as prokaryote or eukaryote, as unicellular organism, or pluricellular ones, whatever in fungi, in plants or animals, in its physiological conditions or physiopathological ones, being then the basic substratum of all living system in the last of ca. about four billions years… …Then, once again, it is not important the words, into which the books are written, or into which the words are expressed through their morphology or dys-morphology, but the idea or ideas behind them, towards a re-thinking of a concept-o-logical biology, as a revalorization of life itself, Umwertung aller Lebendigewerte, within the uniqueness of our blue planet system… The science of astronomy, the science of cosmology, of geology, of biology, are addressing not only to the readers, whatever they are in the world, but primarily to the bipolarity of readers - thinkers, as the evolutionary development of the word of reader to the concept of thinker, both intertwined into a CONCEPTOLOGICAL FIELD OF CREATORS, through which myself is correlated into the triad reader - thinker - creator… Cellularologist

Why are not enough the first three AERA of our previous AERAS SYSTEMS, namely: AERA OF PHILOSOPHICAL SYSTEMS (AERA - 1) AERA OF SAPIENTOLOGICAL SYSTEMS (AERA - 2) AERA OF VIDEOLOGICAL SYSTEMS (AERA - 3) Being thus necessary a fourth thinkable and re-thinkable Creative System, the one of ARTIFICIAL INTELLIGENCE SYSTEM (AI), which in German Language is entitled as KÜNSTLISCHE INTELLIGENZ (KI), and both AI and KI are under the HYBRID INTELLIGENCE (of Human and Artificial alike or Biology encoded through Technology), re-encoded as HI! Therefore, all three signification, AI-KI-HI, are provable into the sameness extra enlargement of the Classic Human Brain (CHB), which is improved in seconds, in minutes and in hours by Abstract Developer / Entwickler of Human Sapiens (by using accordingly, English – Deutsch and Denglish! This impetus in development of technological systems more and more intelligent, more and more comprehensive, more and more diversified, more and more amplified, comprising here, at least for the time being, information, inspiration, intuition and initiation (Great Four IN-), widespread in areas of science, technology, industry (all three as SCITECH INDUSTRY), of art (ARSSAPIENS INDUSTRY), of Sport (SPORTSAPIENS INDUSTRY), by rethinking thus the Anthropology, the Sapientology, the Cosmology (including here the one of PERSONALISIERTE KOSMOLOGY), of astronomy, of geology and biology, into which all of them means ultimately, another bigger step in development of duality Human-Machine, or a duality of Human-Technology, including the branches of Human-Over-Human-Robotics, or Humanoid-Robotics all as SAPIENS INDUSTRY! The man itself, the human itself, the Sapient-o-Human development, its experiences, its visions, its outcomes, can make symbiosis with oneself, a crossing with its nature of creativity, within the nature-physis of endless philosophy, with tools out of stone, with tools out of bones, the tools out of hood, or of synthetic feature, underlining once again the TOOL - MAKER - MAN, as Homo Faber, or better says, Homo Faber Sapiens, by taking the SAPIENS LIBRARY, wherever He / She goes! But now, within the present data, out of its own virtual reality and creativity, all being improved by the man itself and the machine itself, which machine might in turn overcome the man, by confronting the man itself, by changing and challenging even the human itself, even the Human Sapient oneself in its own destiny and purposes… Could be or could become the Artificial Intelligence (AI / KI / HI) the source and resource, the roots of final ending of the Sapient as Species on the Earth? By taking into account all probabilities and possibilities of the present daily evolution and revolution of the hyper-complexity of Artificial Intelligence (AI / KI / HI), a recombination of the man itself with a machine created by the man itself, could develop a symbiosis of human-machine, which overcomes the Classic Species Sapiens (CSS), who dominated the life on Earth in the last of ca. 50.000 years, by entering within the Species Sapiens Techne (SST), into which the Sapiens still dominate the Universe of Technology, by reaching out in some area even the domination of Technology over Sapiens as TSS! In this way, within Artificial Intelligence (seen and analyzed Three Times Intelligence, i.e., AI-KI-HI, through English - Deutsch - Denglish), the letters themselves, the numbers themselves and the signs themselves, are becoming the WORD itself, through which the WORD itself is improved to the level of CONCEPT itself, and the WORD-CONCEPT DUALITY in their speeding up developing, in their accelerated and amplifying structures, is giving the outcome of the BOOK itself, in its CLASSICAL BOOK (CB), in its digital book as E-BOOK, or in its VIRTUAL BOOK as V-BOOK! Only this multitude of the same BOOK in development, of the same BOOK in diversity, is showing the Genesis the Evolution and the revolution (GENEVO) of the ARTIFICIAL INTELLIGENCE (in its three times of AI - KI - HI), with its versions in German Language as KÜNSTLICHE INTELLIGENZ (KI) and HYBRID INTELLIGENCE (HI), which will be used and reused interchangeably at any reference, or inter-reference or cross-reference in our LANGUAGE OF SAPIENTOSCIENCIA - 1! What really means ENS in our Book of PEKINENSIS SAPIENS (with one – ENS inside the concept of Pekin – ENS - is and one –ENS Sapiens? ENS is a shortage from the Species Sapiens, as essence and existence of it, being thought and rethought as - ENS, i.e., as BEING of the Species Sapiens! Within ENS will be comprise the whole of German Idealist connotation of Being as: A - SEIN = BEING in its maximal generality! B - DASEIN = BEING HERE, on this planetary system! C - MITDASEIN = COBEING HERE, together with all past geological and biological times, influencing and restructuring all basic features of the Planetary Life System! It is possible to rethink the ENS INTO ONESELF RECHATING? Would be ENS a synthesis out of Sapiens! Is ENS a Being (SEIN) out of Sapiens! Is ENS a Being – here (DASEIN) out of Sapiens! Is ENS a CO – BEING – here (MITDASEIN) out of Sapiens! Is ENS a triad of Being empowering the Sapiens oneself! Is ENS a living self-consciousness of the whole of Sapiens! Is ENS a symbiosis between Sapiens and Artificial Intelligence (AI / KI / HI)! Is ENS the dialectic vector of history of the whole Sapiens, in overcoming oneself towards a better Sapient-o-Technology, towards a Sapient-o-post-human-industry in Art, in Philosophy, in Psychology, in Theology? Is ENS in its own powerful skill-ness of Symphony - in - painting, of Symphony - in - sculpturing, of Symphony - in - Architecture, of Symphony - in - poetry, of Symphony - in - theatre, of Symphony - in - music, through which great masterpieces of ARSSAPIENS to be musicalized, and then reunited into an ensemble of unspeakable Symbology of Human – Sapiens – Technology! Is ENS the vector of SAPIENS SYMPHONY, by using and reusing a complex synthesizer of ARSSAPIENS, without precedence in Human – Sapiens – History? All of them are possible, because the writer is now the reader, the explorer is now the surveyor, the survival is now the fighter, by assuming, by affording a strong competition beyond of its own Species, finally, a semi-human-made-device, an Hybrid Intelligence (HI) between biology and technology, both inspired by Bionics resounding in biology and technology alike, as TECHNO – BIO – SAPIENS!! Within these changing and challenging times and adversities, the Culture of Human – Sapiens itself, is coming and becoming a Culture of Wholeness (KULTUR DER GESAMTHEIT, GESAMTHEITKULTUR), including here the Culture of Past times, the Culture of Present Times and the Culture of Future times (KULTUR DER VERGANGENHEIT – KULTUR DE GEGENWART – KULTUR DER ZUKUNFT ((KULTUR DER NÄCHSTENS)). It is to underline that while the Biologic Sapiens has no more powers of regeneration, of coming into biologic mutation, by remaining only the Abstract Powers of Sapiens or Ontology of Creative Sapiens to save, to regenerate and to redemption of our Sapiens Species! Thus, the Biology of Sapiens, the basic Anatomy of Sapiens is remaining a CONSTANT OF SAPIENS, a STATUS QUO SAPIENS, while the ABSTRACT SAPIENS IS A VARIABILITY OF SAPIENS, IS A STATUS DYNAMICS OF SAPIENS! Between the two basic components of Sapiens, its own CONSTANT OF ANATOMY, and its own VARIABILITY OF SAPIENS, as ANATOMONTOLOGY, there are a strong complementary, a DUALITY OF ANATOMY AND ONTOLOGY, which is done through the LOGOS of ANATOMY, as ANATOMOLOGY! This triad of ANATOMY – ANATOMOLOGY – ANATOMONTOLOGY, are the search – research modality of our Sapiens in fighting with its own Technology and Discovery towards overcoming of the Sapiens oneself! In the same time, it is done a Crypto – Anatomy – Analyse and Psychoanalyse, in which is hoped a better knowledge of this Enigma of evolutionary and revolutionary called Sapiens as Species or Genus Homo Sapiens as Genus… To these multitude of questions and answers, to these endlessly uncertainties and un – knows, we try to cope within into our online book, SECRET SAPIENS CODES - 1! EPISTEMOLOGIST OF ARTIFICIAL INTELLIGENCE SYSTEM

…A hard dialectical conversation between a Clinician in Practical Oncology and a Theoretician of the Philosophical Onccologicum… …It is Pragmatism versus Idealism, or the battlefield between the Physician of the Hippocratic Oath and the Metaphysician of the Platonic Eidos... Why this title or belittled through the apparently same term in Oncology, but written into a dissimilarity form, Onccology-Onkkologie? Is it a confrontation between English terminology and the German one? Or a synthesis between the two like in Denglish? Could be this terrible human tumor defeated through a counter tumor? Tumor cell to be annihilated through an Anti-tumor Cell? A cancer cell defeated through an anti-tumor Cell? Could the classical concept to give birth to the anti-concept? Alternatively, classical terminology to give birth to anti-terminology? …to such questions, our endeavor book is trying to give an answer, at least in a theoretical form and expression… Onccologist & Onkkologist